AutismKB 2.0

Annotation Detail for EIF5


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Basic Information Top
Gene Symbol:EIF5 ( EIF-5A )
Gene Full Name: eukaryotic translation initiation factor 5
Band: 14q32.32
Quick LinksEntrez ID:1983; OMIM: 601710; Uniprot ID:IF5_HUMAN; ENSEMBL ID: ENSG00000100664; HGNC ID: 3299
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
10Phosphoserine.
149Phosphoserine.
229Phosphoserine.
389Phosphoserine.
390Phosphoserine.
405Phosphotyrosine.
410Phosphoserine.
419Phosphoserine.
Location(AA) Modifications Resource
389Phosphoserine.Swiss-Prot 53.0
389Phosphoserine (CK2 alpha)Phospho.ELM 6.0
390Phosphoserine.Swiss-Prot 53.0
390Phosphoserine (CK2 alpha)Phospho.ELM 6.0
Location(AA) Modification Resource
74Phosphotyrosine(INSR)HMM predict
77N-linkedHMM predict
83N-linkedHMM predict
149Phosphoserine(CK1)HMM predict
151Phosphoserine(CK1)HMM predict
170N-linkedHMM predict
172Phosphoserine(IKK)HMM predict
174Phosphoserine(CK2)HMM predict
174O-linkedHMM predict
176O-linkedHMM predict
176Phosphoserine(IKK)HMM predict
178Phosphothreonine(CDK)HMM predict
178Phosphothreonine(CDC2)HMM predict
178O-linkedHMM predict
389Phosphoserine(CK1)HMM predict
390Phosphoserine(ATM)HMM predict
390Phosphoserine(CK1)HMM predict
410PhosphoserineHMM predict
410Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001969
  • Location:chr14 102870245-102881111
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 102854498 102854637 139 15678
ETS1 JurkatGSE17954 102869439 102870789 1350 132
Fos K562GSE19551 102869800 102870604 804 44
Gata1 K562GSE18868 102850523 102851166 643 19401
Gata2 K562GSE18868 102850530 102851113 583 19424
NFkBII GM15510GSE19485 102869307 102870961 1654 112
PHF8 Hs68minusFBSGSE20725 102869399 102870767 1368 163
PHF8 Hs68plusFBSGSE20725 102869139 102871095 1956 129
TAF HelaGSE8489 102868159 102868964 805 1684
TAF k562GSE8489 102868118 102868964 846 1705
VDR GM10861-stimGSE22484 102854635 102856364 1729 14746
hScc1 BcellGSE12603 102850714 102850934 220 19422
hScc1 BcellGSE12603 102852814 102852956 142 17361
p130 shRbQuiescentGSE19898 102869445 102870378 933 334
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 102870153 102870908 755 0
PHF8 HeLaGSE20725 102869251 102871281 2030 0
hScc1 CdLSGSE12603 102869303 102871353 2050 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-15b hsa-mir-15b 3 16609010
hsa-miR-15b* hsa-mir-15b 3 16609010
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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