AutismKB 2.0

Annotation Detail for ESRRA


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Basic Information Top
Gene Symbol:ESRRA ( ERR1,ERRa,ERRalpha,ESRL1,NR3B1 )
Gene Full Name: estrogen-related receptor alpha
Band: 11q13.1
Quick LinksEntrez ID:2101; OMIM: 601998; Uniprot ID:ERR1_HUMAN; ENSEMBL ID: ENSG00000173153; HGNC ID: 3471
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
19Phosphoserine.
22Phosphoserine.
26Phosphoserine.
27Phosphoserine.
Location(AA) Modifications Resource
116Phosphoserine (By similarity).Swiss-Prot 53.0
119Phosphoserine.Swiss-Prot 53.0
119PhosphoserinePhospho.ELM 6.0
124Phosphoserine.Swiss-Prot 53.0
124PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
10Phosphoserine(IKK)HMM predict
10Phosphoserine(CDC2)HMM predict
53MethylarginineHMM predict
73O-linkedHMM predict
87O-linkedHMM predict
96O-linkedHMM predict
100Phosphoserine(ATM)HMM predict
116Phosphoserine(CDC2)HMM predict
116Phosphoserine(MAPK)HMM predict
116Phosphoserine(IKK)HMM predict
116Phosphoserine(ATM)HMM predict
119Phosphoserine(IKK)HMM predict
119Phosphoserine(CDC2)HMM predict
210Phosphotyrosine(INSR)HMM predict
210Phosphotyrosine(Jak)HMM predict
306Phosphotyrosine(Abl)HMM predict
306Phosphotyrosine(Syk)HMM predict
349Phosphoserine(CK1)HMM predict
355Phosphoserine(IKK)HMM predict
355Phosphoserine(CK1)HMM predict
422Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004451
  • Location:chr11 63829619-63840785
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Breast-CancerGSE22609 63828528 63829307 779 702
FOXA1 MCF7GSE15244 63828234 63828994 760 1006
PHF8 293TGSE20725 63828362 63829292 930 793
RARA MCF7GSE15244 63828415 63828877 462 974
RARG MCF7GSE15244 63828195 63828994 799 1025
Rb GrowingGSE19898 63829248 63829385 137 303
Rb QuiescentGSE19898 63828907 63829073 166 630
Rb SenescentGSE19898 63828759 63829013 254 734
Rb SenescentGSE19898 63829085 63829451 366 352
hScc1 BcellGSE12603 63828195 63829534 1339 755
hScc1 CdLSGSE12603 63828234 63828804 570 1101
p130 QuiescentGSE19898 63829110 63829424 314 353
p130 SenescentGSE19898 63828667 63829084 417 744
p130 shRbSenescentGSE19898 63828828 63829456 628 478
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 63829156 63830623 1467 0
FOXA1 MCF7GSE15244 63830431 63831214 783 0
H3ac HepG2E 63830110 63830987 877 0
H3ac HepG2E 63836496 63837745 1249 0
NRSF pAbJurkat 63837673 63838366 693 0
TFAP2C MCF7GSE21234 63834968 63835479 511 0
TFAP2C MCF7GSE21234 63838396 63838943 547 0
USF1 HepG2E 63830299 63830649 350 0
hScc1 BcellGSE12603 63829999 63830431 432 0
hScc1 BcellGSE12603 63837745 63838132 387 0
hScc1 CdLSGSE12603 63829251 63830573 1322 0
p130 shRbSenescentGSE19898 63830426 63830876 450 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
4652 mRNA ESRRA chr11 63829619 63840786 44 mRNA HSPC152 chr11 63840742 63841609Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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