Annotation Detail for ETV4

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Basic Information Top

Gene Symbol:	ETV4 ( E1A-F,E1AF,PEA3,PEAS3 )
Gene Full Name:	ets variant 4
Band:	17q21.31
Quick Links	Entrez ID:2118; OMIM: 600711; Uniprot ID:ETV4_HUMAN; ENSEMBL ID: ENSG00000175832; HGNC ID: 3493
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

TF binding site

Post Translation Modification

PTM Sites from Uniprot:2 results
Experimental PTM Sites from dbPTM:0 results
Predicted PTM Sites by profile HMM from dbPTM:12 results

Location(AA)	Modification
140	Phosphoserine.
149	Phosphoserine.

Location(AA)	Modification	Resource
22	Phosphoserine(CDC2)	HMM predict
73	Phosphoserine(ATM)	HMM predict
130	Phosphotyrosine(Jak)	HMM predict
130	Phosphotyrosine(INSR)	HMM predict
130	Phosphotyrosine(Syk)	HMM predict
169	Phosphoserine(ATM)	HMM predict
169	Phosphoserine(IKK)	HMM predict
214	O-linked	HMM predict
286	Phosphoserine(ATM)	HMM predict
289	O-linked	HMM predict
299	Phosphotyrosine(Jak)	HMM predict
449	Phosphoserine(CK2)	HMM predict

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

RefSeq ID: NM_001986
Location:chr17 38960740-38978772
strand:-

Upstream the gene:7 results
Downstream the gene:0 results
Inside the gene:12 results

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	38979250	38979687	437	696
H3ac	HepG2	E	38979991	38980750	759	1598
H3ac	HepG2	E	38989042	38989718	676	10608
H3ac	HepG2	E	38991998	38992855	857	13654
H3ac	HepG2	E	38993109	38993566	457	14565
Myc	K562	GSE19551	38989064	38989687	623	10603
p130	Senescent	GSE19898	38978527	38979131	604	57

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
Fos	K562	GSE19551	38969100	38969460	360	0
H3ac	HepG2	E	38962258	38963465	1207	0
H3ac	HepG2	E	38974324	38978512	4188	0
Myc	K562	GSE19551	38967862	38968151	289	0
TAF	k562	GSE8489	38977427	38978026	599	0
TFAP2C	MCF7	GSE21234	38972275	38972719	444	0
TFAP2C	MCF7	GSE21234	38977092	38977907	815	0
USF2	HepG2	E	38964629	38964890	261	0
USF2	HepG2	E	38977079	38978482	1403	0
hScc1	Bcell	GSE12603	38976937	38977144	207	0
p130	Senescent	GSE19898	38963291	38963984	693	0
p130	shRbQuiescent	GSE19898	38977577	38977987	410	0

Validated miRNA targets

miR Walk:2 results
Tarbase V5.0:0 results

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-125a-3p	hsa-mir-125a	19	19881956
hsa-miR-125a-5p	hsa-mir-125a	19	19881956

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
11207	EST		chr17	38954944	38977357	54	mRNA	ETV4	chr17	38960740	38978773	Sense/Antisense (SA) pairs

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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