AutismKB 2.0

Annotation Detail for KDM1B


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Basic Information Top
Gene Symbol:KDM1B ( AOF1,C6orf193,DKFZp686I0412,FLJ33898,FLJ34109,FLJ43328,LSD2,bA204B7.3,dJ298J15.2 )
Gene Full Name: lysine (K)-specific demethylase 1B
Band: 6p22.3
Quick LinksEntrez ID:221656; OMIM: 613081; Uniprot ID:KDM1B_HUMAN; ENSEMBL ID: ENSG00000165097; HGNC ID: 21577
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
17Phosphoserine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_153042
  • Location:chr6 18263597-18332062
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 18263482 18263763 281 0
CTCF G2GSE9613 18323158 18323473 315 0
KLF4 hESGSE17917 18331538 18331694 156 0
NFkBII GM12878GSE19485 18263825 18265078 1253 0
NFkBII GM18526GSE19485 18262554 18265258 2704 0
Oct1 H2O2-HelaGSE14283 18319240 18319270 30 0
Oct1 H2O2-HelaGSE14283 18327894 18327923 29 0
Oct1 HelaGSE14283 18313138 18313173 35 0
Oct1 HelaGSE14283 18319240 18319268 28 0
Oct1 HelaGSE14283 18327894 18327971 77 0
Oct4 hESGSE21916 18294298 18294601 303 0
VDR GM10861-stimGSE22484 18262349 18264978 2629 0
p130 shRbQuiescentGSE19898 18263985 18264516 531 0
Validated miRNA targets Top
No data
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
678 Unknown MicroArray miR-373 AOF1 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000165097 n_a n_a n_a lymphocyte "benign tumour, malignant tumour, carcinoma, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018