AutismKB 2.0

Annotation Detail for CELSR3


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Basic Information Top
Gene Symbol:CELSR3 ( CDHF11,EGFL1,FMI1,HFMI1,MEGF2,RESDA1 )
Gene Full Name: cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
Band: 3p21.31
Quick LinksEntrez ID:1951; OMIM: 604264; Uniprot ID:CELR3_HUMAN; ENSEMBL ID: ENSG00000008300; HGNC ID: 3230
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
632N-linked (GlcNAc...) (Potential).
847N-linked (GlcNAc...) (Potential).
1182N-linked (GlcNAc...) (Potential).
1222N-linked (GlcNAc...) (Potential).
1317N-linked (GlcNAc...) (Potential).
1327N-linked (GlcNAc...) (Potential).
1649N-linked (GlcNAc...) (Potential).
1713N-linked (GlcNAc...) (Potential).
1770N-linked (GlcNAc...) (Potential).
1963(3R)-3-hydroxyaspartate (Potential).
2053N-linked (GlcNAc...) (Potential).
2177N-linked (GlcNAc...) (Potential).
2196N-linked (GlcNAc...) (Potential).
2386N-linked (GlcNAc...) (Potential).
2474N-linked (GlcNAc...) (Potential).
2506N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
632N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
847N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1182N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1222N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1317N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1327N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1649N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1713N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1770N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
19633-hydroxyaspartate (Potential).Swiss-Prot 53.0
2053N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2177N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2196N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2386N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2474N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2506N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
16Phosphothreonine(PKA)HMM predict
30Phosphoserine(ATM)HMM predict
49O-linkedHMM predict
94Phosphoserine(PKG)HMM predict
94Phosphoserine(CAMK2)HMM predict
94Phosphoserine(PKB)HMM predict
98Phosphoserine(PKG)HMM predict
154Phosphoserine(CDC2)HMM predict
154Phosphoserine(MAPK)HMM predict
160O-linkedHMM predict
165Phosphoserine(IKK)HMM predict
167N-linkedHMM predict
169O-linkedHMM predict
169Phosphoserine(CDC2)HMM predict
221Phosphothreonine(CK2)HMM predict
222Phosphothreonine(PKC)HMM predict
258Phosphoserine(IKK)HMM predict
265O-linkedHMM predict
279MethylarginineHMM predict
308Phosphothreonine(PKA)HMM predict
309Phosphoserine(PKA)HMM predict
309Phosphoserine(PKA)HMM predict
414Phosphoserine(PKG)HMM predict
441Phosphothreonine(PKC)HMM predict
508PhosphoserineHMM predict
632N-linkedHMM predict
633N-linkedHMM predict
718Phosphoserine(CK1)HMM predict
737O-linkedHMM predict
737O-linkedHMM predict
743O-linkedHMM predict
847N-linkedHMM predict
852N-linkedHMM predict
866Phosphoserine(ATM)HMM predict
946Phosphotyrosine(EGFR)HMM predict
971Phosphoserine(CAMK2)HMM predict
1021Phosphothreonine(PKC)HMM predict
1138Phosphotyrosine(Jak)HMM predict
1145O-linkedHMM predict
1151O-linkedHMM predict
1182N-linkedHMM predict
1222N-linkedHMM predict
1317N-linkedHMM predict
1423S-palmitoylHMM predict
1461S-palmitoylHMM predict
1583O-linkedHMM predict
1585O-linkedHMM predict
1585Phosphothreonine(PKC)HMM predict
1588O-linkedHMM predict
1588Phosphoserine(CDC2)HMM predict
1650Phosphotyrosine(INSR)HMM predict
1659Phosphothreonine(PKC)HMM predict
1664Phosphoserine(PKA)HMM predict
1664Phosphoserine(IKK)HMM predict
1713N-linkedHMM predict
1770N-linkedHMM predict
1776N-linkedHMM predict
1798Phosphothreonine(PKA)HMM predict
1924Phosphothreonine(CDK)HMM predict
1928O-linkedHMM predict
1952O-linkedHMM predict
2053N-linkedHMM predict
2056N-linkedHMM predict
2073Phosphoserine(IKK)HMM predict
2077S-palmitoylHMM predict
2098S-palmitoylHMM predict
2109Phosphoserine(IKK)HMM predict
2112Phosphoserine(CDC2)HMM predict
2118O-linkedHMM predict
2149Phosphothreonine(PKC)HMM predict
2177N-linkedHMM predict
2180Phosphoserine(CDC2)HMM predict
2196N-linkedHMM predict
2230O-linkedHMM predict
2288Phosphoserine(CDC2)HMM predict
2291O-linkedHMM predict
2336Phosphoserine(CDC2)HMM predict
2338MethylarginineHMM predict
