AutismKB 2.0

Annotation Detail for DPYSL2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DPYSL2 ( CRMP2,DHPRP2,DRP-2,DRP2 )
Gene Full Name: dihydropyrimidinase-like 2
Band: 8p21.2
Quick LinksEntrez ID:1808; OMIM: 602463; Uniprot ID:DPYL2_HUMAN; ENSEMBL ID: ENSG00000092964; HGNC ID: 3014
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
32Phosphotyrosine.
431Phosphotyrosine (By similarity).
462Phosphothreonine (By similarity).
465Phosphoserine (By similarity).
499Phosphotyrosine (By similarity).
509Phosphothreonine.
512Phosphothreonine.
514Phosphothreonine.
517Phosphoserine (By similarity).
518Phosphoserine.
521Phosphothreonine.
522Phosphoserine.
542Phosphoserine (By similarity).
Location(AA) Modifications Resource
462Phosphothreonine (By similarity).Swiss-Prot 53.0
465Phosphoserine (By similarity).Swiss-Prot 53.0
509Phosphothreonine.Swiss-Prot 53.0
509Phosphothreonine (GSK-3beta)Phospho.ELM 6.0
514Phosphothreonine (GSK-3beta)Phospho.ELM 6.0
514Phosphothreonine; in vitro.Swiss-Prot 53.0
518Phosphoserine.Swiss-Prot 53.0
518Phosphoserine (GSK-3beta)Phospho.ELM 6.0
522PhosphoserinePhospho.ELM 6.0
522Phosphoserine.Swiss-Prot 53.0
555Phosphothreonine (ROCK
Location(AA) Modification Resource
32Phosphotyrosine(Syk)HMM predict
36Phosphotyrosine(Syk)HMM predict
131Phosphoserine(IKK)HMM predict
182Phosphotyrosine(Syk)HMM predict
244N-linkedHMM predict
247N-linkedHMM predict
303O-linkedHMM predict
308Phosphoserine(ATM)HMM predict
308Phosphoserine(CDC2)HMM predict
308Phosphoserine(MAPK)HMM predict
308O-linkedHMM predict
308Phosphoserine(CDK)HMM predict
347N-linkedHMM predict
356N-linkedHMM predict
363Phosphoserine(CK1)HMM predict
426N-linkedHMM predict
432N-linkedHMM predict
442Phosphoserine(CDC2)HMM predict
509Phosphothreonine(MAPK)HMM predict
512O-linkedHMM predict
514Phosphothreonine(CDK)HMM predict
514O-linkedHMM predict
514O-linkedHMM predict
514PhosphothreonineHMM predict
514Phosphothreonine(MAPK)HMM predict
517Phosphoserine(CDC2)HMM predict
517O-linkedHMM predict
518O-linkedHMM predict
518O-linkedHMM predict
521Phosphothreonine(PKC)HMM predict
522Phosphoserine(CDC2)HMM predict
522PhosphoserineHMM predict
522Phosphoserine(IKK)HMM predict
555Phosphothreonine(PKC)HMM predict
555Phosphothreonine(PKA)HMM predict
565ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001386
  • Location:chr8 26491337-26571609
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 26484688 26485076 388 6456
CTCF CD4SISSRdata 26484688 26485076 388 6456
CTCF JurkatGSE12889 26484616 26484965 349 6547
CTCF G2GSE9613 26480995 26481267 272 10207
CTCF G2GSE9613 26484746 26485297 551 6316
CTCF G2GSE9613 26490524 26491340 816 406
H3K4me3 colorectalcancer 26490887 26491275 388 257
H3ac HepG2E 26487376 26487876 500 3712
H3ac HepG2E 26488736 26490298 1562 1821
Myc K562GSE19551 26484543 26485219 676 6457
NFkBII GM12878GSE19485 26484237 26486354 2117 6042
NFkBII GM12892GSE19485 26484544 26486123 1579 6004
Oct1 H2O2-HelaGSE14283 26481877 26481905 28 9447
Oct1 HelaGSE14283 26473367 26473397 30 17956
RARG MCF7GSE15244 26487294 26487444 150 3969
Rb GrowingGSE19898 26485627 26485839 212 5605
Rb GrowingGSE19898 26491092 26491414 322 85
Rb QuiescentGSE19898 26491066 26491561 495 24
