Annotation Detail for FAT1

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Basic Information Top

Gene Symbol:	FAT1 ( CDHF7,CDHR8,FAT,ME5,hFat1 )
Gene Full Name:	FAT tumor suppressor homolog 1 (Drosophila)
Band:	4q35.2
Quick Links	Entrez ID:2195; OMIM: 600976; Uniprot ID:FAT1_HUMAN; ENSEMBL ID: ENSG00000083857; HGNC ID: 3595
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modification
40	N-linked (GlcNAc...) (Potential).
152	Phosphothreonine.
333	N-linked (GlcNAc...) (Potential).
464	Phosphothreonine.
468	Phosphotyrosine.
660	N-linked (GlcNAc...) (Potential).
740	N-linked (GlcNAc...) (Potential).
791	N-linked (GlcNAc...) (Potential).
998	N-linked (GlcNAc...) (Potential).
1426	N-linked (GlcNAc...) (Potential).
1551	N-linked (GlcNAc...) (Potential).
1748	N-linked (GlcNAc...) (Potential).
1864	N-linked (GlcNAc...) (Potential).
1902	N-linked (GlcNAc...) (Potential).
1940	N-linked (GlcNAc...) (Potential).
1991	N-linked (GlcNAc...) (Potential).
2325	N-linked (GlcNAc...) (Potential).
2464	N-linked (GlcNAc...) (Potential).
2601	Phosphotyrosine.
2608	Phosphoserine.
2613	Phosphothreonine.
3324	N-linked (GlcNAc...) (Potential).
3415	N-linked (GlcNAc...).
3422	N-linked (GlcNAc...).
3444	N-linked (GlcNAc...) (Potential).
3613	N-linked (GlcNAc...) (Potential).
3640	N-linked (GlcNAc...) (Potential).
3716	N-linked (GlcNAc...).
4152	N-linked (GlcNAc...) (Potential).
4214	Nuclear localization signal (Potential).
4272	Phosphoserine.
4382	PTB-like motif (By similarity).

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	187882667	187883183	516	945
CTCF	G2	GSE9613	187883861	187885173	1312	2537
FoxA1	MCF7	MACSdata	187894113	187894269	156	12211
H3K4me2	HCT116	GSE10453	187883046	187883464	418	1275
H3K4me3	colorectal	cancer	187883146	187884317	1171	1751
H3ac	HepG2	E	187882985	187884755	1770	1890
P300	T30-glioblastoma	GSE21026	187893749	187894700	951	12244
PHF8	HeLa	GSE20725	187883704	187885571	1867	2657
hScc1	Bcell	GSE12603	187883797	187885318	1521	2577
hScc1	G2	GSE9613	187883908	187885318	1410	2633

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
CTCF	G2	GSE9613	187732349	187732543	194	13486
Rb	Quiescent	GSE19898	187738931	187739179	248	6877
hScc1	Bcell	GSE12603	187745608	187745996	388	130

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CBP	Jurkat	GSE17954	187748860	187752536	3676
CBP	Jurkat	GSE17954	187754416	187758027	3611
CTCF	G2	GSE9613	187756984	187757259	275
CTCF	G2	GSE9613	187789053	187789343	290
CTCF	G2	GSE9613	187817656	187817991	335
CTCF	G2	GSE9613	187827306	187827547	241
CTCF	G2	GSE9613	187840978	187841434	456
CTCF	G2	GSE9613	187856260	187856488	228
CTCF	G2	GSE9613	187860042	187860259	217
CTCF	G2	GSE9613	187881388	187882105	717
FOXA1	MCF7	GSE15244	187812032	187812737	705
FOXA1	eGFP	GSE10845	187812032	187812737	705
FoxA1	MCF7	MACSdata	187846833	187846994	161
H3ac	HepG2	E	187842328	187842791	463
H3ac	HepG2	E	187858123	187858519	396
H3ac	HepG2	E	187859129	187859796	667
H3ac	HepG2	E	187879237	187879956	719
H3ac	HepG2	E	187880565	187881388	823
NRSF	mAb	Jurkat	187753902	187755637	1735
P300	T0-glioblastoma	GSE21026	187834562	187835329	767
P300	T30-glioblastoma	GSE21026	187801947	187802726	779
P300	T30-glioblastoma	GSE21026	187834560	187835452	892
P300	T30-glioblastoma	GSE21026	187843691	187844685	994
PAX3-FKHR	Rh4	GSE19063	187764323	187765383	1060
RARA	MCF7	GSE15244	187812032	187812737	705
USF1	HepG2	E	187801472	187803421	1949
hScc1	Bcell	GSE12603	187773601	187773836	235
p130	shRbQuiescent	GSE19898	187779173	187779619	446
p130	shRbQuiescent	GSE19898	187827252	187827711	459
p63	keratinocytes	GSE17611	187857199	187858639	1440
p63	keratinocytes	GSE17611	187875427	187876413	986

Validated miRNA targets

Cis-Nats regulation

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018