AutismKB 2.0

Annotation Detail for DUSP4


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Basic Information Top
Gene Symbol:DUSP4 ( HVH2,MKP-2,MKP2,TYP )
Gene Full Name: dual specificity phosphatase 4
Band: 8p12
Quick LinksEntrez ID:1846; OMIM: 602747; Uniprot ID:DUS4_HUMAN; ENSEMBL ID: ENSG00000120875; HGNC ID: 3070
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
117Phosphoserine(PKG)HMM predict
154Phosphotyrosine(EGFR)HMM predict
174Phosphoserine(IKK)HMM predict
174O-linkedHMM predict
227N-linkedHMM predict
345Phosphoserine(CDC2)HMM predict
345Phosphoserine(IKK)HMM predict
359Phosphothreonine(MAPK)HMM predict
379O-linkedHMM predict
383Phosphotyrosine(Jak)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001394
  • Location:chr8 29249538-29264103
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 29279413 29279794 381 15500
FOXA1 MCF7GSE15244 29266025 29266554 529 2186
H3K27me3 colorectalcancer 29267075 29267983 908 3426
H3K27me3 colorectalcancer 29269161 29269669 508 5312
NFkBII GM15510GSE19485 29262366 29265973 3607 66
Oct1 HelaGSE14283 29276380 29276408 28 12291
hScc1 BcellGSE12603 29264348 29264926 578 534
hScc1 BcellGSE12603 29265228 29266267 1039 1644
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 29262112 29262524 412 0
CTCF G2GSE9613 29262947 29264425 1478 0
NFkBII GM12892GSE19485 29260125 29266239 6114 0
hScc1 BcellGSE12603 29262267 29262721 454 0
hScc1 CdLSGSE12603 29261125 29265399 4274 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018