AutismKB 2.0

Annotation Detail for EIF4G2


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Basic Information Top
Gene Symbol:EIF4G2 ( AAG1,DAP5,FLJ41344,NAT1,P97 )
Gene Full Name: eukaryotic translation initiation factor 4 gamma, 2
Band: 11p15.4
Quick LinksEntrez ID:1982; OMIM: 602325; Uniprot ID:IF4G2_HUMAN; ENSEMBL ID: ENSG00000110321; HGNC ID: 3297
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
395Phosphoserine.
508Phosphothreonine.
514Phosphothreonine.
902Phosphoserine (By similarity).
Location(AA) Modifications Resource
1N-acetylmethionine.Swiss-Prot 53.0
508Phosphothreonine.Swiss-Prot 53.0
508PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
14O-linkedHMM predict
22O-linkedHMM predict
23MethylarginineHMM predict
56Phosphothreonine(PKC)HMM predict
128Phosphotyrosine(INSR)HMM predict
128Phosphotyrosine(SRC)HMM predict
177N-linkedHMM predict
181N-linkedHMM predict
436Phosphoserine(ATM)HMM predict
448Phosphoserine(ATM)HMM predict
462Phosphoserine(CK1)HMM predict
500O-linkedHMM predict
500Phosphoserine(CDK)HMM predict
508Phosphothreonine(CDK)HMM predict
533Phosphothreonine(PKC)HMM predict
534O-linkedHMM predict
534Phosphoserine(PKG)HMM predict
593Phosphoserine(ATM)HMM predict
593PhosphoserineHMM predict
602Phosphoserine(CK1)HMM predict
746Phosphoserine(ATM)HMM predict
788Phosphoserine(CK2)HMM predict
793Phosphoserine(CK1)HMM predict
798Phosphoserine(CK1)HMM predict
902Phosphoserine(CK1)HMM predict
902Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001418
  • Location:chr11 10775169-10787157
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAF k562GSE8489 10787479 10788469 990 817
p130 QuiescentGSE19898 10787254 10787903 649 421
p130 shRbQuiescentGSE19898 10787223 10787923 700 416
p130 shRbSenescentGSE19898 10786560 10787886 1326 66
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 10770557 10770937 380 4423
CTCF CD4SISSRdata 10770557 10770937 380 4423
TAFII hESGSE17917 10770634 10770878 244 4414
hScc1 BcellGSE12603 10770179 10771164 985 4498
hScc1 CdLSGSE12603 10770396 10771198 802 4373
hScc1 G2GSE9613 10770288 10771198 910 4427
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 10786530 10787527 997 0
H3K4me3 colorectalcancer 10784732 10786017 1285 0
H3ac HepG2E 10784616 10786373 1757 0
PHF8 293TGSE20725 10786118 10788062 1944 0
PHF8 Hs68plusFBSGSE20725 10785904 10787994 2090 0
Pol2 GM12878GSE19551 10785556 10787769 2213 0
hScc1 BcellGSE12603 10786373 10787323 950 0
p130 SenescentGSE19898 10786324 10787113 789 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018