AutismKB 2.0

Annotation Detail for ACSL4


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Basic Information Top
Gene Symbol:ACSL4 ( ACS4,FACL4,LACS4,MRX63,MRX68 )
Gene Full Name: acyl-CoA synthetase long-chain family member 4
Band: Xq23
Quick LinksEntrez ID:2182; OMIM: 300157; Uniprot ID:ACSL4_HUMAN; ENSEMBL ID: ENSG00000068366; HGNC ID: 3571
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
89N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
51Phosphothreonine(PKC)HMM predict
57Phosphoserine(CDC2)HMM predict
57PhosphoserineHMM predict
67Phosphoserine(PKA)HMM predict
194N-linkedHMM predict
394Phosphotyrosine(EGFR)HMM predict
441Phosphoserine(ATM)HMM predict
447Phosphoserine(ATM)HMM predict
541SulfotyrosineHMM predict
542Phosphoserine(CK1)HMM predict
582Phosphotyrosine(Jak)HMM predict
704IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004458
  • Location:chrX 108771221-108863274
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 108869747 108870304 557 6751
FoxA1 MCF7MACSdata 108869895 108870225 330 6786
H3ac HepG2E 108863658 108864122 464 616
Pol2 GM12878GSE19551 108862876 108863732 856 30
TFAP2C MCF7GSE21234 108869940 108870222 282 6807
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 108765213 108765355 142 5938
CTCF CD4SISSRdata 108765213 108765355 142 5938
CTCF G2GSE9613 108765022 108765448 426 5987
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 108843990 108844876 886 0
CTCF CD4GSE12889 108842973 108843310 337 0
CTCF CD4SISSRdata 108842973 108843310 337 0
CTCF JurkatGSE12889 108843002 108843249 247 0
CTCF G2GSE9613 108842997 108843546 549 0
CTCF G2GSE9613 108862745 108863431 686 0
FOXA1 MCF7GSE15244 108809612 108809776 164 0
FoxA1 MCF7MACSdata 108809732 108809999 267 0
H3K4me3 colorectalcancer 108862450 108862709 259 0
H3ac HepG2E 108860169 108860855 686 0
H3ac HepG2E 108861730 108862806 1076 0
Myc K562GSE19551 108842862 108843254 392 0
NRSF mAbJurkat 108841692 108841959 267 0
Oct1 H2O2-HelaGSE14283 108841124 108841152 28 0
P300 T30-glioblastomaGSE21026 108843954 108844985 1031 0
TAFII hESGSE17917 108843002 108843209 207 0
hScc1 BcellGSE12603 108842997 108843176 179 0
hScc1 CdLSGSE12603 108842997 108843320 323 0
hScc1 G2GSE9613 108842997 108843642 645 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018