AutismKB 2.0

Annotation Detail for OPN5


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Basic Information Top
Gene Symbol:OPN5 ( GPR136,PGR12,TMEM13 )
Gene Full Name: opsin 5
Band: 6p12.3
Quick LinksEntrez ID:221391; OMIM: 609042; Uniprot ID:OPN5_HUMAN; ENSEMBL ID: ENSG00000124818; HGNC ID: 19992
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
4N-linked (GlcNAc...) (Potential).
296N6-(retinylidene)lysine.
Location(AA) Modifications Resource
4N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
315S-palmitoyl cysteine (Potential).Swiss-Prot 53.0
316S-palmitoyl cysteine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
106S-palmitoylHMM predict
150Phosphotyrosine(INSR)HMM predict
174Phosphotyrosine(INSR)HMM predict
229Phosphoserine(PKG)HMM predict
230Phosphoserine(CK1)HMM predict
282Phosphoserine(IKK)HMM predict
339Phosphothreonine(PKC)HMM predict
343Phosphoserine(PKG)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_181744
  • Location:chr6 47857756-47902072
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 47856523 47856738 215 1126
CTCF CD4SISSRdata 47856523 47856738 215 1126
CTCF G2GSE9613 47856242 47856855 613 1208
ER E2-MCF7GSE14664 47844305 47844349 44 13430
Myc K562GSE19551 47856472 47856687 215 1177
Oct1 H2O2-HelaGSE14283 47844400 47844428 28 13343
hScc1 BcellGSE12603 47856320 47856789 469 1202
hScc1 CdLSGSE12603 47856208 47856888 680 1209
hScc1 G2GSE9613 47856285 47856828 543 1200
No data
No data
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018