AutismKB 2.0

Annotation Detail for MARCH8


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Basic Information Top
Gene Symbol:MARCH8 ( MARCH-VIII,MIR,RNF178,c-MIR )
Gene Full Name: membrane-associated ring finger (C3HC4) 8
Band: 10q11.21
Quick LinksEntrez ID:220972; OMIM: 613335; Uniprot ID:MARH8_HUMAN; ENSEMBL ID: ENSG00000165406; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
13Phosphoserine(ATM)HMM predict
48N-linkedHMM predict
54Phosphoserine(CDC2)HMM predict
57O-linkedHMM predict
57Phosphoserine(IKK)HMM predict
57O-linkedHMM predict
59O-linkedHMM predict
66O-linkedHMM predict
68O-linkedHMM predict
70O-linkedHMM predict
71O-linkedHMM predict
73Phosphothreonine(MAPK)HMM predict
216Phosphotyrosine(Jak)HMM predict
274N-linkedHMM predict
277S-farnesylHMM predict
278S-farnesylHMM predict
278CysteineHMM predict
284Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001002265
  • Location:chr10 45272822-45410359
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 45409918 45410851 933 25
Fos K562GSE19551 45410039 45410713 674 17
USF1 HepG2E 45410461 45410893 432 318
USF1 HepG2E 45411222 45412154 932 1329
USF1 HepG2E 45412565 45412887 322 2367
USF1 HepG2E 45414024 45414320 296 3813
USF1 HepG2E 45414689 45415192 503 4581
USF2 HepG2E 45410500 45410893 393 337
USF2 HepG2E 45411222 45412110 888 1307
p130 QuiescentGSE19898 45410200 45410623 423 52
p130 SenescentGSE19898 45410188 45410557 369 13
p130 shRbQuiescentGSE19898 45410213 45410632 419 63
p130 shRbSenescentGSE19898 45410212 45410548 336 21
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER Fulvestrant-MCF7GSE14664 45409004 45409043 39 0
GABP k562GSE8489 45372887 45373480 593 0
H3K4me3 colorectalcancer 45408536 45409939 1403 0
H3ac HepG2E 45408536 45409708 1172 0
HIF1 HypoHepG2 45410011 45410570 559 0
KLF4 hESGSE17917 45381144 45381379 235 0
Nanog ESGSE20650 45390427 45390912 485 0
Oct1 HelaGSE14283 45409003 45409047 44 0
Oct4 hESGSE17917 45410153 45410507 354 0
P300 T0-glioblastomaGSE21026 45410073 45410523 450 0
P300 T30-glioblastomaGSE21026 45410103 45410598 495 0
PHF8 293TGSE20725 45409277 45410867 1590 0
PHF8 HeLaGSE20725 45409483 45410821 1338 0
PHF8 Hs68minusFBSGSE20725 45409679 45410809 1130 0
RNAII Tamoxifen-MCF7GSE14664 45409001 45409043 42 0
USF1 HepG2E 45408536 45409892 1356 0
p63 keratinocytesGSE17611 45368841 45369572 731 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018