Annotation Detail for DMPK
Basic Information Top
| Gene Symbol: | DMPK ( DM,DM1,DM1PK,DMK,MDPK,MT-PK ) |
|---|---|
| Gene Full Name: | dystrophia myotonica-protein kinase |
| Band: | 19q13.32 |
| Quick Links | Entrez ID:1760; OMIM: 605377; Uniprot ID:DMPK_HUMAN; ENSEMBL ID: ENSG00000104936; HGNC ID: 2933 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 226 | Phosphoserine; by autocatalysis (By | |
| 238 | Phosphoserine; by autocatalysis (By | |
| 244 | Phosphothreonine; by autocatalysis (By | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 226 | Phosphoserine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 |
| 238 | Phosphoserine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 |
| 244 | Phosphothreonine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 11 | Phosphotyrosine(Syk) | HMM predict |
| 11 | Phosphotyrosine(Abl) | HMM predict |
| 24 | Phosphoserine(CDC2) | HMM predict |
| 47 | O-linked | HMM predict |
| 58 | Phosphoserine(CDC2) | HMM predict |
| 60 | O-linked | HMM predict |
| 61 | Phosphothreonine(MAPK) | HMM predict |
| 235 | Phosphothreonine(PKC) | HMM predict |
| 247 | Phosphotyrosine(Jak) | HMM predict |
| 247 | Phosphotyrosine(INSR) | HMM predict |
| 413 | Phosphotyrosine(Jak) | HMM predict |
| 429 | Phosphothreonine(MAPK) | HMM predict |
| 447 | O-linked | HMM predict |
| 453 | Phosphoserine(ATM) | HMM predict |
| 477 | Phosphothreonine(PKC) | HMM predict |
| 546 | O-linked | HMM predict |
| 550 | O-linked | HMM predict |
| 550 | Phosphoserine(CDC2) | HMM predict |
- RefSeq ID: NM_004409
- Location:chr19 50964815-50977575
- strand:-
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| hScc1 | Bcell | GSE12603 | 50964048 | 50965569 | 1521 | 7 |
| p130 | Quiescent | GSE19898 | 50964558 | 50964811 | 253 | 131 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | CD4 | GSE12889 | 50965337 | 50965539 | 202 | 0 |
| CTCF | CD4 | GSE12889 | 50974303 | 50974676 | 373 | 0 |
| CTCF | CD4 | SISSRdata | 50965337 | 50965539 | 202 | 0 |
| CTCF | CD4 | SISSRdata | 50974303 | 50974676 | 373 | 0 |
| CTCF | G2 | GSE9613 | 50965073 | 50965535 | 462 | 0 |
| CTCF | G2 | GSE9613 | 50974058 | 50974759 | 701 | 0 |
| ER | Breast-Cancer | GSE22609 | 50976677 | 50977245 | 568 | 0 |
| ER | MCF7 | GSE19013 | 50976812 | 50977318 | 506 | 0 |
| FOXA1 | MCF7 | GSE15244 | 50975246 | 50975848 | 602 | 0 |
| FoxA1 | MCF7 | MACSdata | 50975450 | 50975676 | 226 | 0 |
| H3ac | HepG2 | E | 50973982 | 50974384 | 402 | 0 |
| Rb | shRbQuiescent | GSE19898 | 50965869 | 50966015 | 146 | 0 |
| TFAP2C | MCF7 | GSE21234 | 50976150 | 50977420 | 1270 | 0 |
| VDR | GM10855-Unstim | GSE22484 | 50963290 | 50966598 | 3308 | 0 |
| VDR | GM10861-stim | GSE22484 | 50963710 | 50968000 | 4290 | 0 |
| hScc1 | Bcell | GSE12603 | 50972723 | 50973192 | 469 | 0 |
| hScc1 | Bcell | GSE12603 | 50974088 | 50974719 | 631 | 0 |
| hScc1 | CdLS | GSE12603 | 50964750 | 50965746 | 996 | 0 |
| p130 | Senescent | GSE19898 | 50965596 | 50966194 | 598 | 0 |
| p130 | shRbSenescent | GSE19898 | 50965564 | 50965992 | 428 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-1 | hsa-mir-1-2 | 18 | 21169019 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 21169019 |
| hsa-miR-1 | hsa-mir-1-2 | 18 | 20487562 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 20487562 |
| hsa-miR-103 | hsa-mir-103-2 | 20 | 20487562 |
| hsa-miR-103 | hsa-mir-103-1 | 5 | 20487562 |
| hsa-miR-107 | hsa-mir-107 | 10 | 20487562 |
| hsa-miR-133a | hsa-mir-133a-1 | 18 | 20487562 |
| hsa-miR-133a | hsa-mir-133a-2 | 20 | 20487562 |
| hsa-miR-133b | hsa-mir-133b | 6 | 21169019 |
| hsa-miR-133b | hsa-mir-133b | 6 | 20487562 |
| hsa-miR-181a | hsa-mir-181a-2 | 9 | 20487562 |
| hsa-miR-181a | hsa-mir-181a-1 | 1 | 20487562 |
| hsa-miR-181a* | hsa-mir-181a-1 | 1 | 20487562 |
| hsa-miR-181a-2* | hsa-mir-181a-2 | 9 | 20487562 |
| hsa-miR-181b | hsa-mir-181b-1 | 1 | 20487562 |
| hsa-miR-181b | hsa-mir-181b-2 | 9 | 20487562 |
| hsa-miR-181c | hsa-mir-181c | 19 | 20487562 |
| hsa-miR-181c* | hsa-mir-181c | 19 | 20487562 |
| hsa-miR-181d | hsa-mir-181d | 19 | 20487562 |
| hsa-miR-206 | hsa-mir-206 | 6 | 21169019 |
| hsa-miR-206 | hsa-mir-206 | 6 | 20487562 |
| hsa-miR-29a | hsa-mir-29a | 7 | 21169019 |
| hsa-miR-29a* | hsa-mir-29a | 7 | 21169019 |
| hsa-miR-29b | hsa-mir-29b-1 | 7 | 21169019 |
| hsa-miR-29b | hsa-mir-29b-2 | 1 | 21169019 |
| hsa-miR-29b-1* | hsa-mir-29b-1 | 7 | 21169019 |
| hsa-miR-29b-2* | hsa-mir-29b-2 | 1 | 21169019 |
| hsa-miR-29c | hsa-mir-29c | 1 | 21169019 |
| hsa-miR-29c* | hsa-mir-29c | 1 | 21169019 |
| hsa-miR-335 | hsa-mir-335 | 7 | 21169019 |
| hsa-miR-335* | hsa-mir-335 | 7 | 21169019 |
| No data |
| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 13361 | EST | chr19 | 50966088 | 50967602 | 168 | mRNA | DMPK | chr19 | 50964815 | 50977576 | Sense/Antisense (SA) pairs | |