AutismKB 2.0

Annotation Detail for DYNC1I2


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Basic Information Top
Gene Symbol:DYNC1I2 ( DNCI2,FLJ21089,FLJ90842,IC2,MGC104199,MGC111094,MGC9324 )
Gene Full Name: dynein, cytoplasmic 1, intermediate chain 2
Band: 2q31.1
Quick LinksEntrez ID:1781; OMIM: 603331; Uniprot ID:DC1I2_HUMAN; ENSEMBL ID: ENSG00000077380; HGNC ID: 2964
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
87Phosphoserine.
90Phosphoserine (By similarity).
92Phosphoserine.
94Phosphoserine.
95Phosphothreonine.
97Phosphoserine.
101Phosphoserine.
104Phosphoserine.
162Phosphothreonine.
Location(AA) Modifications Resource
87Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
87Phosphoserine(MAPK)HMM predict
89O-linkedHMM predict
90O-linkedHMM predict
92Phosphoserine(IKK)HMM predict
95Phosphothreonine(CDK)HMM predict
101Phosphoserine(ATM)HMM predict
199N-linkedHMM predict
323Phosphothreonine(PKC)HMM predict
362N-linkedHMM predict
365N-linkedHMM predict
368Phosphothreonine(CDK)HMM predict
373Phosphothreonine(CDK)HMM predict
373Phosphothreonine(MAPK)HMM predict
376O-linkedHMM predict
435O-linkedHMM predict
455Phosphoserine(CK1)HMM predict
556N-linkedHMM predict
564O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001378
  • Location:chr2 172252227-172313164
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 172240918 172241059 141 11239
ER E2-MCF7GSE14664 172241447 172241488 41 10760
ER E2-MCF7GSE14664 172241608 172241699 91 10574
ER Fulvestrant-MCF7GSE14664 172240916 172241066 150 11237
Oct1 H2O2-HelaGSE14283 172235012 172235043 31 17200
Oct1 H2O2-HelaGSE14283 172235585 172235614 29 16628
Oct1 HelaGSE14283 172235013 172235042 29 17200
Oct1 HelaGSE14283 172235574 172235612 38 16635
TAF k562GSE8489 172251850 172252578 728 14
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 172327620 172328333 713 14812
FoxA1 MCF7MACSdata 172327671 172327897 226 14620
FoxA1 MCF7MACSdata 172327987 172328217 230 14938
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 172276752 172277395 643 0
CTCF G2GSE9613 172252370 172252743 373 0
ER E2-MCF7GSE14664 172256382 172256414 32 0
ER E2-MCF7GSE14664 172271242 172271283 41 0
ETS1 JurkatGSE17954 172251693 172253180 1487 0
FOXA1 MCF7GSE15244 172252172 172252578 406 0
H3K4me3 colorectalcancer 172252954 172254020 1066 0
H3ac HepG2E 172252100 172254259 2159 0
Oct1 HelaGSE14283 172271035 172271068 33 0
P300 T30-glioblastomaGSE21026 172251678 172253060 1382 0
P300 T30-glioblastomaGSE21026 172276581 172277513 932 0
PHF8 293TGSE20725 172251835 172253157 1322 0
PHF8 Hs68plusFBSGSE20725 172251763 172253564 1801 0
Rb QuiescentGSE19898 172252309 172252634 325 0
Rb QuiescentGSE19898 172252661 172252809 148 0
Rb SenescentGSE19898 172252469 172252985 516 0
Rb shRbSenescenceGSE19898 172252559 172252801 242 0
hScc1 CdLSGSE12603 172268320 172268877 557 0
p130 QuiescentGSE19898 172252189 172253099 910 0
p130 SenescentGSE19898 172251953 172252885 932 0
p130 shRbQuiescentGSE19898 172252220 172252959 739 0
p130 shRbSenescentGSE19898 172251917 172252821 904 0
p63 keratinocytesGSE17611 172272464 172273231 767 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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