AutismKB 2.0

Annotation Detail for LGI3


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Basic Information Top
Gene Symbol:LGI3 ( LGIL4 )
Gene Full Name: leucine-rich repeat LGI family, member 3
Band: 8p21.3
Quick LinksEntrez ID:203190; OMIM: 608302; Uniprot ID:LGI3_HUMAN; ENSEMBL ID: ENSG00000168481; HGNC ID: 18711
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
189N-linked (GlcNAc...) (Potential).
311N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
189N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
311N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
49Phosphothreonine(PKA)HMM predict
189N-linkedHMM predict
190O-linkedHMM predict
246Phosphotyrosine(Jak)HMM predict
272Phosphotyrosine(EGFR)HMM predict
311N-linkedHMM predict
394O-linkedHMM predict
457Phosphoserine(PKA)HMM predict
467Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_139278
  • Location:chr8 22060289-22070288
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 22071958 22072477 519 1929
NRSF pAbJurkat 22071491 22071811 320 1363
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 22058700 22058984 284 1448
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 22060354 22060526 172 0
CTCF CD4SISSRdata 22060354 22060526 172 0
CTCF HelaGSE12889 22060294 22060478 184 0
CTCF G2GSE9613 22060107 22061402 1295 0
CTCF G2GSE9613 22061698 22061910 212 0
CTCF G2GSE9613 22062240 22062499 259 0
CTCF G2GSE9613 22065017 22065225 208 0
CTCF G2GSE9613 22067197 22067819 622 0
CTCF G2GSE9613 22069902 22070434 532 0
FOXA1 MCF7GSE15244 22061836 22062158 322 0
NRSF pAbJurkat 22063271 22063560 289 0
NRSF pAbJurkat 22067385 22068081 696 0
NRSF pAbJurkat 22069325 22069714 389 0
hScc1 BcellGSE12603 22060083 22060723 640 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018