AutismKB 2.0

Annotation Detail for SCUBE3


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Basic Information Top
Gene Symbol:SCUBE3 ( CEGF3,DKFZp686B09105,DKFZp686B1223,DKFZp686D20108,FLJ34743 )
Gene Full Name: signal peptide, CUB domain, EGF-like 3
Band: 6p21.3
Quick LinksEntrez ID:222663; OMIM: NA; Uniprot ID:SCUB3_HUMAN; ENSEMBL ID: ENSG00000146197; HGNC ID: 13655
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
417N-linked (GlcNAc...) (Potential).
464N-linked (GlcNAc...) (Potential).
685N-linked (GlcNAc...) (Potential).
756N-linked (GlcNAc...) (Potential).
785N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
417N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
464N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
685N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
756N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
785N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
175Phosphothreonine(CDC2)HMM predict
343S-palmitoylHMM predict
417N-linkedHMM predict
451O-linkedHMM predict
464N-linkedHMM predict
467N-linkedHMM predict
469N-linkedHMM predict
541Phosphothreonine(MAPK)HMM predict
541Phosphothreonine(CDC2)HMM predict
541Phosphothreonine(PKA)HMM predict
541Phosphothreonine(CDK)HMM predict
551Phosphothreonine(PKA)HMM predict
685N-linkedHMM predict
688O-linkedHMM predict
706S-palmitoylHMM predict
726S-palmitoylHMM predict
731Phosphothreonine(PKC)HMM predict
756N-linkedHMM predict
785N-linkedHMM predict
814Phosphotyrosine(EGFR)HMM predict
820Phosphotyrosine(INSR)HMM predict
866N-linkedHMM predict
867PhosphoserineHMM predict
867Phosphoserine(IKK)HMM predict
867Phosphoserine(PKG)HMM predict
868Phosphoserine(CDC2)HMM predict
873O-linkedHMM predict
874O-linkedHMM predict
920Phosphotyrosine(Syk)HMM predict
920Phosphotyrosine(INSR)HMM predict
920SulfotyrosineHMM predict
934Phosphotyrosine(INSR)HMM predict
981LeucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_152753
  • Location:chr6 35290167-35326586
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35280849 35281113 264 9187
CTCF CD4SISSRdata 35280849 35281113 264 9187
CTCF JurkatGSE12889 35280891 35281132 241 9156
CTCF G2GSE9613 35279124 35279709 585 10751
CTCF G2GSE9613 35280154 35280297 143 9942
CTCF G2GSE9613 35280801 35281094 293 9220
CTCF G2GSE9613 35284274 35285193 919 5434
CTCF G2GSE9613 35289743 35290530 787 31
ER E2-MCF7GSE14664 35284905 35285001 96 5215
ER Fulvestrant-MCF7GSE14664 35284903 35285003 100 5215
H3K27me3 colorectalcancer 35283337 35285114 1777 5942
Myc hESGSE17917 35289187 35289479 292 835
hScc1 BcellGSE12603 35279279 35279643 364 10707
hScc1 BcellGSE12603 35280632 35281094 462 9305
hScc1 BcellGSE12603 35289880 35290397 517 29
hScc1 CdLSGSE12603 35280632 35281094 462 9305
hScc1 G2GSE9613 35280154 35281094 940 9544
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 35329944 35329973 29 3372
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 35316855 35317293 438 0
CTCF CD4SISSRdata 35316855 35317293 438 0
CTCF HelaGSE12889 35316783 35317246 463 0
CTCF JurkatGSE12889 35316910 35317267 357 0
CTCF G2GSE9613 35297681 35298238 557 0
CTCF G2GSE9613 35308770 35309243 473 0
CTCF G2GSE9613 35316847 35317771 924 0
CTCF G2GSE9613 35318800 35318933 133 0
CTCF G2GSE9613 35319393 35319762 369 0
H3K27me3 colorectalcancer 35291102 35292224 1122 0
Nanog hESGSE18292 35325163 35325398 235 0
Oct4 hESGSE17917 35292901 35293173 272 0
hScc1 BcellGSE12603 35316534 35317980 1446 0
hScc1 CdLSGSE12603 35316606 35317399 793 0
hScc1 G2GSE9613 35316606 35317740 1134 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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