Annotation Detail for EIF4E
Basic Information Top
Gene Symbol: | EIF4E ( CBP,EIF4E1,EIF4EL1,EIF4F,MGC111573 ) |
---|---|
Gene Full Name: | eukaryotic translation initiation factor 4E |
Band: | 4q23 |
Quick Links | Entrez ID:1977; OMIM: 133440; Uniprot ID:IF4E_HUMAN; ENSEMBL ID: ENSG00000151247; HGNC ID: 3287 |
Relate to Another Database: | SFARIGene; denovo-db |
Location(AA) | Modification | |
---|---|---|
2 | N-acetylalanine. | |
209 | Phosphoserine; by PKC. |
Location(AA) | Modifications | Resource |
---|---|---|
53 | Phosphoserine | Phospho.ELM 6.0 |
209 | Phosphoserine (by PKC). | Swiss-Prot 53.0 |
209 | Phosphoserine (Mnk1;Mnk2) | Phospho.ELM 6.0 |
Location(AA) | Modification | Resource |
---|---|---|
9 | O-linked | HMM predict |
9 | O-linked | HMM predict |
9 | O-linked | HMM predict |
34 | Phosphotyrosine(EGFR) | HMM predict |
53 | Phosphoserine(CK1) | HMM predict |
141 | Phosphoserine(CK2) | HMM predict |
145 | Sulfotyrosine | HMM predict |
207 | Phosphoserine(IKK) | HMM predict |
- RefSeq ID: NM_001968
- Location:chr4 100020235-100070138
- strand:-
Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
---|---|---|---|---|---|---|
CTCF | G2 | GSE9613 | 100080102 | 100080386 | 284 | 10106 |
Oct1 | H2O2-Hela | GSE14283 | 100080444 | 100080482 | 38 | 10325 |
Oct1 | Hela | GSE14283 | 100080442 | 100080487 | 45 | 10326 |
Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
---|---|---|---|---|---|---|
Myc | K562 | GSE19551 | 100001377 | 100001752 | 375 | 18671 |
Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
---|---|---|---|---|---|---|
CTCF | G2 | GSE9613 | 100068467 | 100069249 | 782 | 0 |
ER | E2-MCF7 | GSE14664 | 100039012 | 100039053 | 41 | 0 |
ER | E2-MCF7 | GSE14664 | 100039218 | 100039254 | 36 | 0 |
ETS1 | Jurkat | GSE17954 | 100067770 | 100070057 | 2287 | 0 |
Fos | K562 | GSE19551 | 100069030 | 100069820 | 790 | 0 |
H3K4me3 | colorectal | cancer | 100067870 | 100068699 | 829 | 0 |
H3K4me3 | colorectal | cancer | 100069865 | 100070109 | 244 | 0 |
H3ac | HepG2 | E | 100067870 | 100069090 | 1220 | 0 |
H3ac | HepG2 | E | 100069362 | 100070665 | 1303 | 0 |
Myc | K562 | GSE19551 | 100032102 | 100032374 | 272 | 0 |
Oct1 | H2O2-Hela | GSE14283 | 100050143 | 100050178 | 35 | 0 |
Oct1 | H2O2-Hela | GSE14283 | 100065315 | 100065342 | 27 | 0 |
Oct1 | Hela | GSE14283 | 100050142 | 100050182 | 40 | 0 |
Oct1 | Hela | GSE14283 | 100065314 | 100065343 | 29 | 0 |
PHF8 | 293T | GSE20725 | 100068174 | 100070136 | 1962 | 0 |
USF1 | HepG2 | E | 100067870 | 100070908 | 3038 | 0 |
USF2 | HepG2 | E | 100067870 | 100070534 | 2664 | 0 |
hScc1 | Bcell | GSE12603 | 100068532 | 100069403 | 871 | 0 |
hScc1 | Bcell | GSE12603 | 100069968 | 100070109 | 141 | 0 |
p63 | keratinocytes | GSE17611 | 100030696 | 100031542 | 846 | 0 |
Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
---|---|---|---|
hsa-let-7a | hsa-let-7a-1 | 9 | 17656684 |
hsa-let-7a | hsa-let-7a-2 | 11 | 17656684 |
hsa-let-7a | hsa-let-7a-3 | 22 | 17656684 |
hsa-let-7a | hsa-let-7a-1 | 9 | 17524464 |
