AutismKB 2.0

Annotation Detail for DSCAM


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Basic Information Top
Gene Symbol:DSCAM ( CHD2-42,CHD2-52 )
Gene Full Name: Down syndrome cell adhesion molecule
Band: 21q22.2
Quick LinksEntrez ID:1826; OMIM: 602523; Uniprot ID:DSCAM_HUMAN; ENSEMBL ID: ENSG00000171587; HGNC ID: 3039
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
28N-linked (GlcNAc...) (Potential).
78N-linked (GlcNAc...) (Potential).
470N-linked (GlcNAc...) (Potential).
487N-linked (GlcNAc...) (Potential).
512N-linked (GlcNAc...) (Potential).
556N-linked (GlcNAc...) (Potential).
658N-linked (GlcNAc...) (Potential).
666N-linked (GlcNAc...) (Potential).
710N-linked (GlcNAc...) (Potential).
748N-linked (GlcNAc...) (Potential).
795N-linked (GlcNAc...) (Potential).
924N-linked (GlcNAc...) (Potential).
1142N-linked (GlcNAc...) (Potential).
1160N-linked (GlcNAc...) (Potential).
1250N-linked (GlcNAc...) (Potential).
1271N-linked (GlcNAc...) (Potential).
1341N-linked (GlcNAc...) (Potential).
1488N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
28N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
78N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
470N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
487N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
512N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
556N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
658N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
666N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
710N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
748N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
795N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
924N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1142N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1160N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1250N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1271N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1341N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1488N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
42O-linkedHMM predict
55Phosphothreonine(PKC)HMM predict
67Phosphotyrosine(INSR)HMM predict
67Phosphotyrosine(SRC)HMM predict
67Phosphotyrosine(Syk)HMM predict
78N-linkedHMM predict
113Phosphoserine(ATM)HMM predict
204Phosphothreonine(PKA)HMM predict
256Phosphotyrosine(SRC)HMM predict
256SulfotyrosineHMM predict
291Phosphotyrosine(INSR)HMM predict
319Phosphoserine(CDC2)HMM predict
326Phosphoserine(PKG)HMM predict
329O-linkedHMM predict
332O-linkedHMM predict
338O-linkedHMM predict
383Phosphotyrosine(EGFR)HMM predict
419Phosphoserine(CDC2)HMM predict
433O-linkedHMM predict
433Phosphothreonine(MAPK)HMM predict
460Phosphothreonine(CK2)HMM predict
470N-linkedHMM predict
512N-linkedHMM predict
556N-linkedHMM predict
573Phosphotyrosine(INSR)HMM predict
584O-linkedHMM predict
586Phosphoserine(CK1)HMM predict
586Phosphoserine(ATM)HMM predict
666N-linkedHMM predict
667Phosphotyrosine(INSR)HMM predict
703Phosphotyrosine(EGFR)HMM predict
710N-linkedHMM predict
763Phosphotyrosine(Jak)HMM predict
764Phosphotyrosine(Jak)HMM predict
795N-linkedHMM predict
796O-linkedHMM predict
797O-linkedHMM predict
848Phosphoserine(CK1)HMM predict
924N-linkedHMM predict
998Phosphoserine(ATM)HMM predict
1043Phosphoserine(CK2)HMM predict
1072Phosphothreonine(PKC)HMM predict
1076Phosphoserine(ATM)HMM predict
1100Phosphothreonine(PKC)HMM predict
1101Phosphoserine(CDC2)HMM predict
1104Phosphoserine(IKK)HMM predict
1106Phosphoserine(CK1)HMM predict
1142N-linkedHMM predict
1158Phosphotyrosine(INSR)HMM predict
