AutismKB 2.0

Annotation Detail for DPYSL3


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Basic Information Top
Gene Symbol:DPYSL3 ( CRMP-4,CRMP4,DRP-3,DRP3,LCRMP,ULIP,ULIP-1 )
Gene Full Name: dihydropyrimidinase-like 3
Band: 5q32
Quick LinksEntrez ID:1809; OMIM: 601168; Uniprot ID:DPYL3_HUMAN; ENSEMBL ID: ENSG00000113657; HGNC ID: 3015
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
499Phosphotyrosine (By similarity).
509Phosphothreonine (By similarity).
514Phosphothreonine (By similarity).
518Phosphoserine (By similarity).
522Phosphoserine.
541Phosphoserine (By similarity).
551Phosphoserine.
Location(AA) Modifications Resource
509Phosphothreonine (By similarity).Swiss-Prot 53.0
522Phosphoserine.Swiss-Prot 53.0
551Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
32Phosphotyrosine(Syk)HMM predict
36Phosphotyrosine(Syk)HMM predict
115Phosphoserine(CK1)HMM predict
303O-linkedHMM predict
308Phosphoserine(MAPK)HMM predict
308Phosphoserine(CDK)HMM predict
308Phosphoserine(CDC2)HMM predict
308Phosphoserine(ATM)HMM predict
308O-linkedHMM predict
316SulfotyrosineHMM predict
347N-linkedHMM predict
363Phosphoserine(CK1)HMM predict
402Phosphoserine(PKG)HMM predict
509Phosphothreonine(CDC2)HMM predict
514PhosphothreonineHMM predict
518O-linkedHMM predict
522Phosphoserine(CDC2)HMM predict
522Phosphoserine(IKK)HMM predict
556IsoleucineHMM predict
563ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001387
  • Location:chr5 146750565-146813452
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 146813611 146813909 298 308
CTCF CD4SISSRdata 146813611 146813909 298 308
CTCF JurkatGSE12889 146813708 146813911 203 357
H3K27me3 colorectalcancer 146814184 146815447 1263 1363
Nanog hESGSE18292 146827657 146828448 791 14600
hScc1 CdLSGSE12603 146812974 146814091 1117 80
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 146763356 146764697 1341 0
CTCF G2GSE9613 146812974 146813560 586 0
H3K27me3 colorectalcancer 146810983 146811756 773 0
H3K27me3 colorectalcancer 146812117 146813113 996 0
Oct1 HelaGSE14283 146767052 146767120 68 0
P300 T30-glioblastomaGSE21026 146763156 146764814 1658 0
Rb GrowingGSE19898 146764495 146764671 176 0
Rb SenescentGSE19898 146764451 146764715 264 0
hScc1 BcellGSE12603 146812974 146813801 827 0
hScc1 CdLSGSE12603 146751557 146751921 364 0
p130 SenescentGSE19898 146763957 146764427 470 0
p130 SenescentGSE19898 146764430 146764787 357 0
p130 shRbSenescentGSE19898 146813229 146813446 217 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018