AutismKB 2.0

Annotation Detail for SERPINB1


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Basic Information Top
Gene Symbol:SERPINB1 ( EI,ELANH2,LEI,M/NEI,MNEI,PI2 )
Gene Full Name: serpin peptidase inhibitor, clade B (ovalbumin), member 1
Band: 6p25.2
Quick LinksEntrez ID:1992; OMIM: 130135; Uniprot ID:ILEU_HUMAN; ENSEMBL ID: ENSG00000021355; HGNC ID: 3311
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine.
137N6-acetyllysine.
177N6-acetyllysine.
282Phosphotyrosine.
286Phosphoserine.
Location(AA) Modifications Resource
1N-acetylmethionine.Swiss-Prot 53.0
Location(AA) Modification Resource
31Phosphoserine(CDC2)HMM predict
34O-linkedHMM predict
72Phosphoserine(IKK)HMM predict
140Phosphothreonine(PKC)HMM predict
155N-linkedHMM predict
251Phosphothreonine(PKC)HMM predict
270N-linkedHMM predict
298N-linkedHMM predict
351N-linkedHMM predict
365N-linkedHMM predict
375ArginineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_030666
  • Location:chr6 2778734-2787079
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 2798823 2800194 1371 12429
CTCF G2GSE9613 2791645 2792109 464 4798
CTCF G2GSE9613 2798342 2798513 171 11348
CTCF G2GSE9613 2799233 2800031 798 12553
Fos K562GSE19551 2798892 2799331 439 12032
H3ac HepG2E 2799330 2800906 1576 13039
NFkBII GM12878GSE19485 2802203 2805148 2945 16596
NFkBII GM12892GSE19485 2802181 2803743 1562 15883
NFkBII GM15510GSE19485 2802331 2804860 2529 16516
NFkBII GM18505GSE19485 2801871 2804744 2873 16228
Nanog hESGSE18292 2791606 2791942 336 4695
P300 T30-glioblastomaGSE21026 2798907 2800196 1289 12472
RARA MCF7GSE15244 2787183 2787481 298 253
RARA MCF7GSE15244 2797250 2798342 1092 10717
hScc1 BcellGSE12603 2791645 2792291 646 4889
hScc1 BcellGSE12603 2800447 2800801 354 13545
hScc1 CdLSGSE12603 2791645 2792529 884 5008
hScc1 G2GSE9613 2791645 2792474 829 4980
p130 QuiescentGSE19898 2803306 2803495 189 16321
p130 SenescentGSE19898 2787030 2787155 125 13
p130 SenescentGSE19898 2803180 2803497 317 16259
p130 shRbQuiescentGSE19898 2798929 2799425 496 12098
p130 shRbSenescentGSE19898 2802767 2803617 850 16113
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 2785047 2785460 413 0
H3ac HepG2E 2784666 2786568 1902 0
NRSF JurkatGSE13047 2782802 2783083 281 0
NRSF JurkatSISSRdata 2782875 2783065 190 0
PolII HeLaGSE12783 2780100 2788209 8109 0
Rb GrowingGSE19898 2786654 2786875 221 0
p130 QuiescentGSE19898 2786392 2786992 600 0
p130 SenescentGSE19898 2786357 2786962 605 0
p130 shRbSenescentGSE19898 2786441 2786653 212 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018