AutismKB 2.0

Annotation Detail for EME2


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Basic Information Top
Gene Symbol:EME2 ( FLJ00151,SLX2B,gs125 )
Gene Full Name: essential meiotic endonuclease 1 homolog 2 (S. pombe)
Band: 16p13.3
Quick LinksEntrez ID:197342; OMIM: 610886; Uniprot ID:EME2_HUMAN; ENSEMBL ID: ENSG00000197774; HGNC ID: 27289
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001010865
  • Location:chr16 1763229-1766238
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 293TGSE20725 1762572 1763818 1246 35
Rb SenescentGSE19898 1763015 1763401 386 22
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF pAbJurkat 1766116 1766598 482 119
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 1763353 1763634 281 0
CTCF CD4SISSRdata 1763353 1763634 281 0
CTCF G2GSE9613 1762829 1764059 1230 0
NFkBII GM15510GSE19485 1762637 1763972 1335 0
PHF8 HeLaGSE20725 1762241 1764272 2031 0
TAF HelaGSE8489 1763754 1764254 500 0
VDR GM10861-stimGSE22484 1762508 1764068 1560 0
hScc1 BcellGSE12603 1763249 1764097 848 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018