AutismKB 2.0

Annotation Detail for AHR


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Basic Information Top
Gene Symbol:AHR ( bHLHe76 )
Gene Full Name: aryl hydrocarbon receptor
Band: 7p21.1
Quick LinksEntrez ID:196; OMIM: 600253; Uniprot ID:AHR_HUMAN; ENSEMBL ID: ENSG00000106546; HGNC ID: 348
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
7N-linkedHMM predict
34N-linkedHMM predict
90Phosphoserine(CDC2)HMM predict
179N-linkedHMM predict
222S-palmitoylHMM predict
230N-linkedHMM predict
433N-linkedHMM predict
440Phosphoserine(PKG)HMM predict
440Phosphoserine(IKK)HMM predict
440O-linkedHMM predict
445O-linkedHMM predict
468Phosphotyrosine(Syk)HMM predict
473O-linkedHMM predict
474O-linkedHMM predict
475O-linkedHMM predict
476Phosphoserine(CK1)HMM predict
476Phosphoserine(IKK)HMM predict
478O-linkedHMM predict
487N-linkedHMM predict
491N-linkedHMM predict
505N-linkedHMM predict
592Phosphoserine(CDC2)HMM predict
608N-linkedHMM predict
672Phosphotyrosine(Syk)HMM predict
727O-linkedHMM predict
727Phosphoserine(CDC2)HMM predict
731O-linkedHMM predict
731Phosphothreonine(PKC)HMM predict
808N-linkedHMM predict
819N-linkedHMM predict
820N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001621
  • Location:chr7 17304831-17352296
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me2 HCT116GSE10453 17303560 17304314 754 895
USF1 HepG2E 17303100 17304656 1556 954
USF2 HepG2E 17304026 17304612 586 513
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 17304845 17305473 628 0
H3K4me2 HCT116GSE10453 17305814 17306493 679 0
H3K4me3 colorectalcancer 17305557 17306408 851 0
H3ac HepG2E 17305510 17306989 1479 0
Nanog ESGSE20650 17346825 17347293 468 0
Nanog hESGSE18292 17346769 17347190 421 0
Oct1 HelaGSE14283 17313930 17313960 30 0
Oct4 hESGSE21916 17318801 17319235 434 0
PHF8 HeLaGSE20725 17304343 17305965 1622 0
TAF HelaGSE8489 17305557 17306232 675 0
hScc1 BcellGSE12603 17304612 17305404 792 0
hScc1 BcellGSE12603 17308751 17309241 490 0
hScc1 CdLSGSE12603 17308825 17309267 442 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
309 Unknown MicroArray miR-124 AHR n_a 15685193
407 Unknown FALSE miR-124 Ahr immunoblotting 15806104
688 Unknown FALSE miR-375 Ahr immunoblotting 15806104
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000106546 G1-to-S transition n_a n_a "epithelium, squamous cell, lymphoblast, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
ENSG00000106546 G1-to-S transition n_a n_a n_a n_a
ENSG00000106546 n_a n_a n_a n_a n_a
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23683 mRNA AHR chr7 17111485 17158632 270 EST chr7 17099280 17112221Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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