AutismKB 2.0

Annotation Detail for NRK


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Basic Information Top
Gene Symbol:NRK ( DKFZp686A17109,FLJ16788,MGC131849,NESK )
Gene Full Name: Nik related kinase
Band: Xq22.3
Quick LinksEntrez ID:203447; OMIM: 300791; Uniprot ID:NRK_HUMAN; ENSEMBL ID: ENSG00000123572; HGNC ID: 25391
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
36Phosphotyrosine(INSR)HMM predict
61Phosphothreonine(CDK)HMM predict
61Phosphothreonine(MAPK)HMM predict
101Phosphoserine(PKC)HMM predict
117Phosphoserine(CDC2)HMM predict
276Phosphothreonine(PKC)HMM predict
356Phosphotyrosine(Jak)HMM predict
573Phosphothreonine(CK2)HMM predict
593Phosphoserine(ATM)HMM predict
654N-linkedHMM predict
655N-linkedHMM predict
664Phosphothreonine(PKC)HMM predict
675Phosphotyrosine(SRC)HMM predict
676Phosphoserine(IKK)HMM predict
690Phosphothreonine(PKC)HMM predict
753Phosphoserine(CK2)HMM predict
754Phosphoserine(CK1)HMM predict
754Phosphoserine(ATM)HMM predict
788Phosphoserine(CDC2)HMM predict
790Phosphoserine(PKB)HMM predict
790Phosphoserine(PKA)HMM predict
790Phosphoserine(IKK)HMM predict
790Phosphoserine(CK1)HMM predict
839Phosphoserine(CK2)HMM predict
840Phosphoserine(CK1)HMM predict
840Phosphoserine(CK2)HMM predict
841Phosphoserine(CK1)HMM predict
848Phosphothreonine(PKC)HMM predict
852Phosphoserine(CAMK2)HMM predict
852Phosphoserine(ATM)HMM predict
852Phosphoserine(IKK)HMM predict
852Phosphoserine(PKG)HMM predict
854PhosphoserineHMM predict
854PhosphoserineHMM predict
854Phosphoserine(PKG)HMM predict
855O-linkedHMM predict
858Phosphotyrosine(INSR)HMM predict
858Phosphotyrosine(SRC)HMM predict
920Phosphotyrosine(Jak)HMM predict
920PhosphotyrosineHMM predict
920Phosphotyrosine(EGFR)HMM predict
920SulfotyrosineHMM predict
920Phosphotyrosine(INSR)HMM predict
939N-linkedHMM predict
985Phosphotyrosine(Syk)HMM predict
1025N-linkedHMM predict
1034Phosphoserine(CAMK2)HMM predict
1069Phosphoserine(CK2)HMM predict
1082N-linkedHMM predict
1101Phosphotyrosine(EGFR)HMM predict
1101SulfotyrosineHMM predict
1118O-linkedHMM predict
1146N-linkedHMM predict
1149Phosphoserine(CDC2)HMM predict
1151Phosphoserine(CK1)HMM predict
1327Phosphotyrosine(SRC)HMM predict
1327Phosphotyrosine(EGFR)HMM predict
1327Phosphotyrosine(INSR)HMM predict
1362Phosphoserine(CK2)HMM predict
1362Phosphoserine(CK1)HMM predict
1366Phosphotyrosine(SRC)HMM predict
1366Phosphotyrosine(INSR)HMM predict
1366SulfotyrosineHMM predict
1433Phosphotyrosine(INSR)HMM predict
1482Phosphoserine(CK1)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_198465
  • Location:chrX 104953191-105089254
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 104949804 104949855 51 3362
TFAP2C MCF7GSE21234 104952194 104952845 651 672
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 104952884 104953876 992 0
CTCF G2GSE9613 105039407 105039870 463 0
Oct1 HelaGSE14283 105010265 105010339 74 0
Oct1 HelaGSE14283 105013651 105013685 34 0
Oct1 HelaGSE14283 105013843 105013873 30 0
Oct1 HelaGSE14283 105045756 105045790 34 0
Oct1 HelaGSE14283 105047134 105047161 27 0
PAX3-FKHR Rh4GSE19063 105003433 105004581 1148 0
Rb shRbQuiescentGSE19898 105061685 105061944 259 0
hScc1 G2GSE9613 105007387 105007566 179 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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