AutismKB 2.0

Annotation Detail for EPHB6


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Basic Information Top
Gene Symbol:EPHB6 ( HEP,MGC129910,MGC129911 )
Gene Full Name: EPH receptor B6
Band: 7q34
Quick LinksEntrez ID:2051; OMIM: 602757; Uniprot ID:EPHB6_HUMAN; ENSEMBL ID: ENSG00000106123; HGNC ID: 3396
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
480N-linked (GlcNAc...) (Potential).
1021PDZ-binding (Potential).
Location(AA) Modifications Resource
465N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
54Phosphothreonine(PKA)HMM predict
54Phosphothreonine(PKC)HMM predict
125Phosphoserine(IKK)HMM predict
125PhosphoserineHMM predict
125Phosphoserine(MAPK)HMM predict
125Phosphoserine(CDC2)HMM predict
148Phosphoserine(IKK)HMM predict
159Phosphoserine(CK1)HMM predict
160Phosphoserine(CK1)HMM predict
226Phosphoserine(IKK)HMM predict
233O-linkedHMM predict
319S-palmitoylHMM predict
323O-linkedHMM predict
344Phosphoserine(PKB)HMM predict
426Phosphothreonine(PKC)HMM predict
455O-linkedHMM predict
465N-linkedHMM predict
467O-linkedHMM predict
474O-linkedHMM predict
492Phosphoserine(IKK)HMM predict
511Phosphotyrosine(EGFR)HMM predict
511SulfotyrosineHMM predict
520Phosphoserine(IKK)HMM predict
524O-linkedHMM predict
529O-linkedHMM predict
572Phosphoserine(ATM)HMM predict
611Phosphothreonine(PKA)HMM predict
622Phosphoserine(CDC2)HMM predict
622Phosphoserine(ATM)HMM predict
636Phosphotyrosine(Syk)HMM predict
654Phosphotyrosine(INSR)HMM predict
654Phosphotyrosine(EGFR)HMM predict
724Phosphothreonine(PKC)HMM predict
802Phosphoserine(CDC2)HMM predict
802Phosphoserine(CDK)HMM predict
847Phosphotyrosine(Syk)HMM predict
926Phosphothreonine(MAPK)HMM predict
953N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004445
  • Location:chr7 142262913-142278966
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 142243525 142243654 129 19324
CTCF CD4GSE12889 142261816 142262148 332 932
CTCF CD4SISSRdata 142243525 142243654 129 19324
CTCF CD4SISSRdata 142261816 142262148 332 932
CTCF G2GSE9613 142261593 142262371 778 932
Myc K562GSE19551 142246346 142246762 416 16360
hScc1 BcellGSE12603 142261593 142263014 1421 610
hScc1 CdLSGSE12603 142261593 142262227 634 1004
hScc1 G2GSE9613 142261631 142263313 1682 442
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 142262749 142263313 564 0
CTCF G2GSE9613 142271619 142271789 170 0
CTCF G2GSE9613 142274036 142274914 878 0
CTCF G2GSE9613 142275438 142276161 723 0
CTCF G2GSE9613 142278541 142278987 446 0
ER MCF7GSE19013 142267781 142268470 689 0
Oct1 HelaGSE14283 142277666 142277749 83 0
Rb shRbQuiescentGSE19898 142273428 142273587 159 0
TFAP2C MCF7GSE21234 142263595 142264134 539 0
TFAP2C MCF7GSE21234 142264585 142264998 413 0
hScc1 CdLSGSE12603 142274156 142274625 469 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-181a hsa-mir-181a-2 9 20576283
hsa-miR-181a hsa-mir-181a-1 1 20576283
hsa-miR-181a-2* hsa-mir-181a-2 9 20576283
hsa-miR-491-5p hsa-mir-491 9 20015148
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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