AutismKB 2.0

Annotation Detail for ETS2


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Basic Information Top
Gene Symbol:ETS2 ( ETS2IT1 )
Gene Full Name: v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
Band: 21q22.2
Quick LinksEntrez ID:2114; OMIM: 164740; Uniprot ID:ETS2_HUMAN; ENSEMBL ID: ENSG00000157557; HGNC ID: 3489
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
295Phosphoserine.
Location(AA) Modifications Resource
72Phosphothreonine (MAP3K1)Phospho.ELM 6.0
Location(AA) Modification Resource
22Phosphothreonine(PKC)HMM predict
174Phosphothreonine(CK2)HMM predict
178Phosphotyrosine(INSR)HMM predict
178Phosphotyrosine(SRC)HMM predict
178Phosphotyrosine(Syk)HMM predict
186Phosphoserine(CK1)HMM predict
205Phosphotyrosine(Abl)HMM predict
228Phosphoserine(IKK)HMM predict
228O-linkedHMM predict
231Phosphoserine(CK1)HMM predict
245Phosphoserine(CK1)HMM predict
246Phosphoserine(PKB)HMM predict
250O-linkedHMM predict
268N-linkedHMM predict
269N-linkedHMM predict
291Phosphoserine(IKK)HMM predict
291Phosphoserine(CK1)HMM predict
295Phosphoserine(IKK)HMM predict
310Phosphoserine(PKC)HMM predict
313Phosphoserine(CK2)HMM predict
319Phosphoserine(ATM)HMM predict
334Phosphotyrosine(INSR)HMM predict
334SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005239
  • Location:chr21 39099718-39118745
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 39081090 39081939 849 18204
CTCF G2GSE9613 39098587 39099994 1407 428
FOXA1 MCF7GSE15244 39081430 39082157 727 17925
FOXA1 MCF7GSE15244 39087670 39088328 658 11720
FOXA1 MCF7GSE15244 39095856 39096863 1007 3359
FOXA1 MCF7GSE15244 39098066 39099269 1203 1051
Fos K562GSE19551 39081149 39081885 736 18202
FoxA1 MCF7MACSdata 39096496 39096813 317 3064
P300 T30-glioblastomaGSE21026 39081050 39082027 977 18180
PHF8 293TGSE20725 39099196 39100137 941 52
RARA MCF7GSE15244 39081466 39082157 691 17907
RARA MCF7GSE15244 39087670 39088363 693 11702
RARA MCF7GSE15244 39088726 39089273 547 10719
RARA MCF7GSE15244 39098031 39099058 1027 1174
RARG MCF7GSE15244 39081430 39082157 727 17925
RARG MCF7GSE15244 39087670 39088363 693 11702
RARG MCF7GSE15244 39088726 39089236 510 10738
TFAP2C MCF7GSE21234 39081173 39082150 977 18057
TFAP2C MCF7GSE21234 39091242 39091727 485 8234
hScc1 BcellGSE12603 39098621 39100574 1953 121
p130 shRbSenescentGSE19898 39099377 39099825 448 118
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 39125029 39126023 994 6781
CBP T30-glioblastomaGSE21026 39133077 39134273 1196 14930
FOXA1 MCF7GSE15244 39125410 39125914 504 6917
FoxA1 MCF7MACSdata 39125399 39125664 265 6786
P300 T30-glioblastomaGSE21026 39124980 39126689 1709 7089
RARA MCF7GSE15244 39125142 39126022 880 6837
RARA MCF7GSE15244 39133194 39133960 766 14832
RARG MCF7GSE15244 39125410 39125914 504 6917
RARG MCF7GSE15244 39132014 39133924 1910 14224
SRF HelaGSE8489 39124591 39126296 1705 6698
SRF k562GSE8489 39124591 39125989 1398 6545
USF1 HepG2E 39125142 39125989 847 6820
p130 QuiescentGSE19898 39134708 39134849 141 16033
p130 SenescentGSE19898 39133372 39133544 172 14713
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 39113333 39114713 1380 0
FOXA1 MCF7GSE15244 39108244 39109309 1065 0
FOXA1 MCF7GSE15244 39113112 39114810 1698 0
FoxA1 MCF7MACSdata 39113589 39114052 463 0
H3K4me3 colorectalcancer 39099994 39100856 862 0
H3K4me3 colorectalcancer 39101553 39102135 582 0
H3ac HepG2E 39100395 39101082 687 0
H3ac HepG2E 39101553 39103879 2326 0
P300 T30-glioblastomaGSE21026 39113244 39114325 1081 0
RARG MCF7GSE15244 39108207 39108743 536 0
RARG MCF7GSE15244 39111752 39112421 669 0
RARG MCF7GSE15244 39113112 39114568 1456 0
RARG MCF7GSE15244 39115021 39115556 535 0
p130 SenescentGSE19898 39105123 39105337 214 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125a-3p hsa-mir-125a 19 16331254
hsa-miR-125a-5p hsa-mir-125a 19 16331254
hsa-miR-126 hsa-mir-126 9 20671229
hsa-miR-126* hsa-mir-126 9 20671229
hsa-miR-195 hsa-mir-195 17 16331254
hsa-miR-195* hsa-mir-195 17 16331254
hsa-miR-200a hsa-mir-200a 1 16331254
hsa-miR-200a* hsa-mir-200a 1 16331254
hsa-miR-224 hsa-mir-224 X 16331254
hsa-miR-7 hsa-mir-7-1 9 20978205
hsa-miR-7 hsa-mir-7-2 15 20978205
hsa-miR-7 hsa-mir-7-3 19 20978205
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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