AutismKB 2.0

Annotation Detail for ERF


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ERF ( PE-2,PE2 )
Gene Full Name: Ets2 repressor factor
Band: 19q13.2
Quick LinksEntrez ID:2077; OMIM: 611888; Uniprot ID:ERF_HUMAN; ENSEMBL ID: ENSG00000105722; HGNC ID: 3444
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
3Phosphothreonine.
7Phosphothreonine.
16Phosphotyrosine.
20Phosphoserine.
21Phosphoserine.
148Phosphothreonine.
171Phosphoserine.
185Phosphoserine.
187Phosphoserine.
190Phosphoserine.
327Phosphoserine.
431Phosphoserine.
435Phosphoserine.
441Phosphothreonine.
444Phosphoserine.
526Phosphothreonine; by MAPK1.
531Phosphoserine.
548Phosphoserine.
Location(AA) Modifications Resource
21Phosphoserine.Swiss-Prot 53.0
161Phosphoserine (MAPK1)Phospho.ELM 6.0
185Phosphoserine.Swiss-Prot 53.0
187Phosphoserine.Swiss-Prot 53.0
190Phosphoserine.Swiss-Prot 53.0
246Phosphoserine (MAPK1)Phospho.ELM 6.0
251Phosphoserine (MAPK1)Phospho.ELM 6.0
526Phosphothreonine (by MAPK1).Swiss-Prot 53.0
526Phosphothreonine (MAPK1)Phospho.ELM 6.0
531Phosphoserine.Swiss-Prot 53.0
531PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
103Phosphothreonine(PKC)HMM predict
131O-linkedHMM predict
148Phosphothreonine(MAPK)HMM predict
150O-linkedHMM predict
154Phosphoserine(MAPK)HMM predict
156O-linkedHMM predict
161O-linkedHMM predict
161Phosphoserine(IKK)HMM predict
194Phosphoserine(CK2)HMM predict
239MethylarginineHMM predict
246Phosphoserine(CDC2)HMM predict
246O-linkedHMM predict
251Phosphoserine(CDC2)HMM predict
271O-linkedHMM predict
271Phosphothreonine(CDK)HMM predict
271Phosphothreonine(MAPK)HMM predict
278O-linkedHMM predict
278Phosphothreonine(MAPK)HMM predict
278Phosphothreonine(CDK)HMM predict
280Phosphoserine(CDK)HMM predict
282O-linkedHMM predict
284O-linkedHMM predict
295O-linkedHMM predict
297O-linkedHMM predict
306Phosphoserine(ATM)HMM predict
357PhosphothreonineHMM predict
363Phosphoserine(IKK)HMM predict
363O-linkedHMM predict
373Phosphoserine(CDC2)HMM predict
373Phosphoserine(ATM)HMM predict
456Phosphothreonine(CDC2)HMM predict
489Phosphoserine(PKA)HMM predict
526Phosphothreonine(CDC2)HMM predict
526Phosphothreonine(MAPK)HMM predict
531Phosphoserine(PKG)HMM predict
531Phosphoserine(PKA)HMM predict
531Phosphoserine(PKA)HMM predict
531Phosphoserine(PKA)HMM predict
532Phosphoserine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006494
  • Location:chr19 47443561-47451112
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 47464149 47465538 1389 13731
FOXA1 MCF7GSE15244 47463836 47465142 1306 13377
FoxA1 MCF7MACSdata 47464694 47464863 169 13666
H3ac HepG2E 47463499 47464063 564 12669
P300 T0-glioblastomaGSE21026 47464207 47465663 1456 13823
P300 T30-glioblastomaGSE21026 47463924 47465638 1714 13669
USF1 HepG2E 47463499 47465011 1512 13143
USF2 HepG2E 47464218 47464982 764 13488
VDR GM10861-stimGSE22484 47453091 47454157 1066 2512
p130 QuiescentGSE19898 47451075 47451306 231 78
p130 shRbQuiescentGSE19898 47451843 47452357 514 988
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 47441903 47442261 358 1480
Oct1 HelaGSE14283 47442083 47442113 30 1464
Rb shRbSenescenceGSE19898 47441950 47442139 189 1517
p130 SenescentGSE19898 47443145 47443465 320 257
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PolII HeLaGSE12783 47448464 47452269 3805 0
Rb QuiescentGSE19898 47449363 47449531 168 0
TFAP2C MCF7GSE21234 47447444 47448098 654 0
hScc1 BcellGSE12603 47444336 47445032 696 0
hScc1 BcellGSE12603 47449413 47449886 473 0
hScc1 BcellGSE12603 47450451 47450986 535 0
p130 QuiescentGSE19898 47448441 47448843 402 0
p130 QuiescentGSE19898 47449281 47449528 247 0
p130 QuiescentGSE19898 47450080 47450282 202 0
p130 SenescentGSE19898 47448411 47449068 657 0
p130 SenescentGSE19898 47450036 47450310 274 0
p130 shRbQuiescentGSE19898 47448424 47448864 440 0
p130 shRbQuiescentGSE19898 47449162 47449603 441 0
p130 shRbSenescentGSE19898 47448318 47448830 512 0
p130 shRbSenescentGSE19898 47449224 47449576 352 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-7 hsa-mir-7-1 9 20978205
hsa-miR-7 hsa-mir-7-2 15 20978205
hsa-miR-7 hsa-mir-7-3 19 20978205
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved