AutismKB 2.0

Annotation Detail for EIF2C4


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Basic Information Top
Gene Symbol:EIF2C4 ( AGO4 )
Gene Full Name: eukaryotic translation initiation factor 2C, 4
Band: 1p34.3
Quick LinksEntrez ID:192670; OMIM: 607356; Uniprot ID:AGO4_HUMAN; ENSEMBL ID: ENSG00000134698; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
798Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_017629
  • Location:chr1 36046414-36093774
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 36029924 36029959 35 16473
Oct1 HelaGSE14283 36030641 36030678 37 15755
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 36104862 36104947 85 11130
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 36091200 36091239 39 0
FOXA1 MCF7GSE15244 36047264 36047872 608 0
H3K4me3 colorectalcancer 36047483 36047872 389 0
H3ac HepG2E 36047120 36048555 1435 0
Nanog hESGSE18292 36088255 36088510 255 0
TAF k562GSE8489 36047580 36048414 834 0
hScc1 BcellGSE12603 36046700 36046844 144 0
p63 keratinocytesGSE17611 36073328 36074217 889 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 20144220
hsa-let-7a hsa-let-7a-2 11 20144220
hsa-let-7a hsa-let-7a-3 22 20144220
hsa-let-7a hsa-let-7a-1 9 19898466
hsa-let-7a hsa-let-7a-2 11 19898466
hsa-let-7a hsa-let-7a-3 22 19898466
hsa-let-7a* hsa-let-7a-1 9 20144220
hsa-let-7a* hsa-let-7a-3 22 20144220
hsa-let-7a* hsa-let-7a-1 9 19898466
hsa-let-7a* hsa-let-7a-3 22 19898466
hsa-let-7b hsa-let-7b 22 20144220
hsa-let-7b hsa-let-7b 22 19898466
hsa-let-7b* hsa-let-7b 22 20144220
hsa-let-7b* hsa-let-7b 22 19898466
hsa-let-7c hsa-let-7c 21 20144220
hsa-let-7c hsa-let-7c 21 19898466
hsa-let-7c* hsa-let-7c 21 20144220
hsa-let-7c* hsa-let-7c 21 19898466
hsa-let-7d hsa-let-7d 9 20144220
hsa-let-7d hsa-let-7d 9 19898466
hsa-let-7d* hsa-let-7d 9 20144220
hsa-let-7d* hsa-let-7d 9 19898466
hsa-let-7e hsa-let-7e 19 20144220
hsa-let-7e hsa-let-7e 19 19898466
hsa-let-7e* hsa-let-7e 19 20144220
hsa-let-7e* hsa-let-7e 19 19898466
hsa-let-7f hsa-let-7f-1 9 20144220
hsa-let-7f hsa-let-7f-2 X 20144220
hsa-let-7f hsa-let-7f-1 9 19898466
hsa-let-7f hsa-let-7f-2 X 19898466
hsa-let-7f-1* hsa-let-7f-1 9 20144220
hsa-let-7f-1* hsa-let-7f-1 9 19898466
hsa-let-7f-2* hsa-let-7f-2 X 20144220
hsa-let-7f-2* hsa-let-7f-2 X 19898466
hsa-let-7g hsa-let-7g 3 20144220
hsa-let-7g hsa-let-7g 3 19898466
hsa-let-7g* hsa-let-7g 3 20144220
hsa-let-7g* hsa-let-7g 3 19898466
hsa-let-7i hsa-let-7i 12 20144220
hsa-let-7i hsa-let-7i 12 19898466
hsa-let-7i* hsa-let-7i 12 20144220
hsa-let-7i* hsa-let-7i 12 19898466
hsa-miR-1 hsa-mir-1-2 18 20144220
hsa-miR-1 hsa-mir-1-1 20 20144220
hsa-miR-124 hsa-mir-124-1 8 20144220
hsa-miR-124 hsa-mir-124-2 8 20144220
hsa-miR-124 hsa-mir-124-3 20 20144220
hsa-miR-124 hsa-mir-124-1 8 19898466
hsa-miR-124 hsa-mir-124-2 8 19898466
hsa-miR-124 hsa-mir-124-3 20 19898466
hsa-miR-34a hsa-mir-34a 1 20144220
hsa-miR-34a* hsa-mir-34a 1 20144220
hsa-miR-34b hsa-mir-34b 11 20144220
hsa-miR-34b* hsa-mir-34b 11 20144220
hsa-miR-34c-3p hsa-mir-34c 11 20144220
hsa-miR-34c-5p hsa-mir-34c 11 20144220
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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