Annotation Detail for ALAS1
Basic Information Top
| Gene Symbol: | ALAS1 ( ALAS,ALAS3,ALASH,MIG4 ) |
|---|---|
| Gene Full Name: | aminolevulinate, delta-, synthase 1 |
| Band: | 3p21.2 |
| Quick Links | Entrez ID:211; OMIM: 125290; Uniprot ID:HEM1_HUMAN; ENSEMBL ID: ENSG00000023330; HGNC ID: 396 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 445 | N6-(pyridoxal phosphate)lysine | |
| Location(AA) | Modifications | Resource |
|---|
| Location(AA) | Modification | Resource |
|---|---|---|
| 49 | Phosphoserine(PKG) | HMM predict |
| 78 | Phosphothreonine(MAPK) | HMM predict |
| 78 | O-linked | HMM predict |
| 82 | Phosphoserine(ATM) | HMM predict |
| 85 | Phosphoserine(IKK) | HMM predict |
| 101 | O-linked | HMM predict |
| 104 | O-linked | HMM predict |
| 152 | O-linked | HMM predict |
| 236 | Phosphoserine(CK1) | HMM predict |
| 246 | Phosphoserine(PKA) | HMM predict |
| 253 | Phosphotyrosine(INSR) | HMM predict |
| 253 | Phosphotyrosine(Syk) | HMM predict |
| 282 | N-linked | HMM predict |
| 316 | N-linked | HMM predict |
| 422 | Methylarginine | HMM predict |
| 554 | Phosphotyrosine(EGFR) | HMM predict |
| 575 | O-linked | HMM predict |
| 575 | Phosphothreonine(MAPK) | HMM predict |
| 627 | Phosphoserine(PKB) | HMM predict |
- RefSeq ID: NM_000688
- Location:chr3 52207183-52223382
- strand:+
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| CTCF | G2 | GSE9613 | 52224469 | 52224804 | 335 | 1254 |
| FOXA1 | MCF7 | GSE15244 | 52225838 | 52226277 | 439 | 2675 |
| RARA | MCF7 | GSE15244 | 52225659 | 52226277 | 618 | 2586 |
| RARG | MCF7 | GSE15244 | 52225596 | 52226244 | 648 | 2538 |
| Rb | Growing | GSE19898 | 52225683 | 52225816 | 133 | 2367 |
| hScc1 | Bcell | GSE12603 | 52224538 | 52224988 | 450 | 1381 |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| ER | Fulvestrant-MCF7 | GSE14664 | 52212284 | 52212316 | 32 | 0 |
| FOXA1 | MCF7 | GSE15244 | 52213470 | 52214044 | 574 | 0 |
| FOXA1 | MCF7 | GSE15244 | 52220205 | 52220718 | 513 | 0 |
| FoxA1 | MCF7 | MACSdata | 52213489 | 52213649 | 160 | 0 |
| H3K4me3 | colorectal | cancer | 52207462 | 52208840 | 1378 | 0 |
| H3ac | HepG2 | E | 52207362 | 52208840 | 1478 | 0 |
| NFkBII | GM15510 | GSE19485 | 52206499 | 52207942 | 1443 | 0 |
| Oct1 | H2O2-Hela | GSE14283 | 52212284 | 52212318 | 34 | 0 |
| Oct1 | Hela | GSE14283 | 52212284 | 52212319 | 35 | 0 |
| Oct1 | Hela | GSE14283 | 52216852 | 52216911 | 59 | 0 |
| PHF8 | HeLa | GSE20725 | 52206645 | 52207886 | 1241 | 0 |
| RARA | MCF7 | GSE15244 | 52219052 | 52219347 | 295 | 0 |
| RARG | MCF7 | GSE15244 | 52207925 | 52208440 | 515 | 0 |
| hScc1 | CdLS | GSE12603 | 52206872 | 52207737 | 865 | 0 |
| p130 | Senescent | GSE19898 | 52223079 | 52223244 | 165 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-miR-1 | hsa-mir-1-2 | 18 | 19440340 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 19440340 |
| hsa-miR-107 | hsa-mir-107 | 10 | 19440340 |
| hsa-miR-133a | hsa-mir-133a-1 | 18 | 19440340 |
| hsa-miR-133a | hsa-mir-133a-2 | 20 | 19440340 |
| hsa-miR-133b | hsa-mir-133b | 6 | 19440340 |
| hsa-miR-181a | hsa-mir-181a-2 | 9 | 19440340 |
| hsa-miR-181a | hsa-mir-181a-1 | 1 | 19440340 |
| hsa-miR-181a* | hsa-mir-181a-1 | 1 | 19440340 |
| hsa-miR-181a-2* | hsa-mir-181a-2 | 9 | 19440340 |
| hsa-miR-181b | hsa-mir-181b-1 | 1 | 19440340 |
| hsa-miR-181b | hsa-mir-181b-2 | 9 | 19440340 |
| hsa-miR-181c | hsa-mir-181c | 19 | 19440340 |
| hsa-miR-181c* | hsa-mir-181c | 19 | 19440340 |
| hsa-miR-181d | hsa-mir-181d | 19 | 19440340 |
| hsa-miR-23a | hsa-mir-23a | 19 | 19440340 |
| hsa-miR-23a* | hsa-mir-23a | 19 | 19440340 |
| hsa-miR-23b | hsa-mir-23b | 9 | 19440340 |
| hsa-miR-23b* | hsa-mir-23b | 9 | 19440340 |
| No data |
Cis-Nats regulation