AutismKB 2.0

Annotation Detail for DNASE1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DNASE1 ( DKFZp686H0155,DNL1,DRNI,FLJ38093,FLJ44902 )
Gene Full Name: deoxyribonuclease I
Band: 16p13.3
Quick LinksEntrez ID:1773; OMIM: 125505; Uniprot ID:DNAS1_HUMAN; ENSEMBL ID: ENSG00000213918; HGNC ID: 2956
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
40N-linked (GlcNAc...).
128N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
40N-linked (GlcNAc...).Swiss-Prot 53.0
128N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
40N-linkedHMM predict
97Phosphoserine(PKG)HMM predict
98Phosphotyrosine(Syk)HMM predict
112Phosphoserine(IKK)HMM predict
112O-linkedHMM predict
118Phosphotyrosine(Syk)HMM predict
119SulfotyrosineHMM predict
128N-linkedHMM predict
132N-linkedHMM predict
173Phosphotyrosine(Jak)HMM predict
173Phosphotyrosine(Syk)HMM predict
227O-linkedHMM predict
227Phosphothreonine(MAPK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005223
  • Location:chr16 3642940-3648095
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 3636042 3636297 255 6771
FOXA1 MCF7GSE15244 3635764 3637000 1236 6559
Fos K562GSE19551 3632640 3633143 503 10049
Fos K562GSE19551 3636268 3636764 496 6425
FoxA1 MCF7MACSdata 3636178 3636571 393 6566
NRSF pAbJurkat 3635728 3636228 500 6963
RARA MCF7GSE15244 3635811 3637000 1189 6535
TFAP2C MCF7GSE21234 3632603 3633333 730 9973
TFAP2C MCF7GSE21234 3641466 3641964 498 1226
p130 shRbQuiescentGSE19898 3635497 3635938 441 7223
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 3644351 3644556 205 0
CTCF CD4SISSRdata 3644351 3644556 205 0
CTCF G2GSE9613 3644150 3644751 601 0
CTCF G2GSE9613 3646431 3646630 199 0
TFAP2C MCF7GSE21234 3646690 3647626 936 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
9541 mRNA DNASE1 chr16 3642940 3648096 57 mRNA TRAP1 chr16 3648039 3707514Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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