AutismKB 2.0

Annotation Detail for EPHA5


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Basic Information Top
Gene Symbol:EPHA5 ( CEK7,EHK1,HEK7,TYRO4 )
Gene Full Name: EPH receptor A5
Band: 4q13.1-q13.2
Quick LinksEntrez ID:2044; OMIM: 600004; Uniprot ID:EPHA5_HUMAN; ENSEMBL ID: ENSG00000145242; HGNC ID: 3389
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
264N-linked (GlcNAc...) (Potential).
299N-linked (GlcNAc...) (Potential).
369N-linked (GlcNAc...) (Potential).
423N-linked (GlcNAc...) (Potential).
436N-linked (GlcNAc...) (Potential).
461N-linked (GlcNAc...) (Potential).
650Phosphotyrosine; by autocatalysis (By
656Phosphotyrosine; by autocatalysis (By
833Phosphotyrosine; by autocatalysis
982Phosphotyrosine; by autocatalysis (By
1037PDZ-binding (Potential).
Location(AA) Modifications Resource
264N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
299N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
369N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
423N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
436N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
461N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
650Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
656Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
833Phosphotyrosine (by autocatalysis)(Potential).Swiss-Prot 53.0
982Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
Location(AA) Modification Resource
16O-linkedHMM predict
24Phosphothreonine(MAPK)HMM predict
24Phosphothreonine(CDK)HMM predict
56Phosphoserine(CDC2)HMM predict
139Phosphoserine(CK1)HMM predict
171Phosphotyrosine(INSR)HMM predict
253Phosphoserine(ATM)HMM predict
264N-linkedHMM predict
299N-linkedHMM predict
328Phosphothreonine(CDK)HMM predict
347Phosphoserine(PKG)HMM predict
355O-linkedHMM predict
369N-linkedHMM predict
414Phosphotyrosine(Jak)HMM predict
436N-linkedHMM predict
461N-linkedHMM predict
465N-linkedHMM predict
470Phosphoserine(CDC2)HMM predict
486Phosphoserine(CK1)HMM predict
597Phosphoserine(IKK)HMM predict
601S-palmitoylHMM predict
608Phosphoserine(PKB)HMM predict
608Phosphoserine(IKK)HMM predict
656PhosphotyrosineHMM predict
656Phosphotyrosine(Syk)HMM predict
656Phosphotyrosine(INSR)HMM predict
656Phosphotyrosine(SRC)HMM predict
744Phosphothreonine(PKC)HMM predict
758N-linkedHMM predict
796Phosphotyrosine(Jak)HMM predict
856Phosphothreonine(PKA)HMM predict
857Phosphoserine(PKA)HMM predict
938N-linkedHMM predict
960Phosphoserine(IKK)HMM predict
991Phosphotyrosine(SRC)HMM predict
991Phosphotyrosine(INSR)HMM predict
992Phosphoserine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004439
  • Location:chr4 65872240-66218103
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 66218576 66219218 642 794
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 66216633 66217863 1230 0
ER E2-MCF7GSE14664 66141650 66141743 93 0
ER MCF7GSE19013 65965090 65965541 451 0
H3K27me3 colorectalcancer 66216096 66217825 1729 0
H3ac HepG2E 66121766 66122088 322 0
Nanog hESGSE18292 65999186 65999506 320 0
Oct1 H2O2-HelaGSE14283 66111635 66111666 31 0
Oct1 H2O2-HelaGSE14283 66117682 66117746 64 0
Oct1 H2O2-HelaGSE14283 66139067 66139095 28 0
Oct1 HelaGSE14283 66111635 66111666 31 0
Oct1 HelaGSE14283 66117682 66117736 54 0
Oct1 HelaGSE14283 66139066 66139095 29 0
Oct1 HelaGSE14283 66184377 66184417 40 0
P300 T30-glioblastomaGSE21026 66056232 66057141 909 0
STAT1 HeLaGSE12782 66198677 66199919 1242 0
STAT1 HeLaGSE12783 66198677 66199919 1242 0
TAF HelaGSE8489 66121766 66122124 358 0
hScc1 BcellGSE12603 66217449 66217794 345 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
19737 mRNA chr4 66364444 66387869 535 mRNA EPHA5 chr4 66025044 66364979Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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