AutismKB 2.0

Annotation Detail for EGF


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Basic Information Top
Gene Symbol:EGF ( HOMG4,URG )
Gene Full Name: epidermal growth factor
Band: 4q25
Quick LinksEntrez ID:1950; OMIM: 131530; Uniprot ID:EGF_HUMAN; ENSEMBL ID: ENSG00000138798; HGNC ID: 3229
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
38N-linked (GlcNAc...) (Potential).
104N-linked (GlcNAc...) (Potential).
117N-linked (GlcNAc...) (Potential).
148N-linked (GlcNAc...) (Potential).
324N-linked (GlcNAc...) (Potential).
404N-linked (GlcNAc...) (Potential).
596N-linked (GlcNAc...) (Potential).
815N-linked (GlcNAc...) (Potential).
926N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
38N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
104N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
117N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
148N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
324N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
404N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
596N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
815N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
926N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
27Phosphoserine(IKK)HMM predict
38N-linkedHMM predict
66Phosphotyrosine(INSR)HMM predict
66Phosphotyrosine(EGFR)HMM predict
66Phosphotyrosine(Abl)HMM predict
104N-linkedHMM predict
117N-linkedHMM predict
148N-linkedHMM predict
149N-linkedHMM predict
324N-linkedHMM predict
404N-linkedHMM predict
406Phosphoserine(PKB)HMM predict
441Phosphoserine(CDC2)HMM predict
475Phosphoserine(IKK)HMM predict
596N-linkedHMM predict
598Phosphoserine(ATM)HMM predict
664Phosphoserine(PKG)HMM predict
680Phosphothreonine(PKA)HMM predict
765S-palmitoylHMM predict
807Phosphoserine(CK1)HMM predict
815N-linkedHMM predict
885O-linkedHMM predict
926N-linkedHMM predict
931N-linkedHMM predict
936Phosphotyrosine(INSR)HMM predict
972Phosphoserine(PKG)HMM predict
1014Phosphotyrosine(Syk)HMM predict
1071Phosphotyrosine(Syk)HMM predict
1156Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001963
  • Location:chr4 111053498-111152867
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 111118554 111118895 341 0
CTCF CD4GSE12889 111139355 111139693 338 0
CTCF CD4GSE12889 111146099 111146361 262 0
CTCF CD4SISSRdata 111118554 111118895 341 0
CTCF CD4SISSRdata 111139355 111139693 338 0
CTCF CD4SISSRdata 111146099 111146361 262 0
CTCF JurkatGSE12889 111146061 111146313 252 0
CTCF G2GSE9613 111118466 111118621 155 0
CTCF G2GSE9613 111119364 111119873 509 0
CTCF G2GSE9613 111139333 111139772 439 0
CTCF G2GSE9613 111140181 111140469 288 0
CTCF G2GSE9613 111146022 111146573 551 0
Fos K562GSE19551 111085737 111086118 381 0
NFkBII GM12878GSE19485 111145860 111146966 1106 0
Nanog hESGSE18292 111093661 111094031 370 0
Nanog hESGSE18292 111146180 111146427 247 0
Oct1 HelaGSE14283 111143904 111143935 31 0
Oct1 HelaGSE14283 111146513 111146541 28 0
P300 T30-glioblastomaGSE21026 111061753 111062368 615 0
Rb GrowingGSE19898 111088096 111088261 165 0
Sox2 hESGSE18292 111146185 111146408 223 0
TFAP2C MCF7GSE21234 111053550 111053961 411 0
hScc1 BcellGSE12603 111145991 111146501 510 0
hScc1 CdLSGSE12603 111145991 111146573 582 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-126 hsa-mir-126 9 18193184
hsa-miR-126* hsa-mir-126 9 18193184
hsa-miR-138 hsa-mir-138-2 16 18193184
hsa-miR-138 hsa-mir-138-1 3 18193184
hsa-miR-141 hsa-mir-141 12 20514023
hsa-miR-141* hsa-mir-141 12 20514023
hsa-miR-145 hsa-mir-145 5 20382746
hsa-miR-145* hsa-mir-145 5 20382746
hsa-miR-15a hsa-mir-15a 13 19342876
hsa-miR-15a* hsa-mir-15a 13 19342876
hsa-miR-200a hsa-mir-200a 1 20514023
hsa-miR-200a* hsa-mir-200a 1 20514023
hsa-miR-200b hsa-mir-200b 1 20514023
hsa-miR-200b* hsa-mir-200b 1 20514023
hsa-miR-200c hsa-mir-200c 12 20514023
hsa-miR-200c* hsa-mir-200c 12 20514023
hsa-miR-206 hsa-mir-206 6 21302623
hsa-miR-212 hsa-mir-212 17 20856931
hsa-miR-429 hsa-mir-429 1 20514023
hsa-miR-7 hsa-mir-7-1 9 16377567
hsa-miR-7 hsa-mir-7-2 15 16377567
hsa-miR-7 hsa-mir-7-3 19 16377567
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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