AutismKB 2.0

Annotation Detail for DYNC1H1


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Basic Information Top
Gene Symbol:DYNC1H1 ( DHC1,DHC1a,DKFZp686P2245,DNCH1,DNCL,DNECL,DYHC,Dnchc1,HL-3,KIAA0325,p22 )
Gene Full Name: dynein, cytoplasmic 1, heavy chain 1
Band: 14q32.31
Quick LinksEntrez ID:1778; OMIM: 600112; Uniprot ID:DYHC1_HUMAN; ENSEMBL ID: ENSG00000197102; HGNC ID: 2961
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
371N6-acetyllysine.
394N6-acetyllysine.
754N6-acetyllysine.
1125N6-acetyllysine.
2410Phosphoserine.
2761Phosphoserine.
3379Phosphotyrosine (By similarity).
3480N6-acetyllysine.
4218Phosphothreonine (By similarity).
4221Phosphothreonine (By similarity).
4283N6-acetyllysine.
4368Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001376
  • Location:chr14 101500733-101586887
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 101497125 101497482 357 3430
CTCF CD4SISSRdata 101497125 101497482 357 3430
CTCF HelaGSE12889 101497249 101497513 264 3353
CTCF G2GSE9613 101484861 101485116 255 15745
CTCF G2GSE9613 101496404 101497763 1359 3650
CTCF G2GSE9613 101498141 101498446 305 2440
ER E2-MCF7GSE14664 101495549 101495587 38 5166
ER Fulvestrant-MCF7GSE14664 101495549 101495585 36 5167
ETS1 JurkatGSE17954 101483603 101485077 1474 16394
Fos K562GSE19551 101483802 101484821 1019 16422
H3ac HepG2E 101484179 101484994 815 16147
H3ac HepG2E 101485230 101485758 528 15240
HIF1 HypoHepG2 101483990 101484755 765 16361
Myc K562GSE19551 101493758 101494105 347 6802
P300 T0-glioblastomaGSE21026 101483743 101484861 1118 16432
P300 T30-glioblastomaGSE21026 101483509 101485095 1586 16432
RARA MCF7GSE15244 101483911 101485383 1472 16087
RARG MCF7GSE15244 101483875 101485230 1355 16181
RARG MCF7GSE15244 101496404 101497259 855 3902
Rb QuiescentGSE19898 101483991 101484747 756 16365
Rb SenescentGSE19898 101483916 101484682 766 16435
Rb SenescentGSE19898 101484736 101485245 509 15743
USF1 HepG2E 101483625 101485758 2133 16042
USF1 HepG2E 101486257 101486898 641 14156
USF2 HepG2E 101483875 101485758 1883 15917
USF2 HepG2E 101486257 101486632 375 14289
hScc1 BcellGSE12603 101482732 101482918 186 17909
hScc1 BcellGSE12603 101491787 101492633 846 8524
hScc1 BcellGSE12603 101496440 101497763 1323 3632
hScc1 CdLSGSE12603 101496967 101497763 796 3369
p130 QuiescentGSE19898 101483606 101484232 626 16815
p130 QuiescentGSE19898 101484280 101485103 823 16042
p130 SenescentGSE19898 101483621 101484792 1171 16527
p130 SenescentGSE19898 101484848 101485126 278 15747
p130 shRbQuiescentGSE19898 101483626 101485158 1532 16342
p130 shRbSenescentGSE19898 101483607 101484985 1378 16438
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 101599300 101599482 182 12504
CTCF CD4SISSRdata 101599300 101599482 182 12504
CTCF G2GSE9613 101595201 101595369 168 8398
CTCF G2GSE9613 101599255 101599745 490 12613
Nanog hESGSE18292 101594238 101594469 231 7466
RARG MCF7GSE15244 101591545 101591972 427 4871
TFAP2C MCF7GSE21234 101591173 101592174 1001 4786
hScc1 BcellGSE12603 101599255 101599540 285 12510
hScc1 CdLSGSE12603 101599255 101599796 541 12638
p130 shRbQuiescentGSE19898 101593162 101593692 530 6540
p130 shRbSenescentGSE19898 101593073 101593401 328 6350
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 101543211 101545252 2041 0
CBP JurkatGSE17954 101555603 101557546 1943 0
CBP T30-glioblastomaGSE21026 101516431 101517233 802 0
CTCF G2GSE9613 101500615 101501366 751 0
CTCF G2GSE9613 101579941 101580439 498 0
CTCF G2GSE9613 101582416 101582863 447 0
ER Fulvestrant-MCF7GSE14664 101514923 101514957 34 0
ETS1 JurkatGSE17954 101500096 101501891 1795 0
Fos K562GSE19551 101508357 101509014 657 0
Fos K562GSE19551 101582340 101582828 488 0
FoxA1 MCF7MACSdata 101508507 101508729 222 0
H3K4me3 colorectalcancer 101501882 101502293 411 0
Myc K562GSE19551 101508483 101508970 487 0
Myc K562GSE19551 101582394 101582892 498 0
Oct1 HelaGSE14283 101514056 101514085 29 0
Oct1 HelaGSE14283 101515327 101515362 35 0
Oct1 HelaGSE14283 101550588 101550684 96 0
P300 T30-glioblastomaGSE21026 101508121 101509230 1109 0
P300 T30-glioblastomaGSE21026 101516447 101517195 748 0
PHF8 HeLaGSE20725 101500004 101501791 1787 0
RARA MCF7GSE15244 101582359 101582863 504 0
RARG MCF7GSE15244 101514574 101515072 498 0
RARG MCF7GSE15244 101548299 101548586 287 0
RARG MCF7GSE15244 101563335 101564241 906 0
RARG MCF7GSE15244 101574442 101574724 282 0
STAT1 HeLaGSE12783 101508227 101509190 963 0
STAT1 IFNSISSRdata 101508295 101509060 765 0
TFAP2C MCF7GSE21234 101516723 101517171 448 0
hScc1 BcellGSE12603 101501023 101501404 381 0
hScc1 BcellGSE12603 101528770 101529469 699 0
hScc1 BcellGSE12603 101544893 101545165 272 0
hScc1 CdLSGSE12603 101500615 101501366 751 0
hScc1 CdLSGSE12603 101528689 101529330 641 0
p130 QuiescentGSE19898 101501325 101501548 223 0
p130 QuiescentGSE19898 101586184 101586402 218 0
p130 SenescentGSE19898 101556633 101557001 368 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8398 mRNA DNCH1 chr14 101500736 101586887 522 EST chr14 101585863 101587037Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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