AutismKB 2.0

Annotation Detail for ENO1


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Basic Information Top
Gene Symbol:ENO1 ( ENO1L1,MPB1,NNE,PPH )
Gene Full Name: enolase 1, (alpha)
Band: 1p36.23
Quick LinksEntrez ID:2023; OMIM: 172430; Uniprot ID:ENOA_HUMAN; ENSEMBL ID: ENSG00000074800; HGNC ID: 3350
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine.
5N6-acetyllysine.
37Phosphoserine.
44Phosphotyrosine.
57Phosphotyrosine.
60N6-acetyllysine.
63Phosphoserine.
64N6-acetyllysine.
71N6-acetyllysine.
72Phosphothreonine.
89N6-acetyllysine.
126N6-acetyllysine.
193N6-acetyllysine.
199N6-acetyllysine.
228N6-acetyllysine.
233N6-acetyllysine.
254Phosphoserine.
256N6-acetyllysine.
263Phosphoserine.
272Phosphoserine.
281N6-acetyllysine.
285N6-acetyllysine.
287Phosphotyrosine.
390Phosphothreonine.
406N6-acetyllysine.
420N6-acetyllysine.
Location(AA) Modifications Resource
43Phosphotyrosine (Src)Phospho.ELM 6.0
44Phosphotyrosine.Swiss-Prot 53.0
71N6-acetyllysine.Swiss-Prot 53.0
263Phosphoserine (By similarity).Swiss-Prot 53.0
286PhosphotyrosinePhospho.ELM 6.0
287Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
17N-linkedHMM predict
37O-linkedHMM predict
44Phosphotyrosine(SRC)HMM predict
70N-linkedHMM predict
83N-linkedHMM predict
102N-linkedHMM predict
270Phosphotyrosine(INSR)HMM predict
272Phosphoserine(CAMK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001428
  • Location:chr1 8843649-8861366
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 8861225 8862123 898 308
ER MCF7GSE19013 8861763 8862174 411 602
ETS1 JurkatGSE17954 8860507 8862551 2044 163
FOXA1 MCF7GSE15244 8862669 8863725 1056 1831
H3ac HepG2E 8862043 8863725 1682 1518
H3ac HepG2E 8867624 8868021 397 6456
HIF1 HypoHepG2 8861082 8862043 961 196
NFkBII GM15510GSE19485 8860404 8862610 2206 141
Oct1 HelaGSE14283 8874534 8874568 34 13185
PHF8 293TGSE20725 8860454 8862471 2017 96
Pol2 GM12878GSE19551 8861084 8862408 1324 380
Rb GrowingGSE19898 8861258 8861512 254 19
Rb GrowingGSE19898 8872599 8872777 178 11322
Rb QuiescentGSE19898 8861241 8861639 398 74
TAF k562GSE8489 8862123 8862831 708 1111
USF1 HepG2E 8862043 8862781 738 1046
USF2 HepG2E 8862043 8862868 825 1089
hScc1 BcellGSE12603 8861049 8862123 1074 220
hScc1 BcellGSE12603 8876053 8876285 232 14803
p130 SenescentGSE19898 8861139 8861733 594 70
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 8831537 8831845 308 11959
CTCF CD4GSE12889 8842139 8842418 279 1371
CTCF CD4SISSRdata 8831537 8831845 308 11959
CTCF CD4SISSRdata 8842139 8842418 279 1371
CTCF JurkatGSE12889 8831495 8831828 333 11988
CTCF G2GSE9613 8831373 8832026 653 11950
Oct1 H2O2-HelaGSE14283 8826894 8826927 33 16739
Oct1 HelaGSE14283 8826896 8826944 48 16730
RARA MCF7GSE15244 8840948 8841201 253 2575
hScc1 BcellGSE12603 8828400 8828639 239 15130
hScc1 BcellGSE12603 8831373 8832026 653 11950
hScc1 CdLSGSE12603 8831373 8832026 653 11950
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 8848454 8848788 334 0
CTCF G2GSE9613 8853525 8854093 568 0
Fos K562GSE19551 8856008 8856791 783 0
H3K4me2 HCT116GSE10453 8857266 8858025 759 0
H3ac HepG2E 8854397 8854858 461 0
H3ac HepG2E 8855585 8856897 1312 0
H3ac HepG2E 8857266 8859206 1940 0
H3ac HepG2E 8860547 8861189 642 0
Myc hESGSE17917 8860656 8860860 204 0
Nanog hESGSE18292 8855996 8856437 441 0
PHF8 HeLaGSE20725 8860313 8862377 2064 0
PHF8 Hs68plusFBSGSE20725 8860003 8862408 2405 0
Pol2 GM12878GSE19551 8860415 8861061 646 0
RARA MCF7GSE15244 8856348 8856897 549 0
Rb GrowingGSE19898 8860617 8860859 242 0
Rb QuiescentGSE19898 8860585 8860803 218 0
Rb SenescentGSE19898 8860571 8860929 358 0
Rb SenescentGSE19898 8861081 8861641 560 0
Rb shRbSenescenceGSE19898 8860500 8860860 360 0
TAF k562GSE8489 8857266 8859206 1940 0
TAF k562GSE8489 8860547 8860863 316 0
USF1 HepG2E 8860547 8860828 281 0
p130 QuiescentGSE19898 8860586 8861030 444 0
p130 QuiescentGSE19898 8861134 8861473 339 0
p130 SenescentGSE19898 8860533 8860940 407 0
p130 shRbQuiescentGSE19898 8861113 8861577 464 0
p130 shRbSenescentGSE19898 8860561 8861111 550 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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