AutismKB 2.0

Annotation Detail for EPHX2


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Basic Information Top
Gene Symbol:EPHX2 ( CEH,SEH )
Gene Full Name: epoxide hydrolase 2, cytoplasmic
Band: 8p21.2-p21.1
Quick LinksEntrez ID:2053; OMIM: 132811; Uniprot ID:HYES_HUMAN; ENSEMBL ID: ENSG00000120915; HGNC ID: 3402
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
43N6-acetyllysine.
555Microbody targeting signal (Potential).
Location(AA) Modifications Resource
Location(AA) Modification Resource
176Phosphoserine(CDC2)HMM predict
230O-linkedHMM predict
231Phosphoserine(IKK)HMM predict
233N-linkedHMM predict
241Phosphotyrosine(Jak)HMM predict
243Phosphothreonine(PKC)HMM predict
327Phosphoserine(ATM)HMM predict
412Phosphoserine(CK2)HMM predict
415Phosphoserine(IKK)HMM predict
432Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001979
  • Location:chr8 27404561-27458400
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Gata2 K562GSE18868 27402166 27402749 583 2104
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 27473661 27473866 205 15363
CTCF G2GSE9613 27474770 27474992 222 16481
NRSF pAbJurkat 27473304 27473828 524 15166
Oct1 HelaGSE14283 27469373 27469407 34 10990
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 27403756 27406614 2858 0
CTCF CD4GSE12889 27429386 27429638 252 0
CTCF CD4SISSRdata 27429386 27429638 252 0
CTCF G2GSE9613 27457762 27458452 690 0
Myc K562GSE19551 27429144 27429721 577 0
Myc K562GSE19551 27437650 27438073 423 0
Oct1 H2O2-HelaGSE14283 27423814 27423851 37 0
Oct1 HelaGSE14283 27440486 27440545 59 0
PHF8 HeLaGSE20725 27404209 27405161 952 0
hScc1 BcellGSE12603 27425136 27425260 124 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018