1203O-linkedHMM predict
1257Phosphotyrosine(SRC)HMM predict
1271N-linkedHMM predict
1292O-linkedHMM predict
1297Phosphothreonine(CDC2)HMM predict
1324N-linkedHMM predict
1356Phosphotyrosine(INSR)HMM predict
1357Phosphotyrosine(INSR)HMM predict
1386Phosphothreonine(PKC)HMM predict
1388O-linkedHMM predict
1390O-linkedHMM predict
1392Phosphoserine(IKK)HMM predict
1394Phosphoserine(PKA)HMM predict
1421Phosphoserine(CK1)HMM predict
1430Phosphoserine(CDC2)HMM predict
1478Phosphoserine(CK1)HMM predict
1488N-linkedHMM predict
1519O-linkedHMM predict
1528O-linkedHMM predict
1528Phosphoserine(IKK)HMM predict
1633Phosphoserine(IKK)HMM predict
1650Phosphoserine(CK1)HMM predict
1701Phosphothreonine(PKC)HMM predict
1722O-linkedHMM predict
1729N-linkedHMM predict
1735N-linkedHMM predict
1766O-linkedHMM predict
1787Phosphoserine(ATM)HMM predict
1787Phosphoserine(IKK)HMM predict
1789Phosphoserine(ATM)HMM predict
1791Phosphoserine(ATM)HMM predict
1791Phosphoserine(IKK)HMM predict
1800Phosphoserine(IKK)HMM predict
1809Phosphoserine(CK1)HMM predict
1810Phosphothreonine(PKC)HMM predict
1811Phosphotyrosine(Syk)HMM predict
1848O-linkedHMM predict
1855O-linkedHMM predict
1857O-linkedHMM predict
1857Phosphoserine(IKK)HMM predict
1860O-linkedHMM predict
1862O-linkedHMM predict
1862Phosphothreonine(MAPK)HMM predict
1864Phosphoserine(CK1)HMM predict
1874Phosphoserine(CDC2)HMM predict
1874Phosphoserine(CDK)HMM predict
1918Phosphothreonine(PKC)HMM predict
1923Phosphoserine(CK1)HMM predict
1936Phosphothreonine(PKC)HMM predict
1952O-linkedHMM predict
1953Phosphoserine(IKK)HMM predict
1955Phosphoserine(CK1)HMM predict
1988Phosphoserine(ATM)HMM predict
1988PhosphoserineHMM predict
1991Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001389
  • Location:chr21 40306212-41140908
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 40509024 40509286 262 0
CBP T0-glioblastomaGSE21026 40672015 40672410 395 0
CBP T30-glioblastomaGSE21026 40672218 40672457 239 0
CTCF CD4GSE12889 40437680 40437878 198 0
CTCF CD4GSE12889 40680201 40680373 172 0
CTCF CD4SISSRdata 40437680 40437878 198 0
CTCF CD4SISSRdata 40680201 40680373 172 0
CTCF JurkatGSE12889 40806517 40806708 191 0
CTCF G2GSE9613 40476640 40476930 290 0
CTCF G2GSE9613 40680075 40680466 391 0
CTCF G2GSE9613 40806346 40806641 295 0
CTCF G2GSE9613 41135779 41136052 273 0
ER MCF7GSE19013 40607725 40608639 914 0
ER MCF7GSE19013 40612147 40612855 708 0
ER MCF7GSE19013 40614392 40615375 983 0
ER MCF7GSE19013 40617831 40619213 1382 0
ER MCF7GSE19013 40632774 40633366 592 0
ER MCF7GSE19013 40633908 40634987 1079 0
ER MCF7GSE19013 40676369 40677235 866 0
ER MCF7GSE10800 40614690 40615424 734 0
ER MCF7GSE10800 40617993 40619206 1213 0
FOXA1 MCF7GSE15244 40347975 40348564 589 0
FOXA1 MCF7GSE15244 40364450 40365009 559 0
FOXA1 MCF7GSE15244 40423493 40423934 441 0
FOXA1 MCF7GSE15244 40438305 40438780 475 0
FOXA1 MCF7GSE15244 40460006 40461418 1412 0
FOXA1 MCF7GSE15244 40603633 40603797 164 0
FOXA1 MCF7GSE15244 40612162 40612752 590 0
FOXA1 MCF7GSE15244 40614690 40615424 734 0
FOXA1 MCF7GSE15244 40618300 40619177 877 0
FOXA1 MCF7GSE15244 40627708 40628812 1104 0
FOXA1 MCF7GSE15244 40661536 40661979 443 0
FOXA1 MCF7GSE15244 40674895 40675217 322 0
FOXA1 MCF7GSE15244 40676225 40676818 593 0
FOXA1 MCF7GSE15244 40677807 40678080 273 0
FOXA1 MCF7GSE15244 40737882 40738143 261 0
FOXA1 MCF7GSE15244 40739083 40739585 502 0
FOXA1 MCF7GSE15244 40801612 40802257 645 0
FOXA1 MCF7GSE15244 40905418 40905932 514 0
FOXA1 MCF7GSE15244 40936005 40936209 204 0
FOXA1 MCF7GSE15244 40936725 40937362 637 0
FOXA1 MCF7GSE15244 40974491 40974998 507 0
FoxA1 MCF7MACSdata 40347985 40348535 550 0