hsa-let-7a | hsa-let-7a-2 | 11 | 17524464 |
hsa-let-7a | hsa-let-7a-3 | 22 | 17524464 |
hsa-let-7a* | hsa-let-7a-1 | 9 | 17656684 |
hsa-let-7a* | hsa-let-7a-3 | 22 | 17656684 |
hsa-let-7a* | hsa-let-7a-1 | 9 | 17524464 |
hsa-let-7a* | hsa-let-7a-3 | 22 | 17524464 |
hsa-let-7b | hsa-let-7b | 22 | 17656684 |
hsa-let-7b | hsa-let-7b | 22 | 17524464 |
hsa-let-7b | hsa-let-7b | 22 | 18668040 |
hsa-let-7b* | hsa-let-7b | 22 | 17656684 |
hsa-let-7b* | hsa-let-7b | 22 | 17524464 |
hsa-let-7b* | hsa-let-7b | 22 | 18668040 |
hsa-let-7c | hsa-let-7c | 21 | 17656684 |
hsa-let-7c | hsa-let-7c | 21 | 17524464 |
hsa-let-7c* | hsa-let-7c | 21 | 17656684 |
hsa-let-7c* | hsa-let-7c | 21 | 17524464 |
hsa-let-7d | hsa-let-7d | 9 | 17656684 |
hsa-let-7d | hsa-let-7d | 9 | 17524464 |
hsa-let-7d* | hsa-let-7d | 9 | 17656684 |
hsa-let-7d* | hsa-let-7d | 9 | 17524464 |
hsa-let-7e | hsa-let-7e | 19 | 17656684 |
hsa-let-7e | hsa-let-7e | 19 | 17524464 |
hsa-let-7e* | hsa-let-7e | 19 | 17656684 |
hsa-let-7e* | hsa-let-7e | 19 | 17524464 |
hsa-let-7f | hsa-let-7f-1 | 9 | 17656684 |
hsa-let-7f | hsa-let-7f-2 | X | 17656684 |
hsa-let-7f | hsa-let-7f-1 | 9 | 17524464 |
hsa-let-7f | hsa-let-7f-2 | X | 17524464 |
hsa-let-7f-1* | hsa-let-7f-1 | 9 | 17656684 |
hsa-let-7f-1* | hsa-let-7f-1 | 9 | 17524464 |
hsa-let-7f-2* | hsa-let-7f-2 | X | 17656684 |
hsa-let-7f-2* | hsa-let-7f-2 | X | 17524464 |
hsa-let-7g | hsa-let-7g | 3 | 17656684 |
hsa-let-7g | hsa-let-7g | 3 | 17524464 |
hsa-let-7g* | hsa-let-7g | 3 | 17656684 |
hsa-let-7g* | hsa-let-7g | 3 | 17524464 |
hsa-let-7i | hsa-let-7i | 12 | 17656684 |
hsa-let-7i | hsa-let-7i | 12 | 17524464 |
hsa-let-7i* | hsa-let-7i | 12 | 17656684 |
hsa-let-7i* | hsa-let-7i | 12 | 17524464 |
hsa-miR-1 | hsa-mir-1-2 | 18 | 18668040 |
hsa-miR-1 | hsa-mir-1-1 | 20 | 18668040 |
hsa-miR-141 | hsa-mir-141 | 12 | 21238942 |
hsa-miR-141* | hsa-mir-141 | 12 | 21238942 |
hsa-miR-145 | hsa-mir-145 | 5 | 21092188 |
hsa-miR-145* | hsa-mir-145 | 5 | 21092188 |
hsa-miR-155 | hsa-mir-155 | 21 | 18668040 |
hsa-miR-155* | hsa-mir-155 | 21 | 18668040 |
hsa-miR-16 | hsa-mir-16-1 | 13 | 18668040 |
hsa-miR-16 | hsa-mir-16-2 | 3 | 18668040 |
hsa-miR-30a | hsa-mir-30a | 6 | 18668040 |
hsa-miR-30a* | hsa-mir-30a | 6 | 18668040 |
hsa-miR-30b | hsa-mir-30b | 8 | 18668040 |
hsa-miR-30b* | hsa-mir-30b | 8 | 18668040 |
hsa-miR-30c | hsa-mir-30c-2 | 6 | 18668040 |
hsa-miR-30c | hsa-mir-30c-1 | 1 | 18668040 |
hsa-miR-30c-1* | hsa-mir-30c-1 | 1 | 18668040 |
hsa-miR-30c-2* | hsa-mir-30c-2 | 6 | 18668040 |
hsa-miR-30d | hsa-mir-30d | 8 | 18668040 |
hsa-miR-30d* | hsa-mir-30d | 8 | 18668040 |
hsa-miR-30e | hsa-mir-30e | 1 | 18668040 |
hsa-miR-30e* | hsa-mir-30e | 1 | 18668040 |
ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
---|---|---|---|---|---|---|
1037 | Unknown | pSILAC | miR-16 | EIF4E | down 50-25% | 18668040 |
Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
ENSG00000151247 | n_a | n_a | n_a | "lymphocyte, muscle cell" | "malignant tumour, carcinoma, leukaemia, sarcoma" |