AutismKB 2.0

Annotation Detail for ECT2


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Basic Information Top
Gene Symbol:ECT2 ( ARHGEF31,FLJ10461,MGC138291 )
Gene Full Name: epithelial cell transforming sequence 2 oncogene
Band: 3q26.31
Quick LinksEntrez ID:1894; OMIM: 600586; Uniprot ID:ECT2_HUMAN; ENSEMBL ID: ENSG00000114346; HGNC ID: 3155
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
40Phosphoserine.
328Phosphothreonine.
336Phosphoserine.
339Phosphoserine.
342Phosphothreonine.
345Phosphoserine.
811Phosphoserine.
815Phosphothreonine.
858Phosphoserine.
Location(AA) Modifications Resource
328Phosphothreonine.Swiss-Prot 53.0
342Phosphothreonine (CDK1)Phospho.ELM 6.0
411PhosphoserinePhospho.ELM 6.0
413Phosphothreonine (CDK1)Phospho.ELM 6.0
417PhosphoserinePhospho.ELM 6.0
815Phosphothreonine (CDK1)Phospho.ELM 6.0
Location(AA) Modification Resource
5Phosphoserine(IKK)HMM predict
14O-linkedHMM predict
15O-linkedHMM predict
41Phosphotyrosine(INSR)HMM predict
41Phosphotyrosine(EGFR)HMM predict
125N-linkedHMM predict
166Phosphothreonine(PKA)HMM predict
166Phosphothreonine(PKC)HMM predict
189N-linkedHMM predict
201Phosphoserine(PKG)HMM predict
225Phosphotyrosine(Jak)HMM predict
225Phosphotyrosine(Syk)HMM predict
328Phosphothreonine(MAPK)HMM predict
381Phosphoserine(CK1)HMM predict
391Phosphothreonine(MAPK)HMM predict
398SulfotyrosineHMM predict
409O-linkedHMM predict
409Phosphoserine(PKA)HMM predict
411O-linkedHMM predict
412O-linkedHMM predict
413PhosphothreonineHMM predict
413Phosphothreonine(CDK)HMM predict
413Phosphothreonine(MAPK)HMM predict
413O-linkedHMM predict
436Phosphotyrosine(INSR)HMM predict
614Phosphothreonine(PKC)HMM predict
636Phosphoserine(CK1)HMM predict
743Phosphothreonine(CK2)HMM predict
774SulfotyrosineHMM predict
807Phosphothreonine(PKC)HMM predict
807Phosphothreonine(PKA)HMM predict
811Phosphoserine(CAMK2)HMM predict
811Phosphoserine(PKC)HMM predict
815Phosphothreonine(CDC2)HMM predict
835Phosphoserine(CDC2)HMM predict
837PhosphoserineHMM predict
848Phosphoserine(CK1)HMM predict
848Phosphoserine(CK2)HMM predict
851Phosphoserine(CK1)HMM predict
852Phosphoserine(CK1)HMM predict
858Phosphoserine(MAPK)HMM predict
860O-linkedHMM predict
874Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_018098
  • Location:chr3 173954991-174021956
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 173950900 173951228 328 3928
CTCF CD4SISSRdata 173950900 173951228 328 3928
CTCF G2GSE9613 173942997 173943440 443 11773
CTCF G2GSE9613 173950622 173951801 1179 3780
E2F4 G0GSE7516 173950696 173951727 1031 3780
E2F4 SGSE7516 173950935 173951801 866 3624
FOXA1 MCF7GSE15244 173949578 173951801 2223 4302
Fos K562GSE19551 173950748 173951799 1051 3718
FoxA1 MCF7MACSdata 173950746 173951194 448 4022
H3K4me3 colorectalcancer 173951563 173951801 238 3310
H3ac HepG2E 173950809 173952581 1772 3297
LIN54 G0GSE7516 173950773 173951526 753 3842
LIN54 SGSE7516 173950844 173951526 682 3807
LIN9 G0GSE7516 173950622 173951801 1179 3780
LIN9 SGSE7516 173950332 173952225 1893 3713
PHF8 293TGSE20725 173950827 173951902 1075 3627
RARA MCF7GSE15244 173950658 173951305 647 4010
RARG MCF7GSE15244 173950809 173951429 620 3873
hScc1 BcellGSE12603 173950773 173951036 263 4087
hScc1 BcellGSE12603 173951382 173951763 381 3419
hScc1 CdLSGSE12603 173950658 173951590 932 3868
hScc1 G2GSE9613 173950622 173951241 619 4060
hScc1 G2GSE9613 173951563 173951801 238 3310
p130 QuiescentGSE19898 173950592 173951856 1264 3768
p130 SenescentGSE19898 173950772 173951962 1190 3625
p130 shRbQuiescentGSE19898 173950458 173951930 1472 3798
p130 shRbSenescentGSE19898 173950624 173951887 1263 3736
p130 G0GSE7516 173950658 173951801 1143 3762
p130 SGSE7516 173950844 173951801 957 3669
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 174036909 174037139 230 15068
CTCF CD4SISSRdata 174036909 174037139 230 15068
CTCF G2GSE9613 174029152 174029673 521 7456
CTCF G2GSE9613 174031468 174031687 219 9621
CTCF G2GSE9613 174037079 174037272 193 15219
Nanog hESGSE18292 174037056 174037376 320 15260
hScc1 CdLSGSE12603 174037079 174037272 193 15219
hScc1 G2GSE9613 174036853 174037272 419 15106
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 174009752 174010002 250 0
CTCF CD4SISSRdata 174009752 174010002 250 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19003 mRNA ECT2 chr3 173954999 174021965 372 EST chr3 174013072 174013444 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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