AutismKB 2.0

Annotation Detail for FGD1


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Basic Information Top
Gene Symbol:FGD1 ( AAS,FGDY,MRXS16,ZFYVE3 )
Gene Full Name: FYVE, RhoGEF and PH domain containing 1
Band: Xp11.22
Quick LinksEntrez ID:2245; OMIM: 300546; Uniprot ID:FGD1_HUMAN; ENSEMBL ID: ENSG00000102302; HGNC ID: 3663
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
48Phosphoserine.
179SH3-binding (Potential).
187SH3-binding (Potential).
205Phosphoserine.
704Phosphothreonine.
711Phosphothreonine.
715Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
13O-linkedHMM predict
48Phosphoserine(PKA)HMM predict
98Phosphoserine(ATM)HMM predict
141O-linkedHMM predict
143Phosphothreonine(CDK)HMM predict
143Phosphothreonine(MAPK)HMM predict
143O-linkedHMM predict
145Phosphoserine(ATM)HMM predict
145O-linkedHMM predict
149Phosphoserine(CDK)HMM predict
149Phosphoserine(CDK)HMM predict
149Phosphoserine(CDC2)HMM predict
185O-linkedHMM predict
205O-linkedHMM predict
207O-linkedHMM predict
208O-linkedHMM predict
235Phosphoserine(CDC2)HMM predict
235O-linkedHMM predict
235Phosphoserine(CDK)HMM predict
249O-linkedHMM predict
249Phosphoserine(IKK)HMM predict
290Phosphoserine(CDC2)HMM predict
290Phosphoserine(CDK)HMM predict
309Phosphoserine(PKA)HMM predict
332Phosphoserine(ATM)HMM predict
337Phosphoserine(CK1)HMM predict
337Phosphoserine(CK2)HMM predict
365PhosphoserineHMM predict
365Phosphoserine(IKK)HMM predict
384Phosphothreonine(PKC)HMM predict
409N-linkedHMM predict
506N-linkedHMM predict
541Phosphoserine(IKK)HMM predict
604N-linkedHMM predict
611Phosphotyrosine(Jak)HMM predict
685N-linkedHMM predict
702N-linkedHMM predict
705N-linkedHMM predict
711Phosphothreonine(MAPK)HMM predict
726Phosphothreonine(CDC2)HMM predict
726Phosphothreonine(MAPK)HMM predict
761S-palmitoylHMM predict
776N-linkedHMM predict
779N-linkedHMM predict
795Phosphoserine(IKK)HMM predict
796O-linkedHMM predict
800Phosphoserine(ATM)HMM predict
803Phosphothreonine(CDK)HMM predict
803Phosphothreonine(CDC2)HMM predict
809Phosphoserine(PKG)HMM predict
816Phosphoserine(CAMK2)HMM predict
816Phosphoserine(CK2)HMM predict
902Phosphoserine(CDC2)HMM predict
954Phosphoserine(CDK)HMM predict
954Phosphoserine(CDC2)HMM predict
957Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004463
  • Location:chrX 54488613-54539323
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 54540684 54540871 187 1454
Oct1 H2O2-HelaGSE14283 54552306 54552339 33 12999
Oct1 HelaGSE14283 54552306 54552336 30 12998
SRF HepG2GSE8489 54548715 54549432 717 9750
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 54490786 54490919 133 0
CTCF CD4SISSRdata 54490786 54490919 133 0
CTCF G2GSE9613 54490550 54490893 343 0
CTCF G2GSE9613 54491804 54492163 359 0
CTCF G2GSE9613 54496336 54496580 244 0
CTCF G2GSE9613 54508720 54508967 247 0
CTCF G2GSE9613 54515710 54515982 272 0
CTCF G2GSE9613 54519276 54519474 198 0
CTCF G2GSE9613 54520146 54520527 381 0
CTCF G2GSE9613 54524919 54525289 370 0
CTCF G2GSE9613 54538115 54539406 1291 0
ER MCF7GSE19013 54522677 54523293 616 0
Oct1 HelaGSE14283 54519547 54519577 30 0
TFAP2C MCF7GSE21234 54514043 54514435 392 0
hScc1 BcellGSE12603 54538162 54538612 450 0
hScc1 G2GSE9613 54491804 54492096 292 0
hScc1 G2GSE9613 54517531 54518147 616 0
hScc1 G2GSE9613 54522917 54523095 178 0
hScc1 G2GSE9613 54538162 54539406 1244 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
27697 mRNA RP1-112K5.2 chrX 54349878 54354940 31 mRNA FGD1 chrX 54354909 54405620Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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