AutismKB 2.0

Annotation Detail for EEF1D


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Basic Information Top
Gene Symbol:EEF1D ( EF-1D,EF1D,FLJ20897,FP1047 )
Gene Full Name: eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
Band: 8q24.3
Quick LinksEntrez ID:1936; OMIM: 130592; Uniprot ID:EF1D_HUMAN; ENSEMBL ID: ENSG00000104529; HGNC ID: 3211
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
17N6-acetyllysine.
60Phosphoserine.
107N6-acetyllysine.
117N6-acetyllysine.
119Phosphoserine.
129Phosphothreonine.
133Phosphoserine.
147Phosphothreonine.
162Phosphoserine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
132PhosphoserinePhospho.ELM 6.0
133Phosphoserine.Swiss-Prot 53.0
146PhosphothreoninePhospho.ELM 6.0
147Phosphothreonine.Swiss-Prot 53.0
161PhosphoserinePhospho.ELM 6.0
162Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
91N-linkedHMM predict
119Phosphoserine(CDC2)HMM predict
125O-linkedHMM predict
125Phosphothreonine(PKA)HMM predict
147Phosphothreonine(MAPK)HMM predict
162Phosphoserine(CK2)HMM predict
162PhosphoserineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001960
  • Location:chr8 144733040-144750725
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb QuiescentGSE19898 144750889 144751015 126 227
p130 shRbSenescentGSE19898 144750718 144750988 270 128
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 144749440 144751290 1850 0
FOXA1 MCF7GSE15244 144749663 144750343 680 0
H3K4me3 colorectalcancer 144750037 144750539 502 0
H3ac HepG2E 144749732 144750343 611 0
NRSF pAbJurkat 144733675 144734359 684 0
NRSF pAbJurkat 144741582 144742423 841 0
P300 T30-glioblastomaGSE21026 144748986 144751194 2208 0
RARG MCF7GSE15244 144749663 144750241 578 0
Rb SenescentGSE19898 144749951 144750906 955 0
TFAP2C MCF7GSE21234 144747177 144747907 730 0
TFAP2C MCF7GSE21234 144748823 144750086 1263 0
hScc1 BcellGSE12603 144733161 144734269 1108 0
hScc1 BcellGSE12603 144736103 144736275 172 0
hScc1 BcellGSE12603 144739788 144740327 539 0
hScc1 BcellGSE12603 144745577 144746139 562 0
p130 QuiescentGSE19898 144750115 144750315 200 0
p130 SenescentGSE19898 144750129 144750331 202 0
p130 shRbQuiescentGSE19898 144749946 144750494 548 0
p130 shRbSenescentGSE19898 144749088 144749474 386 0
p130 shRbSenescentGSE19898 144749748 144750026 278 0
p130 shRbSenescentGSE19898 144750137 144750373 236 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
26072 mRNA chr8 144731670 144736615 721 mRNA EEF1D chr8 144733040 144750726Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018