FoxA1 MCF7MACSdata 40612221 40612522 301 0
FoxA1 MCF7MACSdata 40614942 40615215 273 0
FoxA1 MCF7MACSdata 40676640 40676861 221 0
FoxA1 MCF7MACSdata 40801801 40802123 322 0
NRSF-mono JurkatQuESTdata 40342746 40343051 305 0
NRSF-mono JurkatQuESTdata 40594165 40594473 308 0
NRSF-poly JurkatQuESTdata 40594196 40594441 245 0
Nanog ESGSE20650 40396548 40396945 397 0
Nanog ESGSE20650 40629483 40630140 657 0
Nanog hESGSE18292 40760813 40760969 156 0
P300 T0-glioblastomaGSE21026 40672186 40672408 222 0
RARA MCF7GSE15244 40364271 40365182 911 0
RARA MCF7GSE15244 40367649 40369745 2096 0
RARA MCF7GSE15244 40437608 40437936 328 0
RARA MCF7GSE15244 40460140 40461310 1170 0
RARA MCF7GSE15244 40580417 40581139 722 0
RARA MCF7GSE15244 40607130 40608268 1138 0
RARA MCF7GSE15244 40612201 40613174 973 0
RARA MCF7GSE15244 40614690 40615424 734 0
RARA MCF7GSE15244 40617993 40619441 1448 0
RARA MCF7GSE15244 40624944 40625307 363 0
RARA MCF7GSE15244 40627487 40628395 908 0
RARA MCF7GSE15244 40631440 40633690 2250 0
RARA MCF7GSE15244 40644601 40645646 1045 0
RARA MCF7GSE15244 40661536 40662241 705 0
RARA MCF7GSE15244 40674298 40674546 248 0
RARA MCF7GSE15244 40676117 40676818 701 0
RARA MCF7GSE15244 40677173 40677384 211 0
RARA MCF7GSE15244 40677843 40678080 237 0
RARA MCF7GSE15244 40680977 40681207 230 0
RARA MCF7GSE15244 40711798 40712357 559 0
RARA MCF7GSE15244 40727402 40727874 472 0
RARA MCF7GSE15244 40739083 40740261 1178 0
RARA MCF7GSE15244 40797274 40797916 642 0
RARA MCF7GSE15244 40936689 40937362 673 0
RARA MCF7GSE15244 41013690 41014167 477 0
RARA MCF7GSE15244 41134160 41135849 1689 0
RARG MCF7GSE15244 40364414 40365182 768 0
RARG MCF7GSE15244 40367685 40369778 2093 0
RARG MCF7GSE15244 40438305 40439308 1003 0
RARG MCF7GSE15244 40459662 40461418 1756 0
RARG MCF7GSE15244 40502641 40503019 378 0
RARG MCF7GSE15244 40607841 40608268 427 0
RARG MCF7GSE15244 40612162 40612752 590 0
RARG MCF7GSE15244 40614690 40615954 1264 0
RARG MCF7GSE15244 40618045 40619386 1341 0
RARG MCF7GSE15244 40625052 40625346 294 0
RARG MCF7GSE15244 40627766 40628895 1129 0
RARG MCF7GSE15244 40632457 40633337 880 0
RARG MCF7GSE15244 40661464 40662095 631 0
RARG MCF7GSE15244 40674895 40675217 322 0
RARG MCF7GSE15244 40676189 40676818 629 0
RARG MCF7GSE15244 40677173 40677384 211 0
RARG MCF7GSE15244 40677807 40678080 273 0
RARG MCF7GSE15244 40739083 40739660 577 0
RARG MCF7GSE15244 40977005 40977715 710 0
RARG MCF7GSE15244 41134231 41135225 994 0
RARG MCF7GSE15244 41135491 41135885 394 0
Rb shRbQuiescentGSE19898 40612295 40612474 179 0
Sox2 hESGSE18292 40569437 40569590 153 0
Stat6 IL-4-hr4GSE17850 40540031 40540492 461 0
TAF HelaGSE8489 40660186 40660538 352 0
TFAP2C MCF7GSE21234 40348021 40348705 684 0
TFAP2C MCF7GSE21234 40368549 40368976 427 0
TFAP2C MCF7GSE21234 40618069 40618621 552 0
TFAP2C MCF7GSE21234 40634015 40634525 510 0
TFAP2C MCF7GSE21234 40676172 40677234 1062 0
TFAP2C MCF7GSE21234 40719776 40720164 388 0
hScc1 BcellGSE12603 40437608 40437825 217 0
hScc1 BcellGSE12603 40476414 40476899 485 0
hScc1 BcellGSE12603 40585073 40585399 326 0
hScc1 BcellGSE12603 40680110 40680429 319 0
hScc1 BcellGSE12603 40806421 40806641 220 0
hScc1 BcellGSE12603 40958951 40959181 230 0
hScc1 BcellGSE12603 41135453 41135609 156 0
hScc1 BcellGSE12603 41140645 41140938 293 0
hScc1 CdLSGSE12603 40437608 40438111 503 0
hScc1 G2GSE9613 40437608 40437936 328 0
hScc1 G2GSE9613 40680075 40680466 391 0
hScc1 G2GSE9613 40806346 40806641 295 0
p63 keratinocytesGSE17611 40989767 40990707 940 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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