AutismKB 2.0

Annotation Detail for FAT2


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Basic Information Top
Gene Symbol:FAT2 ( CDHF8,CDHR9,HFAT2,MEGF1 )
Gene Full Name: FAT tumor suppressor homolog 2 (Drosophila)
Band: 5q33.1
Quick LinksEntrez ID:2196; OMIM: 604269; Uniprot ID:FAT2_HUMAN; ENSEMBL ID: ENSG00000086570; HGNC ID: 3596
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
39N-linked (GlcNAc...) (Potential).
210N-linked (GlcNAc...) (Potential).
280N-linked (GlcNAc...) (Potential).
330N-linked (GlcNAc...) (Potential).
459N-linked (GlcNAc...) (Potential).
568N-linked (GlcNAc...) (Potential).
627N-linked (GlcNAc...) (Potential).
655N-linked (GlcNAc...) (Potential).
789N-linked (GlcNAc...) (Potential).
996N-linked (GlcNAc...) (Potential).
1175N-linked (GlcNAc...) (Potential).
1383N-linked (GlcNAc...) (Potential).
1417N-linked (GlcNAc...) (Potential).
1904N-linked (GlcNAc...) (Potential).
1998N-linked (GlcNAc...) (Potential).
2007N-linked (GlcNAc...) (Potential).
2165N-linked (GlcNAc...) (Potential).
2183N-linked (GlcNAc...) (Potential).
2205Phosphotyrosine.
2233Phosphotyrosine.
2325N-linked (GlcNAc...) (Potential).
2368N-linked (GlcNAc...) (Potential).
2387N-linked (GlcNAc...) (Potential).
2430N-linked (GlcNAc...) (Potential).
2470N-linked (GlcNAc...) (Potential).
2547N-linked (GlcNAc...) (Potential).
2597N-linked (GlcNAc...) (Potential).
2654N-linked (GlcNAc...) (Potential).
3125N-linked (GlcNAc...) (Potential).
3276N-linked (GlcNAc...) (Potential).
3310N-linked (GlcNAc...) (Potential).
3430N-linked (GlcNAc...) (Potential).
3471N-linked (GlcNAc...) (Potential).
3601N-linked (GlcNAc...) (Potential).
3772N-linked (GlcNAc...) (Potential).
3813N-linked (GlcNAc...) (Potential).
3840N-linked (GlcNAc...) (Potential).
3873N-linked (GlcNAc...) (Potential).
3904N-linked (GlcNAc...).
3989N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
39N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
210N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
280N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
330N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
459N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
568N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
627N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
655N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
789N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
996N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1175N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1303N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1383N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1417N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1904N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1998N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2007N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2165N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2183N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2325N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2368N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2387N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2430N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2470N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2547N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2597N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2654N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3125N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3276N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3310N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3430N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3471N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3601N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3772N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3813N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3840N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3873N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
3904N-linked (GlcNAc...).Swiss-Prot 53.0
3989N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
39N-linkedHMM predict
45N-linkedHMM predict
87Phosphotyrosine(INSR)HMM predict
210N-linkedHMM predict
231Phosphoserine(PKG)HMM predict
262Phosphothreonine(MAPK)HMM predict
280N-linkedHMM predict
288Phosphoserine(CK1)HMM predict
313Phosphoserine(CK1)HMM predict
387Phosphothreonine(PKA)HMM predict
459N-linkedHMM predict
492Phosphotyrosine(INSR)HMM predict
492Phosphotyrosine(Syk)HMM predict
522Phosphotyrosine(INSR)HMM predict
568N-linkedHMM predict
627N-linkedHMM predict
648Phosphotyrosine(INSR)HMM predict
655N-linkedHMM predict
694Phosphoserine(CK2)HMM predict
694Phosphoserine(CK2)HMM predict
695Phosphoserine(CK2)HMM predict
695PhosphoserineHMM predict
732Phosphothreonine(MAPK)HMM predict
789N-linkedHMM predict
849Phosphoserine(CK1)HMM predict
849PhosphoserineHMM predict
861Phosphoserine(CDC2)HMM predict
885Phosphoserine(CK1)HMM predict
1045Phosphoserine(CDC2)HMM predict
1047Phosphoserine(CK1)HMM predict
1061Phosphoserine(CK1)HMM predict
1175N-linkedHMM predict
1180N-linkedHMM predict
1256Phosphoserine(CDC2)HMM predict
1256Phosphoserine(MAPK)HMM predict
1256Phosphoserine(IKK)HMM predict