2369O-linkedHMM predict
2369Phosphoserine(CDK)HMM predict
2373O-linkedHMM predict
2373Phosphoserine(CDC2)HMM predict
2375O-linkedHMM predict
2383Phosphoserine(IKK)HMM predict
2386N-linkedHMM predict
2388O-linkedHMM predict
2389O-linkedHMM predict
2390O-linkedHMM predict
2390O-linkedHMM predict
2391O-linkedHMM predict
2391Phosphoserine(IKK)HMM predict
2441Phosphoserine(CDC2)HMM predict
2441Phosphoserine(CDK)HMM predict
2474N-linkedHMM predict
2506N-linkedHMM predict
2512S-palmitoylHMM predict
2668Phosphotyrosine(INSR)HMM predict
2668Phosphotyrosine(Syk)HMM predict
2697N-linkedHMM predict
2723Phosphothreonine(PKC)HMM predict
2808N-linkedHMM predict
2809N-linkedHMM predict
2826O-linkedHMM predict
2829O-linkedHMM predict
2829Phosphoserine(IKK)HMM predict
2892Phosphoserine(CK2)HMM predict
2894Phosphoserine(CK1)HMM predict
2896Phosphoserine(CK1)HMM predict
2899Phosphoserine(CK1)HMM predict
2905Phosphoserine(CK1)HMM predict
2907Phosphoserine(CK1)HMM predict
2907Phosphoserine(IKK)HMM predict
2910Phosphoserine(CK2)HMM predict
2911Phosphoserine(CK2)HMM predict
2913Phosphoserine(CK1)HMM predict
2913PhosphoserineHMM predict
2920MethylarginineHMM predict
2994Phosphoserine(IKK)HMM predict
3036Phosphothreonine(PKA)HMM predict
3058O-linkedHMM predict
3058Phosphoserine(IKK)HMM predict
3060Phosphoserine(ATM)HMM predict
3067Phosphoserine(CK1)HMM predict
3101Phosphoserine(ATM)HMM predict
3101Phosphoserine(IKK)HMM predict
3120Phosphothreonine(PKC)HMM predict
3120Phosphothreonine(CDK)HMM predict
3162Phosphothreonine(PKA)HMM predict
3175Phosphoserine(CDC2)HMM predict
3175Phosphoserine(CDK)HMM predict
3195Phosphoserine(CK1)HMM predict
3213Phosphoserine(PKA)HMM predict
3230Phosphoserine(CK1)HMM predict
3230Phosphoserine(IKK)HMM predict
3232Phosphoserine(CK1)HMM predict
3232Phosphoserine(ATM)HMM predict
3232Phosphoserine(IKK)HMM predict
3235O-linkedHMM predict
3254N-linkedHMM predict
3259Phosphoserine(CK1)HMM predict
3265O-linkedHMM predict
3266Phosphothreonine(CDK)HMM predict
3273O-linkedHMM predict
3273O-linkedHMM predict
3275O-linkedHMM predict
3275Phosphothreonine(MAPK)HMM predict
3277O-linkedHMM predict
3277O-linkedHMM predict
3279O-linkedHMM predict
3281O-linkedHMM predict
3281O-linkedHMM predict
3281Phosphoserine(IKK)HMM predict
3286O-linkedHMM predict
3287Phosphothreonine(MAPK)HMM predict
3290O-linkedHMM predict
3295Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001407
  • Location:chr3 48648900-48675351
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 48675212 48677046 1834 778
CTCF CD4GSE12889 48676585 48676884 299 1383
CTCF CD4SISSRdata 48676585 48676884 299 1383
CTCF G2GSE9613 48675250 48676870 1620 709
CTCF G2GSE9613 48677187 48677549 362 2017
FOXA1 MCF7GSE15244 48676122 48676870 748 1145
Myc hESGSE17917 48675805 48676086 281 594
NRSF mAbJurkat 48675450 48676870 1420 809
NRSF mAbJurkat 48677187 48678389 1202 2437
p130 shRbSenescentGSE19898 48675226 48675782 556 153
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 48668537 48668789 252 0
CTCF CD4SISSRdata 48668537 48668789 252 0
CTCF G2GSE9613 48649924 48650183 259 0
CTCF G2GSE9613 48651843 48652401 558 0
CTCF G2GSE9613 48654498 48656636 2138 0
CTCF G2GSE9613 48657199 48657572 373 0
CTCF G2GSE9613 48657823 48658314 491 0
CTCF G2GSE9613 48658684 48659137 453 0
CTCF G2GSE9613 48661120 48661411 291 0
CTCF G2GSE9613 48661751 48662123 372 0
CTCF G2GSE9613 48662837 48664950 2113 0
CTCF G2GSE9613 48665971 48666297 326 0
CTCF G2GSE9613 48668641 48669674 1033 0
CTCF G2GSE9613 48672945 48673285 340 0
ETS1 JurkatGSE17954 48674000 48674610 610 0
H3ac HepG2E 48648942 48650758 1816 0
NRSF JurkatGSE13047 48671104 48677728 6624 0
NRSF mAbJurkat 48669712 48673764 4052 0
NRSF-mono JurkatQuESTdata 48671231 48675120 3889 0
NRSF-poly JurkatQuESTdata 48671622 48676877 5255 0
Rb QuiescentGSE19898 48668586 48668700 114 0
Rb SenescentGSE19898 48668427 48668734 307 0
Rb shRbSenescenceGSE19898 48668468 48668803 335 0
hScc1 BcellGSE12603 48660697 48661012 315 0
hScc1 BcellGSE12603 48668568 48669637 1069 0
hScc1 BcellGSE12603 48674140 48674496 356 0
hScc1 BcellGSE12603 48674785 48675618 833 0
hScc1 G2GSE9613 48654923 48656509 1586 0
p130 shRbSenescentGSE19898 48668560 48668729 169 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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