AutismKB 2.0

Annotation Detail for FER


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Basic Information Top
Gene Symbol:FER ( TYK3 )
Gene Full Name: fer (fps/fes related) tyrosine kinase
Band: 5q21.3
Quick LinksEntrez ID:2241; OMIM: 176942; Uniprot ID:FER_HUMAN; ENSEMBL ID: ENSG00000151422; HGNC ID: 3655
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
402Phosphotyrosine.
410Phosphothreonine.
411Phosphoserine.
434Phosphoserine.
714Phosphotyrosine; by autocatalysis.
Location(AA) Modifications Resource
402Phosphotyrosine.Swiss-Prot 53.0
434Phosphoserine.Swiss-Prot 53.0
714Phosphotyrosine (by autocatalysis).Swiss-Prot 53.0
714PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
42Phosphotyrosine(Syk)HMM predict
66N-linkedHMM predict
164Phosphothreonine(PKC)HMM predict
171Phosphotyrosine(EGFR)HMM predict
199Phosphotyrosine(Syk)HMM predict
270Phosphothreonine(PKA)HMM predict
299N-linkedHMM predict
408Phosphoserine(IKK)HMM predict
410Phosphothreonine(PKC)HMM predict
437Phosphoserine(IKK)HMM predict
581Phosphothreonine(PKC)HMM predict
714Phosphotyrosine(Jak)HMM predict
822ThreonineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005246
  • Location:chr5 108111421-108551271
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 108091402 108091974 572 19734
PHF8 293TGSE20725 108091473 108092273 800 19549
PHF8 HeLaGSE20725 108091071 108092588 1517 19592
PHF8 Hs68plusFBSGSE20725 108090864 108092285 1421 19847
TAF HelaGSE8489 108092309 108093046 737 18744
hScc1 BcellGSE12603 108091402 108091757 355 19842
hScc1 CdLSGSE12603 108091402 108092039 637 19701
hScc1 G2GSE9613 108091402 108091974 572 19734
p130 QuiescentGSE19898 108091125 108092155 1030 19782
p130 shRbSenescentGSE19898 108091210 108092233 1023 19700
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 108554837 108555222 385 3758
Oct1 HelaGSE14283 108564874 108564914 40 13623
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 108165031 108165961 930 0
CTCF G2GSE9613 108111758 108113157 1399 0
ER E2-MCF7GSE14664 108132301 108132343 42 0
ER E2-MCF7GSE14664 108268848 108268885 37 0
ER E2-MCF7GSE14664 108468535 108468585 50 0
ER E2-MCF7GSE14664 108501690 108501729 39 0
ER Fulvestrant-MCF7GSE14664 108132298 108132343 45 0
ER Fulvestrant-MCF7GSE14664 108468538 108468585 47 0
Fos K562GSE19551 108111969 108112893 924 0
Fos K562GSE19551 108165353 108165838 485 0
H3K4me3 colorectalcancer 108111441 108111957 516 0
Jun K562GSE19551 108165364 108165754 390 0
KLF4 hESGSE17917 108112555 108112967 412 0
Myc K562GSE19551 108317585 108317928 343 0
Nanog ESGSE20650 108214638 108215134 496 0
Nanog ESGSE20650 108308581 108309108 527 0
Nanog hESGSE18292 108308591 108309066 475 0
Oct1 H2O2-HelaGSE14283 108118250 108118278 28 0
Oct1 H2O2-HelaGSE14283 108125930 108125961 31 0
Oct1 H2O2-HelaGSE14283 108132301 108132339 38 0
Oct1 H2O2-HelaGSE14283 108132496 108132524 28 0
Oct1 H2O2-HelaGSE14283 108139463 108139515 52 0
Oct1 H2O2-HelaGSE14283 108145612 108145647 35 0
Oct1 H2O2-HelaGSE14283 108168906 108168937 31 0
Oct1 H2O2-HelaGSE14283 108169094 108169122 28 0
Oct1 H2O2-HelaGSE14283 108194485 108194523 38 0
Oct1 H2O2-HelaGSE14283 108194995 108195032 37 0
Oct1 H2O2-HelaGSE14283 108208103 108208133 30 0
Oct1 H2O2-HelaGSE14283 108219836 108219869 33 0
Oct1 H2O2-HelaGSE14283 108228450 108228487 37 0
Oct1 H2O2-HelaGSE14283 108240160 108240199 39 0
Oct1 H2O2-HelaGSE14283 108241984 108242027 43 0
Oct1 H2O2-HelaGSE14283 108313319 108313346 27 0
Oct1 H2O2-HelaGSE14283 108319800 108319833 33 0
Oct1 H2O2-HelaGSE14283 108345228 108345259 31 0
Oct1 H2O2-HelaGSE14283 108395317 108395347 30 0
Oct1 H2O2-HelaGSE14283 108413549 108413585 36 0
Oct1 H2O2-HelaGSE14283 108472211 108472242 31 0
Oct1 H2O2-HelaGSE14283 108474593 108474632 39 0
Oct1 H2O2-HelaGSE14283 108508543 108508570 27 0
Oct1 HelaGSE14283 108125930 108125965 35 0
Oct1 HelaGSE14283 108126805 108126837 32 0
Oct1 HelaGSE14283 108132301 108132384 83 0
Oct1 HelaGSE14283 108132493 108132531 38 0
Oct1 HelaGSE14283 108145614 108145644 30 0
Oct1 HelaGSE14283 108151080 108151115 35 0
Oct1 HelaGSE14283 108168904 108168938 34 0
Oct1 HelaGSE14283 108169094 108169122 28 0
Oct1 HelaGSE14283 108194491 108194548 57 0
Oct1 HelaGSE14283 108194992 108195034 42 0
Oct1 HelaGSE14283 108219835 108219868 33 0
Oct1 HelaGSE14283 108228446 108228492 46 0
Oct1 HelaGSE14283 108240165 108240199 34 0
Oct1 HelaGSE14283 108241984 108242035 51 0
Oct1 HelaGSE14283 108268290 108268338 48 0
Oct1 HelaGSE14283 108268857 108268895 38 0
Oct1 HelaGSE14283 108275105 108275134 29 0
Oct1 HelaGSE14283 108312629 108312660 31 0
Oct1 HelaGSE14283 108313313 108313346 33 0
Oct1 HelaGSE14283 108319798 108319833 35 0
Oct1 HelaGSE14283 108370208 108370240 32 0
Oct1 HelaGSE14283 108395319 108395352 33 0
Oct1 HelaGSE14283 108397009 108397044 35 0
Oct1 HelaGSE14283 108413549 108413585 36 0
Oct1 HelaGSE14283 108468544 108468578 34 0
Oct1 HelaGSE14283 108472207 108472244 37 0
Oct1 HelaGSE14283 108475666 108475702 36 0
Oct1 HelaGSE14283 108508544 108508576 32 0
P300 T30-glioblastomaGSE21026 108164981 108166024 1043 0
PHF8 293TGSE20725 108111711 108112498 787 0
PHF8 HeLaGSE20725 108111314 108113502 2188 0
PHF8 Hs68minusFBSGSE20725 108111527 108113013 1486 0
RNAII Tamoxifen-MCF7GSE14664 108240156 108240198 42 0
Rb QuiescentGSE19898 108112004 108112122 118 0
Rb QuiescentGSE19898 108112523 108112657 134 0
Rb SenescentGSE19898 108112394 108113023 629 0
TAF HelaGSE8489 108111217 108111989 772 0
TAF k562GSE8489 108111217 108112029 812 0
USF1 HepG2E 108113025 108114421 1396 0
hScc1 BcellGSE12603 108111850 108112234 384 0
hScc1 G2GSE9613 108111826 108113130 1304 0
p130 QuiescentGSE19898 108112223 108112458 235 0
p130 SenescentGSE19898 108111969 108113167 1198 0
p130 shRbQuiescentGSE19898 108112059 108112442 383 0
p130 shRbQuiescentGSE19898 108112599 108112879 280 0
p130 shRbSenescentGSE19898 108111890 108113162 1272 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
21309 mRNA FER chr5 108111421 108551272 3479 EST chr5 108527066 108530545 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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