AutismKB 2.0

Annotation Detail for DUSP8


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Basic Information Top
Gene Symbol:DUSP8 ( C11orf81,FLJ42476,FLJ42958,HB5,HVH-5,HVH8 )
Gene Full Name: dual specificity phosphatase 8
Band: 11p15.5
Quick LinksEntrez ID:1850; OMIM: 602038; Uniprot ID:CK081_HUMAN; ENSEMBL ID: ENSG00000184545; HGNC ID: 3074
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
18PhosphoserineHMM predict
76Phosphoserine(PKG)HMM predict
97Phosphoserine(CAMK2)HMM predict
148Phosphoserine(IKK)HMM predict
192N-linkedHMM predict
195N-linkedHMM predict
282Phosphoserine(PKG)HMM predict
282PhosphoserineHMM predict
284Phosphoserine(CDC2)HMM predict
312Phosphothreonine(CDC2)HMM predict
314O-linkedHMM predict
316O-linkedHMM predict
322Phosphoserine(CDC2)HMM predict
322Phosphoserine(ATM)HMM predict
322O-linkedHMM predict
322O-linkedHMM predict
322Phosphoserine(MAPK)HMM predict
337O-linkedHMM predict
363Phosphothreonine(CDK)HMM predict
363Phosphothreonine(MAPK)HMM predict
363O-linkedHMM predict
367O-linkedHMM predict
367O-linkedHMM predict
437Phosphoserine(MAPK)HMM predict
437Phosphoserine(CDK)HMM predict
437Phosphoserine(CDC2)HMM predict
437O-linkedHMM predict
439Phosphoserine(CDC2)HMM predict
439O-linkedHMM predict
439Phosphoserine(IKK)HMM predict
439Phosphoserine(ATM)HMM predict
442Phosphoserine(CDC2)HMM predict
442Phosphoserine(IKK)HMM predict
463PhosphoserineHMM predict
463Phosphoserine(CDC2)HMM predict
463O-linkedHMM predict
463Phosphoserine(CDK)HMM predict
467PhosphoserineHMM predict
467Phosphoserine(CDC2)HMM predict
467Phosphoserine(ATM)HMM predict
467Phosphoserine(CDK)HMM predict
483Phosphothreonine(MAPK)HMM predict
483Phosphothreonine(PKC)HMM predict
514Phosphoserine(CDC2)HMM predict
517Phosphothreonine(MAPK)HMM predict
517Phosphothreonine(CDK)HMM predict
517Phosphothreonine(CDC2)HMM predict
519Phosphoserine(CDC2)HMM predict
519Phosphoserine(CDK)HMM predict
519Phosphoserine(IKK)HMM predict
527Phosphoserine(CDC2)HMM predict
613AlanineHMM predict
614Phosphoserine(CAMK2)HMM predict
614Phosphoserine(IKK)HMM predict
616Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004420
  • Location:chr11 1533958-1549725
  • strand:-
No data
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Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 1542334 1542723 389 0
NRSF pAbJurkat 1545011 1545252 241 0
P300 T0-glioblastomaGSE21026 1537142 1537854 712 0
P300 T30-glioblastomaGSE21026 1536146 1537987 1841 0
Rb shRbQuiescentGSE19898 1539632 1539988 356 0
TFAP2C MCF7GSE21234 1536746 1537914 1168 0
hScc1 BcellGSE12603 1534378 1534644 266 0
hScc1 BcellGSE12603 1535223 1535596 373 0
hScc1 BcellGSE12603 1537122 1537556 434 0
hScc1 BcellGSE12603 1538999 1539892 893 0
hScc1 BcellGSE12603 1545058 1545753 695 0
hScc1 G2GSE9613 1534422 1534644 222 0
hScc1 G2GSE9613 1549262 1549437 175 0
p130 shRbQuiescentGSE19898 1542289 1542783 494 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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