AutismKB 2.0

Annotation Detail for DUSP5


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Basic Information Top
Gene Symbol:DUSP5 ( DUSP,HVH3 )
Gene Full Name: dual specificity phosphatase 5
Band: 10q25.2
Quick LinksEntrez ID:1847; OMIM: 603069; Uniprot ID:DUS5_HUMAN; ENSEMBL ID: ENSG00000138166; HGNC ID: 3071
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
74Nuclear localization signal (Potential).
Location(AA) Modifications Resource
Location(AA) Modification Resource
133Phosphotyrosine(Syk)HMM predict
210N-linkedHMM predict
212O-linkedHMM predict
216Phosphoserine(PKG)HMM predict
298Phosphoserine(IKK)HMM predict
321Phosphothreonine(CDC2)HMM predict
321O-linkedHMM predict
346Phosphoserine(CDK)HMM predict
368O-linkedHMM predict
374O-linkedHMM predict
376Phosphoserine(IKK)HMM predict
376Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004419
  • Location:chr10 112247614-112261289
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 112243099 112244441 1342 3845
H3K27me3 colorectalcancer 112245463 112245950 487 1908
PHF8 Hs68plusFBSGSE20725 112245333 112248793 3460 552
SRF HelaGSE8489 112246391 112246971 580 934
SRF k562GSE8489 112245508 112246971 1463 1375
hScc1 BcellGSE12603 112231563 112231738 175 15964
hScc1 G2GSE9613 112246836 112247869 1033 262
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 112264040 112264538 498 3000
Fos K562GSE19551 112262327 112262948 621 1348
NFkBII GM12878GSE19485 112278042 112280208 2166 17836
hScc1 BcellGSE12603 112263835 112264179 344 2718
hScc1 BcellGSE12603 112279811 112279994 183 18613
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 112250896 112251438 542 0
NFkBII GM10847GSE19485 112246796 112249862 3066 0
STAT1 HeLaGSE12783 112252998 112255261 2263 0
TFAP2C MCF7GSE21234 112249106 112249742 636 0
hScc1 BcellGSE12603 112246873 112249517 2644 0
hScc1 BcellGSE12603 112254222 112254432 210 0
hScc1 BcellGSE12603 112259746 112260065 319 0
hScc1 CdLSGSE12603 112246906 112248364 1458 0
hScc1 CdLSGSE12603 112248643 112249624 981 0
hScc1 CdLSGSE12603 112252757 112253556 799 0
hScc1 G2GSE9613 112248116 112249624 1508 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018