Annotation Detail for E4F1

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Basic Information Top

Gene Symbol:	E4F1 ( E4F,MGC99614 )
Gene Full Name:	E4F transcription factor 1
Band:	16p13.3
Quick Links	Entrez ID:1877; OMIM: 603022; Uniprot ID:E4F1_HUMAN; ENSEMBL ID: ENSG00000167967; HGNC ID: 3121
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:1 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:0 results

Location(AA)	Modification
50	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_004424
Location:chr16 2213567-2225742
strand:+

Upstream the gene:2 results
Downstream the gene:2 results
Inside the gene:19 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Rb	shRbSenescence	GSE19898	2213273	2213540	267	161
p130	Senescent	GSE19898	2213128	2213718	590	145

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
TFAP2C	MCF7	GSE21234	2225402	2226793	1391	355
hScc1	Bcell	GSE12603	2225736	2226037	301	144

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	2213065	2214177	1112	0
CTCF	G2	GSE9613	2219159	2219517	358	0
CTCF	G2	GSE9613	2220748	2221189	441	0
CTCF	G2	GSE9613	2222219	2222493	274	0
CTCF	G2	GSE9613	2223276	2223548	272	0
CTCF	G2	GSE9613	2224076	2224770	694	0
CTCF	G2	GSE9613	2225442	2225809	367	0
ETS1	Jurkat	GSE17954	2212973	2214228	1255	0
FOXA1	MCF7	GSE15244	2216338	2217004	666	0
Oct4	hES	GSE17917	2213459	2213819	360	0
PHF8	HeLa	GSE20725	2213014	2214517	1503	0
PHF8	Hs68minusFBS	GSE20725	2213171	2214022	851	0
PHF8	Hs68plusFBS	GSE20725	2213046	2214303	1257	0
Rb	Growing	GSE19898	2213514	2213704	190	0
Rb	Senescent	GSE19898	2213284	2214262	978	0
TFAP2C	MCF7	GSE21234	2223640	2223938	298	0
VDR	GM10861-Unstim	GSE22484	2212867	2214436	1569	0
p130	Quiescent	GSE19898	2213492	2213722	230	0
p130	shRbSenescent	GSE19898	2213508	2213742	234	0

Validated miRNA targets

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
9479	mRNA	DNASE1L2	chr16	2226468	2228712	230	mRNA	E4F1	chr16	2225690	2226915	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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