Annotation Detail for AK2
Basic Information Top
| Gene Symbol: | AK2 ( ADK2 ) |
|---|---|
| Gene Full Name: | adenylate kinase 2 |
| Band: | 1p35.1 |
| Quick Links | Entrez ID:204; OMIM: 103020; Uniprot ID:KAD2_HUMAN; ENSEMBL ID: ENSG00000004455; HGNC ID: 362 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 14 | N6-acetyllysine. | |
| 93 | N6-acetyllysine (By similarity). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 93 | N6-acetyllysine (By similarity). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 46 | Phosphothreonine(PKA) | HMM predict |
| 56 | O-linked | HMM predict |
| 67 | Phosphothreonine(PKA) | HMM predict |
| 140 | Phosphothreonine(PKA) | HMM predict |
| 195 | O-linked | HMM predict |
| 213 | Phosphoserine(ATM) | HMM predict |
| 215 | Phosphothreonine(MAPK) | HMM predict |
- RefSeq ID: NM_001625
- Location:chr1 33251169-33275057
- strand:-
| No data |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Fos | K562 | GSE19551 | 33274162 | 33275777 | 1615 | 0 |
| GABP | k562 | GSE8489 | 33273250 | 33274811 | 1561 | 0 |
| H3K4me2 | HCT116 | GSE10453 | 33273250 | 33274880 | 1630 | 0 |
| H3K4me3 | colorectal | cancer | 33273902 | 33274848 | 946 | 0 |
| H3ac | HepG2 | E | 33273250 | 33274913 | 1663 | 0 |
| Oct1 | Hela | GSE14283 | 33254289 | 33254358 | 69 | 0 |
| Oct1 | Hela | GSE14283 | 33265303 | 33265335 | 32 | 0 |
| P300 | T30-glioblastoma | GSE21026 | 33274300 | 33275665 | 1365 | 0 |
| PHF8 | HeLa | GSE20725 | 33274377 | 33275504 | 1127 | 0 |
| TAF | Hela | GSE8489 | 33273939 | 33274880 | 941 | 0 |
| TAF | k562 | GSE8489 | 33273250 | 33275343 | 2093 | 0 |
| TFAP2C | MCF7 | GSE21234 | 33263390 | 33263792 | 402 | 0 |
| c | MYC | MCF7 | 33274228 | 33274880 | 652 | 0 |
| hScc1 | Bcell | GSE12603 | 33274630 | 33275320 | 690 | 0 |
| p130 | shRbSenescent | GSE19898 | 33274705 | 33275010 | 305 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-1 | hsa-mir-1-2 | 18 | 15685193 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 15685193 |
| hsa-miR-124 | hsa-mir-124-1 | 8 | 15685193 |
| hsa-miR-124 | hsa-mir-124-2 | 8 | 15685193 |
| hsa-miR-124 | hsa-mir-124-3 | 20 | 15685193 |
| hsa-miR-373 | hsa-mir-373 | 19 | 15685193 |
| hsa-miR-373* | hsa-mir-373 | 19 | 15685193 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 322 | Unknown | MicroArray | miR-124 | AK2 | n_a | 15685193 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000004455 | G1-to-S transition | n_a | n_a | "adipocyte, lymphoblast, lymphocyte, muscle cell" | "benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma" |
| Cluster ID | Plue Type | Plus Gene Name | Plus Chromosome | Plus Start | Plus End | Overlap Length | Minus Type | Minus Gene Name | Minus Chromosome | Minus Star | Minus End | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 545 | HTC | chr1 | 33121768 | 33167163 | 118 | mRNA | AK2 | chr1 | 33148050 | 33171525 | Sense/Antisense (SA) pairs | |