AutismKB 2.0

Annotation Detail for FGA


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Basic Information Top
Gene Symbol:FGA ( Fib2,MGC119422,MGC119423,MGC119425 )
Gene Full Name: fibrinogen alpha chain
Band: 4q31.3
Quick LinksEntrez ID:2243; OMIM: 134820; Uniprot ID:FIBA_HUMAN; ENSEMBL ID: ENSG00000171560; HGNC ID: 3661
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
22Phosphoserine.
277Phosphotyrosine.
364Phosphoserine.
412Phosphothreonine.
453N-linked (GlcNAc...); in variant Caracas-
524Phosphoserine.
546Phosphoserine.
549Phosphoserine.
609Phosphoserine.
686N-linked (GlcNAc...).
Location(AA) Modifications Resource
22Phosphoserine.Swiss-Prot 53.0
22PhosphoserinePhospho.ELM 6.0
322Isoglutamyl lysine isopeptide (Lys-Gln)(interchain with Q-41 in alpha-2-antiplasmin).Swiss-Prot 53.0
347Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-?).Swiss-Prot 53.0
385Isoglutamyl lysine isopeptide (Gln-Lys)(interchain with K-?).Swiss-Prot 53.0
453N-linked (GlcNAc...); in variant Caracas-2.Swiss-Prot 53.0
460Phosphoserine (PKA
527Isoglutamyl lysine isopeptide (Lys-Gln)(interchain with Q-?) (Potential).Swiss-Prot 53.0
558Isoglutamyl lysine isopeptide (Lys-Gln)(interchain with Q-?) (Potential).Swiss-Prot 53.0
575Isoglutamyl lysine isopeptide (Lys-Gln)(interchain with Q-?) (Potential).Swiss-Prot 53.0
576Phosphoserine (PKC
577Phosphoserine (PKC
578Phosphoserine (PKC
581Isoglutamyl lysine isopeptide (Lys-Gln)(interchain with Q-?) (Potential).Swiss-Prot 53.0
599Isoglutamyl lysine isopeptide (Lys-Gln)(interchain with Q-?) (Potential).Swiss-Prot 53.0
618Phosphoserine (PKC
686N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
16O-linkedHMM predict
22PhosphoserineHMM predict
62Phosphotyrosine(INSR)HMM predict
104Phosphoserine(CK1)HMM predict
104Phosphoserine(IKK)HMM predict
127Phosphotyrosine(Syk)HMM predict
183Phosphoserine(PKA)HMM predict
197Phosphotyrosine(INSR)HMM predict
197SulfotyrosineHMM predict
197Phosphotyrosine(Syk)HMM predict
281O-linkedHMM predict
285Phosphoserine(CDC2)HMM predict
288N-linkedHMM predict
291O-linkedHMM predict
294Phosphoserine(IKK)HMM predict
299O-linkedHMM predict
313O-linkedHMM predict
325O-linkedHMM predict
333Phosphoserine(IKK)HMM predict
338O-linkedHMM predict
343O-linkedHMM predict
351O-linkedHMM predict
351Phosphoserine(CDC2)HMM predict
351PhosphoserineHMM predict
356O-linkedHMM predict
375O-linkedHMM predict
377O-linkedHMM predict
378Phosphoserine(CK1)HMM predict
397Phosphoserine(CDC2)HMM predict
397Phosphoserine(IKK)HMM predict
421Phosphoserine(CDK)HMM predict
421Phosphoserine(CDC2)HMM predict
424Phosphothreonine(PKC)HMM predict
444Phosphothreonine(PKC)HMM predict
451O-linkedHMM predict
454O-linkedHMM predict
456O-linkedHMM predict
456Phosphothreonine(PKC)HMM predict
457O-linkedHMM predict
460Phosphoserine(PKA)HMM predict
460O-linkedHMM predict
462O-linkedHMM predict
489Phosphoserine(CK2)HMM predict
549Phosphoserine(CK2)HMM predict
549Phosphoserine(CK1)HMM predict
576Phosphoserine(PKA)HMM predict
578Phosphoserine(PKC)HMM predict
580O-linkedHMM predict
601Phosphotyrosine(Syk)HMM predict
609Phosphoserine(CK2)HMM predict
668Phosphoserine(CK1)HMM predict
686N-linkedHMM predict
777Phosphotyrosine(INSR)HMM predict
831N-linkedHMM predict
832N-linkedHMM predict
833Phosphoserine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021871
  • Location:chr4 155725878-155731346
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 155736475 155736633 158 5208
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 155731077 155731431 354 0
H3ac HepG2E 155725870 155729194 3324 0
H3ac HepG2E 155729462 155731393 1931 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-29a hsa-mir-29a 7 20570858
hsa-miR-29a* hsa-mir-29a 7 20570858
hsa-miR-29b hsa-mir-29b-1 7 20570858
hsa-miR-29b hsa-mir-29b-2 1 20570858
hsa-miR-29b-1* hsa-mir-29b-1 7 20570858
hsa-miR-29b-2* hsa-mir-29b-2 1 20570858
hsa-miR-29c hsa-mir-29c 1 20570858
hsa-miR-29c* hsa-mir-29c 1 20570858
hsa-miR-409-3p hsa-mir-409 14 20570858
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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