Annotation Detail for ERCC4

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Basic Information Top

Gene Symbol:	ERCC4 ( ERCC11,RAD1,XPF )
Gene Full Name:	excision repair cross-complementing rodent repair deficiency, complementation group 4
Band:	16p13.12
Quick Links	Entrez ID:2072; OMIM: 133520; Uniprot ID:XPF_HUMAN; ENSEMBL ID: ENSG00000175595; HGNC ID: 3436
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
289	N6-acetyllysine.
491	Nuclear localization signal (Potential).
520	Phosphoserine.
521	Phosphoserine.
524	Phosphoserine.

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	CD4	GSE12889	13920997	13921591	594	230
CTCF	CD4	SISSRdata	13920997	13921591	594	230
CTCF	Hela	GSE12889	13921064	13921448	384	268
CTCF	G2	GSE9613	13920724	13921760	1036	282
LIN9	G0	GSE7516	13920760	13921367	607	460
LIN9	S	GSE7516	13920724	13921194	470	565
Nanog	hES	GSE18292	13912339	13912957	618	8876
PHF8	HeLa	GSE20725	13921002	13921998	996	24
TFAP2C	MCF7	GSE21234	13914679	13915277	598	6546
hScc1	Bcell	GSE12603	13920980	13921546	566	261
hScc1	CdLS	GSE12603	13920724	13921476	752	424

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
FOXA1	MCF7	GSE15244	13958399	13959452	1053	9222
FoxA1	MCF7	MACSdata	13959244	13959420	176	9629
Nanog	ES	GSE20650	13966009	13966136	127	16369
RARA	MCF7	GSE15244	13958337	13959524	1187	9227
TFAP2C	MCF7	GSE21234	13958490	13959704	1214	9394

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	CD4	GSE12889	13936836	13937031	195
CTCF	CD4	SISSRdata	13936836	13937031	195
CTCF	G2	GSE9613	13925246	13925577	331
CTCF	G2	GSE9613	13936678	13937119	441
ER	Fulvestrant-MCF7	GSE14664	13943392	13943426	34
H3K4me3	colorectal	cancer	13921933	13922764	831
H3ac	HepG2	E	13921841	13923055	1214
NRSF	Jurkat	SISSRdata	13921556	13921751	195
Oct1	Hela	GSE14283	13943388	13943426	38
TFAP2C	MCF7	GSE21234	13939538	13940055	517
hScc1	Bcell	GSE12603	13925246	13925650	404
hScc1	CdLS	GSE12603	13925246	13925577	331
p130	Senescent	GSE19898	13921331	13921987	656
p130	shRbQuiescent	GSE19898	13921529	13922156	627

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-let-7g	hsa-let-7g	3	21293479
hsa-let-7g	hsa-let-7g	3	21293479
hsa-let-7g*	hsa-let-7g	3	21293479
hsa-let-7g*	hsa-let-7g	3	21293479
hsa-miR-126	hsa-mir-126	9	21293479
hsa-miR-126	hsa-mir-126	9	21293479
hsa-miR-126*	hsa-mir-126	9	21293479
hsa-miR-126*	hsa-mir-126	9	21293479
hsa-miR-196a	hsa-mir-196a-1	17	21293479
hsa-miR-196a	hsa-mir-196a-2	12	21293479
hsa-miR-196a	hsa-mir-196a-1	17	21293479
hsa-miR-196a	hsa-mir-196a-2	12	21293479
hsa-miR-31	hsa-mir-31	9	21293479
hsa-miR-31	hsa-mir-31	9	21293479
hsa-miR-31*	hsa-mir-31	9	21293479
hsa-miR-31*	hsa-mir-31	9	21293479
hsa-miR-338-3p	hsa-mir-338	17	21293479
hsa-miR-338-3p	hsa-mir-338	17	21293479
hsa-miR-338-5p	hsa-mir-338	17	21293479
hsa-miR-338-5p	hsa-mir-338	17	21293479
hsa-miR-7	hsa-mir-7-1	9	21293479
hsa-miR-7	hsa-mir-7-2	15	21293479
hsa-miR-7	hsa-mir-7-3	19	21293479
hsa-miR-7	hsa-mir-7-1	9	21293479
hsa-miR-7	hsa-mir-7-2	15	21293479
hsa-miR-7	hsa-mir-7-3	19	21293479
hsa-miR-98	hsa-mir-98	X	21293479
hsa-miR-98	hsa-mir-98	X	21293479

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
9644	mRNA	ERCC4	chr16	13921523	13949705	363	EST		chr16	13932034	13936993	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018