AutismKB 2.0

Annotation Detail for ALDOA


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Basic Information Top
Gene Symbol:ALDOA ( ALDA,GSD12,MGC10942,MGC17716,MGC17767 )
Gene Full Name: aldolase A, fructose-bisphosphate
Band: 16p11.2
Quick LinksEntrez ID:226; OMIM: 103850; Uniprot ID:ALDOA_HUMAN; ENSEMBL ID: ENSG00000149925; HGNC ID: 414
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
3Phosphotyrosine.
5Phosphotyrosine.
9Phosphothreonine.
13N6-acetyllysine.
36Phosphoserine.
37Phosphothreonine.
39Phosphoserine.
42N6-acetyllysine.
46Phosphoserine.
65Phosphothreonine.
108N6-acetyllysine.
204Phosphotyrosine.
223Phosphotyrosine.
235Phosphothreonine.
241Phosphothreonine.
330N6-acetyllysine.
354Phosphoserine.
356Phosphoserine.
364Phosphotyrosine.
Location(AA) Modifications Resource
13N6-acetyllysine.Swiss-Prot 53.0
36Phosphoserine (By similarity).Swiss-Prot 53.0
39Phosphoserine (By similarity).Swiss-Prot 53.0
42N6-acetyllysine.Swiss-Prot 53.0
45PhosphoserinePhospho.ELM 6.0
46Phosphoserine.Swiss-Prot 53.0
64PhosphothreoninePhospho.ELM 6.0
65Phosphothreonine.Swiss-Prot 53.0
204Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
9Phosphothreonine(MAPK)HMM predict
176Phosphoserine(IKK)HMM predict
235Phosphothreonine(MAPK)HMM predict
276Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000034
  • Location:chr16 29971991-29989234
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 29973897 29974220 323 0
CTCF CD4SISSRdata 29973897 29974220 323 0
CTCF G2GSE9613 29973886 29974291 405 0
H3ac HepG2E 29981992 29982569 577 0
Oct1 HelaGSE14283 29978629 29978658 29 0
P300 T30-glioblastomaGSE21026 29971526 29973073 1547 0
RARA MCF7GSE15244 29979222 29980343 1121 0
Rb QuiescentGSE19898 29972209 29972441 232 0
TFAP2C MCF7GSE21234 29971552 29972896 1344 0
TFAP2C MCF7GSE21234 29979387 29980387 1000 0
VDR GM10855-stimGSE22484 29973340 29974572 1232 0
VDR GM10861-stimGSE22484 29973338 29974574 1236 0
hScc1 BcellGSE12603 29973779 29974105 326 0
hScc1 BcellGSE12603 29982427 29982851 424 0
hScc1 CdLSGSE12603 29973631 29974254 623 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-122 hsa-mir-122 18 19296470
hsa-miR-122* hsa-mir-122 18 19296470
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018