1259O-linkedHMM predict
1259Phosphoserine(CDC2)HMM predict
1259Phosphoserine(MAPK)HMM predict
1282Phosphoserine(IKK)HMM predict
1287Phosphotyrosine(EGFR)HMM predict
1301O-linkedHMM predict
1303N-linkedHMM predict
1305O-linkedHMM predict
1343O-linkedHMM predict
1410Phosphothreonine(PKC)HMM predict
1414Phosphoserine(PKG)HMM predict
1414PhosphoserineHMM predict
1417N-linkedHMM predict
1488Phosphoserine(ATM)HMM predict
1508Phosphothreonine(PKC)HMM predict
1519Phosphoserine(ATM)HMM predict
1665Phosphotyrosine(INSR)HMM predict
1692Phosphotyrosine(SRC)HMM predict
1830Phosphotyrosine(INSR)HMM predict
1830Phosphotyrosine(SRC)HMM predict
1830Phosphotyrosine(Syk)HMM predict
1866N-linkedHMM predict
1877Phosphotyrosine(SRC)HMM predict
1877Phosphotyrosine(Syk)HMM predict
1901Phosphoserine(CK1)HMM predict
1940Phosphothreonine(PKC)HMM predict
1998N-linkedHMM predict
2007N-linkedHMM predict
2035Phosphothreonine(CK2)HMM predict
2045N-linkedHMM predict
2047Phosphothreonine(CDC2)HMM predict
2155Phosphoserine(CK1)HMM predict
2162Phosphothreonine(PKC)HMM predict
2165N-linkedHMM predict
2168N-linkedHMM predict
2175Phosphotyrosine(Jak)HMM predict
2176Phosphotyrosine(Jak)HMM predict
2176Phosphotyrosine(Jak)HMM predict
2183N-linkedHMM predict
2197Phosphoserine(CDC2)HMM predict
2197Phosphoserine(CDK)HMM predict
2339SulfotyrosineHMM predict
2368N-linkedHMM predict
2373N-linkedHMM predict
2387N-linkedHMM predict
2430N-linkedHMM predict
2470N-linkedHMM predict
2473N-linkedHMM predict
2475N-linkedHMM predict
2477Phosphotyrosine(Jak)HMM predict
2513Phosphotyrosine(INSR)HMM predict
2547N-linkedHMM predict
2548Phosphoserine(CK1)HMM predict
2548PhosphoserineHMM predict
2596O-linkedHMM predict
2597N-linkedHMM predict
2602Phosphoserine(CDC2)HMM predict
2654N-linkedHMM predict
2731Phosphothreonine(MAPK)HMM predict
2731Phosphothreonine(CDK)HMM predict
2802Phosphotyrosine(Syk)HMM predict
2958Phosphoserine(ATM)HMM predict
2971Phosphothreonine(PKC)HMM predict
3125N-linkedHMM predict
3126O-linkedHMM predict
3200O-linkedHMM predict
3203O-linkedHMM predict
3214Phosphotyrosine(Syk)HMM predict
3253Phosphotyrosine(Syk)HMM predict
3298Phosphoserine(IKK)HMM predict
3300O-linkedHMM predict
3300Phosphoserine(CK1)HMM predict
3302Phosphoserine(CK1)HMM predict
3310N-linkedHMM predict
3315N-linkedHMM predict
3399Phosphothreonine(PKA)HMM predict
3430N-linkedHMM predict
3451Phosphoserine(ATM)HMM predict
3455Phosphoserine(IKK)HMM predict
3471N-linkedHMM predict
3522O-linkedHMM predict
3579Phosphoserine(CAMK2)HMM predict
3601N-linkedHMM predict
3611O-linkedHMM predict
3757Phosphoserine(PKG)HMM predict
3772N-linkedHMM predict
3813N-linkedHMM predict
3840N-linkedHMM predict
3952Phosphoserine(ATM)HMM predict
3989N-linkedHMM predict
4004Phosphoserine(CDC2)HMM predict
4016Phosphotyrosine(Abl)HMM predict
4109Phosphoserine(IKK)HMM predict
4168Phosphoserine(IKK)HMM predict
4211O-linkedHMM predict
4258Phosphoserine(CDC2)HMM predict
4258Phosphoserine(CDK)HMM predict
4258PhosphoserineHMM predict
4279Phosphoserine(ATM)HMM predict
4303Phosphoserine(PKG)HMM predict
4309Phosphotyrosine(Jak)HMM predict
4341Phosphotyrosine(EGFR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001447
  • Location:chr5 150863846-150928697
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 150941880 150942136 256 13311
CTCF G2GSE9613 150943789 150944114 325 15254
ER E2-MCF7GSE14664 150929051 150929086 35 371
Oct1 H2O2-HelaGSE14283 150932039 150932067 28 3356
Oct1 H2O2-HelaGSE14283 150948394 150948421 27 19710
Oct1 HelaGSE14283 150929056 150929090 34 376
Oct1 HelaGSE14283 150948386 150948422 36 19707
Stat6 IL-4-hr4GSE17850 150931264 150931623 359 2746
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 150860505 150860814 309 3187
CTCF CD4SISSRdata 150860505 150860814 309 3187
CTCF HelaGSE12889 150860539 150860817 278 3169
CTCF G2GSE9613 150860521 150860912 391 3130
GABP k562GSE8489 150863255 150863453 198 493
TAF HelaGSE8489 150863255 150863453 198 493
hScc1 BcellGSE12603 150860521 150860876 355 3148
hScc1 CdLSGSE12603 150860521 150861023 502 3075
hScc1 G2GSE9613 150860521 150861023 502 3075
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 150863784 150864097 313 0
CTCF G2GSE9613 150864662 150865574 912 0
CTCF G2GSE9613 150869649 150870147 498 0
CTCF G2GSE9613 150872034 150872289 255 0
CTCF G2GSE9613 150877016 150877370 354 0
CTCF G2GSE9613 150879746 150880024 278 0
CTCF G2GSE9613 150881104 150881962 858 0
CTCF G2GSE9613 150882413 150882744 331 0
CTCF G2GSE9613 150883316 150883485 169 0
CTCF G2GSE9613 150885433 150885720 287 0
CTCF G2GSE9613 150890820 150891137 317 0
CTCF G2GSE9613 150895998 150896226 228 0
CTCF G2GSE9613 150915925 150916187 262 0
CTCF G2GSE9613 150925529 150925911 382 0
Oct1 H2O2-HelaGSE14283 150927917 150927958 41 0
Oct1 HelaGSE14283 150895974 150896003 29 0
Oct1 HelaGSE14283 150896850 150896881 31 0
Oct1 HelaGSE14283 150909104 150909137 33 0
Oct1 HelaGSE14283 150927917 150927955 38 0
Oct4 hESGSE17917 150894178 150894421 243 0
RNAII Tamoxifen-MCF7GSE14664 150927917 150927966 49 0
hScc1 BcellGSE12603 150883316 150883620 304 0
hScc1 CdLSGSE12603 150883316 150883557 241 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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