Rb shRbQuiescentGSE19898 26491083 26491295 212 149
Rb shRbSenescenceGSE19898 26491096 26491302 206 139
TFAP2C MCF7GSE21234 26485571 26486098 527 5503
USF1 HepG2E 26484406 26485145 739 6562
hScc1 BcellGSE12603 26484477 26485557 1080 6321
hScc1 BcellGSE12603 26490440 26491492 1052 372
hScc1 CdLSGSE12603 26484477 26485297 820 6451
hScc1 CdLSGSE12603 26490620 26491375 755 340
hScc1 G2GSE9613 26490524 26491299 775 426
p130 QuiescentGSE19898 26491084 26491402 318 95
p130 SenescentGSE19898 26485628 26486042 414 5503
p130 shRbQuiescentGSE19898 26485092 26486049 957 5767
p130 shRbSenescentGSE19898 26485345 26485908 563 5711
p130 shRbSenescentGSE19898 26491126 26491528 402 11
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 26575353 26575489 136 3812
CTCF CD4GSE12889 26583880 26584286 406 12474
CTCF CD4SISSRdata 26575353 26575489 136 3812
CTCF CD4SISSRdata 26583880 26584286 406 12474
CTCF G2GSE9613 26574959 26575418 459 3579
CTCF G2GSE9613 26583935 26584338 403 12527
FOXA1 DLD1GSE12801 26571395 26572228 833 202
FOXA1 DLD1GSE12801 26572592 26573006 414 1190
Oct4 hESGSE17917 26584050 26584249 199 12540
hScc1 BcellGSE12603 26575092 26575418 326 3646
hScc1 BcellGSE12603 26583935 26584447 512 12582
hScc1 CdLSGSE12603 26574647 26575418 771 3423
hScc1 CdLSGSE12603 26583899 26584447 548 12564
hScc1 G2GSE9613 26574876 26575418 542 3538
hScc1 G2GSE9613 26583972 26584421 449 12587
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 26569037 26569205 168 0
CTCF CD4SISSRdata 26569037 26569205 168 0
CTCF G2GSE9613 26503109 26503468 359 0
CTCF G2GSE9613 26510714 26510873 159 0
CTCF G2GSE9613 26542282 26542547 265 0
CTCF G2GSE9613 26548130 26548420 290 0
CTCF G2GSE9613 26553396 26553572 176 0
CTCF G2GSE9613 26568949 26569451 502 0
ER E2-MCF7GSE14664 26555799 26555847 48 0
ER Fulvestrant-MCF7GSE14664 26555677 26555760 83 0
FOXA1 DLD1GSE12801 26494227 26494766 539 0
FOXA1 DLD1GSE12801 26521867 26522509 642 0
FOXA1 MCF7GSE15244 26491670 26492101 431 0
FoxA1 MCF7MACSdata 26494124 26494352 228 0
H3K4me3 colorectalcancer 26491565 26492130 565 0
H3ac HepG2E 26491492 26492500 1008 0
H3ac HepG2E 26554485 26554888 403 0
NFkBII GM12878GSE19485 26504123 26506034 1911 0
NFkBII GM12878GSE19485 26541379 26542787 1408 0
NFkBII GM12892GSE19485 26541456 26542702 1246 0
Nanog hESGSE18292 26550443 26551004 561 0
Oct1 H2O2-HelaGSE14283 26553084 26553112 28 0
Oct1 H2O2-HelaGSE14283 26561917 26561952 35 0
Oct1 HelaGSE14283 26553084 26553112 28 0
Oct1 HelaGSE14283 26555662 26555768 106 0
Oct1 HelaGSE14283 26561431 26561465 34 0
Oct1 HelaGSE14283 26561913 26561952 39 0
Oct4 hESGSE21916 26491709 26492476 767 0
Rb SenescentGSE19898 26491055 26491653 598 0
TAF HelaGSE8489 26494545 26494766 221 0
TAF HelaGSE8489 26532628 26533020 392 0
TFAP2C MCF7GSE21234 26524953 26525409 456 0
hScc1 BcellGSE12603 26568949 26569637 688 0
hScc1 CdLSGSE12603 26568949 26569303 354 0
hScc1 G2GSE9613 26568949 26569373 424 0
p130 QuiescentGSE19898 26530280 26530424 144 0
p130 SenescentGSE19898 26491114 26491567 453 0
p130 shRbQuiescentGSE19898 26522383 26523872 1489 0
p130 shRbQuiescentGSE19898 26555231 26555471 240 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved