AutismKB 2.0

Annotation Detail for ALDH1A1


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Basic Information Top
Gene Symbol:ALDH1A1 ( ALDC,ALDH-E1,ALDH1,ALDH11,MGC2318,PUMB1,RALDH1 )
Gene Full Name: aldehyde dehydrogenase 1 family, member A1
Band: 9q21.13
Quick LinksEntrez ID:216; OMIM: 100640; Uniprot ID:AL1A1_HUMAN; ENSEMBL ID: ENSG00000165092; HGNC ID: 402
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine.
91N6-acetyllysine.
128N6-acetyllysine.
252N6-acetyllysine.
353N6-acetyllysine.
367N6-acetyllysine.
410N6-acetyllysine.
419N6-acetyllysine.
435N6-acetyllysine.
495N6-acetyllysine.
Location(AA) Modifications Resource
2N-acetylserine.Swiss-Prot 53.0
Location(AA) Modification Resource
79Phosphothreonine(PKC)HMM predict
115Phosphotyrosine(INSR)HMM predict
119Phosphotyrosine(Syk)HMM predict
198Phosphothreonine(MAPK)HMM predict
267Phosphothreonine(PKA)HMM predict
316Phosphotyrosine(Syk)HMM predict
316Phosphotyrosine(SRC)HMM predict
316Phosphotyrosine(EGFR)HMM predict
323Phosphoserine(PKG)HMM predict
337Phosphothreonine(MAPK)HMM predict
351Phosphotyrosine(Syk)HMM predict
389N-linkedHMM predict
422N-linkedHMM predict
423N-linkedHMM predict
486Phosphotyrosine(INSR)HMM predict
486Phosphotyrosine(Syk)HMM predict
493Phosphothreonine(PKC)HMM predict
497Phosphoserine(PKG)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000689
  • Location:chr9 74705407-74757788
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 74764427 74764458 31 6654
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 74698363 74698396 33 7028
Oct1 H2O2-HelaGSE14283 74697690 74697786 96 7670
Oct1 H2O2-HelaGSE14283 74702331 74702360 29 3062
Oct1 HelaGSE14283 74697678 74697790 112 7674
Oct1 HelaGSE14283 74702330 74702365 35 3060
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 74757291 74757372 81 0
H3ac HepG2E 74752957 74754141 1184 0
Nanog hESGSE18292 74723359 74723672 313 0
Oct1 HelaGSE14283 74707144 74707205 61 0
Oct1 HelaGSE14283 74707663 74707755 92 0
Oct1 HelaGSE14283 74748509 74748573 64 0
VDR GM10861-stimGSE22484 74740907 74742931 2024 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 21292542
hsa-let-7a hsa-let-7a-2 11 21292542
hsa-let-7a hsa-let-7a-3 22 21292542
hsa-let-7a hsa-let-7a-1 9 21045151
hsa-let-7a hsa-let-7a-2 11 21045151
hsa-let-7a hsa-let-7a-3 22 21045151
hsa-let-7a* hsa-let-7a-1 9 21292542
hsa-let-7a* hsa-let-7a-3 22 21292542
hsa-let-7a* hsa-let-7a-1 9 21045151
hsa-let-7a* hsa-let-7a-3 22 21045151
hsa-let-7b hsa-let-7b 22 21292542
hsa-let-7b hsa-let-7b 22 21045151
hsa-let-7b* hsa-let-7b 22 21292542
hsa-let-7b* hsa-let-7b 22 21045151
hsa-let-7c hsa-let-7c 21 21292542
hsa-let-7c hsa-let-7c 21 21045151
hsa-let-7c* hsa-let-7c 21 21292542
hsa-let-7c* hsa-let-7c 21 21045151
hsa-let-7d hsa-let-7d 9 21292542
hsa-let-7d hsa-let-7d 9 21045151
hsa-let-7d* hsa-let-7d 9 21292542
hsa-let-7d* hsa-let-7d 9 21045151
hsa-let-7e hsa-let-7e 19 21292542
hsa-let-7e hsa-let-7e 19 21045151
hsa-let-7e* hsa-let-7e 19 21292542
hsa-let-7e* hsa-let-7e 19 21045151
hsa-let-7f hsa-let-7f-1 9 21292542
hsa-let-7f hsa-let-7f-2 X 21292542
hsa-let-7f hsa-let-7f-1 9 21045151
hsa-let-7f hsa-let-7f-2 X 21045151
hsa-let-7f-1* hsa-let-7f-1 9 21292542
hsa-let-7f-1* hsa-let-7f-1 9 21045151
hsa-let-7f-2* hsa-let-7f-2 X 21292542
hsa-let-7f-2* hsa-let-7f-2 X 21045151
hsa-let-7g hsa-let-7g 3 21292542
hsa-let-7g hsa-let-7g 3 21045151
hsa-let-7g* hsa-let-7g 3 21292542
hsa-let-7g* hsa-let-7g 3 21045151
hsa-let-7i hsa-let-7i 12 21292542
hsa-let-7i hsa-let-7i 12 21045151
hsa-let-7i* hsa-let-7i 12 21292542
hsa-let-7i* hsa-let-7i 12 21045151
hsa-miR-200b hsa-mir-200b 1 21363915
hsa-miR-200b* hsa-mir-200b 1 21363915
hsa-miR-200c hsa-mir-200c 12 21363915
hsa-miR-200c hsa-mir-200c 12 21294122
hsa-miR-200c hsa-mir-200c 12 21207483
hsa-miR-200c* hsa-mir-200c 12 21363915
hsa-miR-200c* hsa-mir-200c 12 21294122
hsa-miR-200c* hsa-mir-200c 12 21207483
hsa-miR-205 hsa-mir-205 1 21363915
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018