AutismKB 2.0

Annotation Detail for DNTT


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Basic Information Top
Gene Symbol:DNTT ( TDT )
Gene Full Name: deoxynucleotidyltransferase, terminal
Band: 10q24.1
Quick LinksEntrez ID:1791; OMIM: 187410; Uniprot ID:TDT_HUMAN; ENSEMBL ID: ENSG00000107447; HGNC ID: 2983
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
10Phosphoserine(CDK)HMM predict
10Phosphoserine(CDC2)HMM predict
26Phosphoserine(ATM)HMM predict
46Phosphothreonine(PKC)HMM predict
68Phosphoserine(CK1)HMM predict
68Phosphoserine(ATM)HMM predict
70Phosphoserine(CK1)HMM predict
70Phosphoserine(ATM)HMM predict
78N-linkedHMM predict
79N-linkedHMM predict
96Phosphoserine(CK2)HMM predict
142PhosphothreonineHMM predict
142Phosphothreonine(MAPK)HMM predict
159Phosphothreonine(PKA)HMM predict
246Phosphotyrosine(EGFR)HMM predict
350Phosphoserine(MAPK)HMM predict
350Phosphoserine(CDC2)HMM predict
353PhosphoserineHMM predict
353Phosphoserine(CK2)HMM predict
354Phosphothreonine(CK2)HMM predict
464Phosphothreonine(PKC)HMM predict
489Phosphoserine(CK1)HMM predict
489Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001017520
  • Location:chr10 98054074-98088308
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 98039184 98039590 406 14688
hScc1 BcellGSE12603 98042881 98043544 663 10862
hScc1 CdLSGSE12603 98042881 98043581 700 10844
hScc1 G2GSE9613 98042881 98043396 515 10936
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 98090158 98090339 181 1940
CTCF CD4SISSRdata 98090158 98090339 181 1940
Oct1 H2O2-HelaGSE14283 98088394 98088428 34 103
Oct1 HelaGSE14283 98088392 98088432 40 104
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 98086827 98087235 408 0
Nanog hESGSE18292 98084804 98084996 192 0
Oct1 H2O2-HelaGSE14283 98056934 98056966 32 0
Oct1 HelaGSE14283 98086739 98086805 66 0
Oct4 hESGSE17917 98059594 98060003 409 0
TFAP2C MCF7GSE21234 98061046 98061505 459 0
hScc1 BcellGSE12603 98084647 98085022 375 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-105 hsa-mir-105-1 X 20039279
hsa-miR-105 hsa-mir-105-2 X 20039279
hsa-miR-10a hsa-mir-10a 17 20039279
hsa-miR-10a* hsa-mir-10a 17 20039279
hsa-miR-15a hsa-mir-15a 13 20039279
hsa-miR-15a* hsa-mir-15a 13 20039279
hsa-miR-182 hsa-mir-182 7 20039279
hsa-miR-182* hsa-mir-182 7 20039279
hsa-miR-188-3p hsa-mir-188 X 20039279
hsa-miR-188-5p hsa-mir-188 X 20039279
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
3513 mRNA DNTT chr10 98054201 98088309 110 EST chr10 98054337 98056511Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018