AutismKB 2.0

Annotation Detail for ETS1


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Basic Information Top
Gene Symbol:ETS1 ( ETS-1,EWSR2,FLJ10768 )
Gene Full Name: v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
Band: 11q24.3
Quick LinksEntrez ID:2113; OMIM: 164720; Uniprot ID:ETS1_HUMAN; ENSEMBL ID: ENSG00000134954; HGNC ID: 3488
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N6-acetyllysine.
8N6-acetyllysine.
15N6-acetyllysine.
38Phosphothreonine; by MAPK (By
205Phosphotyrosine.
223Phosphotyrosine.
270Phosphoserine.
285Phosphoserine.
305N6-acetyllysine.
Location(AA) Modifications Resource
15Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO) (Bysimilarity).Swiss-Prot 53.0
38Phosphothreonine (by MAPK) (Bysimilarity).Swiss-Prot 53.0
38Phosphothreonine (MAPK7;MAPK
205PhosphotyrosinePhospho.ELM 6.0
205Phosphotyrosine.Swiss-Prot 53.0
223Phosphotyrosine.Swiss-Prot 53.0
223PhosphotyrosinePhospho.ELM 6.0
227Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO) (Bysimilarity).Swiss-Prot 53.0
251Phosphoserine (CaM-KIIalpha)Phospho.ELM 6.0
257Phosphoserine (CaM-KIIalpha)Phospho.ELM 6.0
282Phosphoserine (CaM-KIIalpha)Phospho.ELM 6.0
285Phosphoserine (CaM-KIIalpha)Phospho.ELM 6.0
Location(AA) Modification Resource
38Phosphothreonine(MAPK)HMM predict
75Phosphothreonine(CDK)HMM predict
149Phosphotyrosine(EGFR)HMM predict
192PhosphoserineHMM predict
198Phosphoserine(MAPK)HMM predict
205Phosphotyrosine(EGFR)HMM predict
260PhosphoserineHMM predict
267Phosphoserine(IKK)HMM predict
270Phosphoserine(ATM)HMM predict
273Phosphoserine(IKK)HMM predict
282Phosphoserine(PKC)HMM predict
291Phosphotyrosine(Syk)HMM predict
424Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005238
  • Location:chr11 127833871-127897370
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
KLF4 hESGSE17917 127897331 127897707 376 149
Sox2 hESGSE18292 127907691 127908278 587 10614
hScc1 BcellGSE12603 127897155 127897978 823 196
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Rb shRbQuiescentGSE19898 127828894 127829181 287 4834
hScc1 BcellGSE12603 127829885 127830069 184 3895
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 127845952 127856228 10276 0
FOXA1 DLD1GSE12801 127882121 127882651 530 0
H3K4me3 colorectalcancer 127896164 127896961 797 0
P300 T0-glioblastomaGSE21026 127855858 127857063 1205 0
P300 T30-glioblastomaGSE21026 127842265 127843330 1065 0
P300 T30-glioblastomaGSE21026 127855862 127857068 1206 0
hScc1 BcellGSE12603 127847098 127847629 531 0
hScc1 BcellGSE12603 127895754 127896053 299 0
hScc1 CdLSGSE12603 127846959 127847460 501 0
p130 QuiescentGSE19898 127872845 127873258 413 0
p130 SenescentGSE19898 127872609 127873272 663 0
p130 SenescentGSE19898 127875027 127875411 384 0
p130 shRbQuiescentGSE19898 127872551 127873258 707 0
p130 shRbSenescentGSE19898 127842805 127843193 388 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-126 hsa-mir-126 9 20671229
hsa-miR-126* hsa-mir-126 9 20671229
hsa-miR-141 hsa-mir-141 12 20576608
hsa-miR-141* hsa-mir-141 12 20576608
hsa-miR-155 hsa-mir-155 21 21310411
hsa-miR-155 hsa-mir-155 21 19956200
hsa-miR-155 hsa-mir-155 21 18950466
hsa-miR-155* hsa-mir-155 21 21310411
hsa-miR-155* hsa-mir-155 21 19956200
hsa-miR-155* hsa-mir-155 21 18950466
hsa-miR-15a hsa-mir-15a 13 18362358
hsa-miR-15a* hsa-mir-15a 13 18362358
hsa-miR-16 hsa-mir-16-1 13 18362358
hsa-miR-16 hsa-mir-16-2 3 18362358
hsa-miR-16-1* hsa-mir-16-1 13 18362358
hsa-miR-193b hsa-mir-193b 16 20655737
hsa-miR-193b* hsa-mir-193b 16 20655737
hsa-miR-196a hsa-mir-196a-1 17 20480203
hsa-miR-196a hsa-mir-196a-2 12 20480203
hsa-miR-196a* hsa-mir-196a-2 12 20480203
hsa-miR-200b hsa-mir-200b 1 21081489
hsa-miR-200b* hsa-mir-200b 1 21081489
hsa-miR-21 hsa-mir-21 17 20427269
hsa-miR-21* hsa-mir-21 17 20427269
hsa-miR-221 hsa-mir-221 X 21310411
hsa-miR-221* hsa-mir-221 X 21310411
hsa-miR-222 hsa-mir-222 X 21310411
hsa-miR-222 hsa-mir-222 X 19956200
hsa-miR-222* hsa-mir-222 X 21310411
hsa-miR-222* hsa-mir-222 X 19956200
hsa-miR-31 hsa-mir-31 9 20427269
hsa-miR-31* hsa-mir-31 9 20427269
hsa-miR-326 hsa-mir-326 11 19838199
hsa-miR-424 hsa-mir-424 X 19956200
hsa-miR-424* hsa-mir-424 X 19956200
hsa-miR-503 hsa-mir-503 X 19956200
hsa-miR-9 hsa-mir-9-1 1 19956200
hsa-miR-9 hsa-mir-9-2 5 19956200
hsa-miR-9 hsa-mir-9-3 15 19956200
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018