AutismKB 2.0

Annotation Detail for ELK1


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Basic Information Top
Gene Symbol:ELK1 ( - )
Gene Full Name: ELK1, member of ETS oncogene family
Band: Xp11.23
Quick LinksEntrez ID:2002; OMIM: 311040; Uniprot ID:ELK1_HUMAN; ENSEMBL ID: ENSG00000126767; HGNC ID: 3321
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
324Phosphoserine; by MAPK1.
336Phosphothreonine; by MAPK1.
383Phosphoserine; by MAPK1.
389Phosphoserine; by MAPK1.
422Phosphoserine; by MAPK1.
Location(AA) Modifications Resource
230Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).Swiss-Prot 53.0
249Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).Swiss-Prot 53.0
254Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).Swiss-Prot 53.0
324Phosphoserine (by MAPK1).Swiss-Prot 53.0
336Phosphothreonine (by MAPK1).Swiss-Prot 53.0
383Phosphoserine (by MAPK1).Swiss-Prot 53.0
383Phosphoserine (MAPK14;MAPK3)Phospho.ELM 6.0
389Phosphoserine (by MAPK1).Swiss-Prot 53.0
389Phosphoserine (MAPK14;MAPK3)Phospho.ELM 6.0
417Phosphothreonine (PRP4)Phospho.ELM 6.0
422Phosphoserine (by MAPK1).Swiss-Prot 53.0
Location(AA) Modification Resource
51N-linkedHMM predict
54N-linkedHMM predict
56N-linkedHMM predict
77Phosphoserine(PKA)HMM predict
77Phosphoserine(PKG)HMM predict
106O-linkedHMM predict
109O-linkedHMM predict
128O-linkedHMM predict
133Phosphothreonine(CDC2)HMM predict
153Phosphotyrosine(INSR)HMM predict
183O-linkedHMM predict
194O-linkedHMM predict
194O-linkedHMM predict
196O-linkedHMM predict
196O-linkedHMM predict
198O-linkedHMM predict
199Phosphothreonine(PKC)HMM predict
200Phosphoserine(IKK)HMM predict
200O-linkedHMM predict
200PhosphoserineHMM predict
200Phosphoserine(CDC2)HMM predict
202Phosphoserine(CDC2)HMM predict
304O-linkedHMM predict
308Phosphoserine(ATM)HMM predict
308O-linkedHMM predict
324Phosphoserine(MAPK)HMM predict
336O-linkedHMM predict
336Phosphothreonine(MAPK)HMM predict
336Phosphothreonine(CDC2)HMM predict
339O-linkedHMM predict
339Phosphoserine(IKK)HMM predict
353O-linkedHMM predict
353Phosphothreonine(CDK)HMM predict
353Phosphothreonine(MAPK)HMM predict
355O-linkedHMM predict
363Phosphothreonine(CDK)HMM predict
368Phosphothreonine(CDK)HMM predict
368Phosphothreonine(MAPK)HMM predict
370O-linkedHMM predict
371O-linkedHMM predict
383Phosphoserine(CDC2)HMM predict
389Phosphoserine(CDK)HMM predict
400Phosphoserine(CDK)HMM predict
417PhosphothreonineHMM predict
422Phosphoserine(CDK)HMM predict
422Phosphoserine(CDC2)HMM predict
422O-linkedHMM predict
428ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005229
  • Location:chrX 47379864-47394963
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 47394733 47395509 776 158
TFAP2C MCF7GSE21234 47394713 47395519 806 153
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 47378980 47379198 218 776
NRSF mAbJurkat 47377990 47378916 926 1412
Oct1 H2O2-HelaGSE14283 47379495 47379548 53 343
Oct1 HelaGSE14283 47379495 47379538 43 348
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 47389182 47389283 101 0
CTCF CD4SISSRdata 47389182 47389283 101 0
CTCF G2GSE9613 47380953 47382257 1304 0
CTCF G2GSE9613 47383264 47383632 368 0
CTCF G2GSE9613 47388270 47389551 1281 0
CTCF G2GSE9613 47393769 47394720 951 0
Fos K562GSE19551 47381950 47382165 215 0
H3K4me3 colorectalcancer 47393841 47394293 452 0
PHF8 HeLaGSE20725 47394468 47395328 860 0
hScc1 G2GSE9613 47381721 47382110 389 0
hScc1 G2GSE9613 47383290 47383632 342 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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